Analysis of Saccular Function With Vestibular Evoked Myogenic Potential Test in Meniere's Disease
AbstractMeniere’s disease is the disorder of inner ear characterized by vertigo, tinnitus and sensorineural hearing loss. The vestibular evoked myogenic potential (VEMP) test could be useful in the analysis of saccular function, and diagnosis of Meniere’s disease. In this study, we’ve analyzed the saccular function, using VEMP test in different groups of Meniere’s disease. Patients were categorized as possible, probable or definite Meniere’s disease groups according to the guideline of American Academy of Otolaryngology-Head and Neck Surgery. The exclusion criteria were neuromuscular system diseases, diseases of central nervous system, inner ear disorders, conductive hearing loss, a history of ototoxic drug consumption, being a drug abuser and a positive history of inner ear surgery or manipulations. The VEMP test is the recording of positive and negative waves from sternocleidomastoid muscle that is made by an auditory click to the ear. From the total of 100 patients, the waves of VEMP test was seen in 59 patients which 19 patients had abnormal amplitude, and latency and 40 patients were with normally recorded waves. There was a significant relationship between the severity of hearing loss and a VEMP test without any recorded waves. Most of the cases with ‘no wave recorded’ VEMP test, were patients with severe hearing loss. However, there wasn’t any relation between the pattern of hearing loss and ‘no wave recorded’ VEMP test. VEMP test could be a valuable diagnostic clue especially in patients with definite Meniere’s disease.
Crane BT, Schessel DA, Nedzelski J, Minor LB.Peripheral vestibular disorders. In: Flint PW, Haughey BH, Lund WJ, Niparko JK, Richardson MA, Robbins KT, et al, eds. Cummings otolaryngology Head and Neck surgery. 5th ed. Philadelphia, USA: Elsevier, 2010:2328-46.
Alexander TH, Harris JP. Current epidemiology of Meniere’s syndrome. Otolaryngol Clin N Am 2010;43:965-70.
House JW, Doherty JK, Fisher LM, Derebery MJ, Berliner KI. Meniere's disease: prevalence of contralateral ear involvement. Otol Neurotol 2006;27:355-61.
Hebbar GK, Rask-Andersen H, Linthicum Jr FH. Three- dimensional analysis of 61 human endolymphatic ducts and sacs in ears with and without Meniere's disease. Ann Otol Rhinol Laryngol 1991;100:219-25.
Albers FW, Van Weissenbruch R, Casselman JW. 3DFT- magnetic resonance imaging of the inner ear in Meniere's disease. Acta Otolaryngol 1994;114:595-600.
Jaccobson GP, Mccaslin DC. The vestibular evoked myogenic potentials and other sonomotor evoked potentials. In: Burkard RS, Don M, Eggermont JJ, eds. Auditory evoked potentials: basic principles and clinical applications. 1st ed. Philadelphia: Lippincott Williams & Wilkins, 2007:572-99.
Katayama N, Yamamota M, Teranishi M, Naganawa S, Nakata S, Sone M, et al. Relationship between endolymphatic hydrops and vestibular evoked myogenic potential. Acta otolaryngol 2010;130:917-23.
Kim-lee Y, Ahn JH, Kim YK, Yoon TH. Tone burst vestibular evoked myogenic potentials: diagnostic criteria in patients with Meniere’s disease. Acta otolaryngol 2009;129:924-8.
Zhou G, Cox LC. Vestibular evoked myogenic potential:history and over view. Am J Audiol 2004;13:135-43.
Yoon TH, Paparella MM, Schachern PA, Le CT. Cellular changes in Reissner's membrane in endolymphatic hydrops. Ann Otol Rhinol Laryngol 1991;100:288-93.
Schuknecht HF, Suzuka Y, Zimmermann C. Delayed endolymphatic hydrops and its relationship to Meniere's disease. Ann Otol Rhinol Laryngol 1990;99:843-53.
Bergström T, Edström S, Tjellström A, Vahlne A.Meniere's disease and antibody reactivity to herpes simplex virus type I polypeptides. Am J Otolaryngol 1992;13:295-300.
Xenellis JE, Linthicum FH Jr, Galey FR. Lermoyez's syndrome: histopathologic report of a case. Ann Otol Rhinol Laryngol 1990;99:307-9.
Friberg U, Stahle J, Svedberg A. The natural course of Meniere's disease. Acta Otolaryngol Suppl 1984;406:72-7.
Black FO, Kitch R. A review of vestibular test results in Meniere's disease. Otolaryngol Clin North Am1980;13:631-42.
Merchant SN, Rauch SD, Nadol JB Jr. Meniere's disease.Eur Arch Otorhinolaryngol 1995;252:63-75.
Campbell KC, Harker LA, Abbas PJ. Interpretation of electrocochleography in Meniere's disease and normal subjects. Ann Otol Rhinol Laryngol 1992;101:496-500.
Zhou G, Cox LC. Vestibular evoked myogenic potentials:history and overview. Am J Audiol 2004;13:135-43.
Kushiro K, Zakir M, Ogawa Y, Sato H, Uchino Y. Saccular and utricular inputs to sternocleidomastoid motoneurons of decerebrate cats. Exp Brain Res 1999;126:410-6.
Felipe L, Santos MA, Gonçalves DU. Vestibular evoked myogenic potential: evaluation of responses in normal subjects. Pro Fono 2008;20:249-54.
Taylor RL, Wijewaardene AA, Gibson WP, Black DA, Halmagyi GM, Welgampola MS. The vestibular evoked potential profile of Meniere’s disease. Clin neurophysiol 2011;122:1256-63.
Zarei M, Adel Ghahraman M, Daneshi A, Emamjomeh H, Memari F, Akbari M, et al. Comparison of the prevalence and latency of vestibular evoked myogenic potential in normal and symptomatic and asymptomatic Meniere’s disease patients. Audiol 2009;18:36-44.
Jankly KL. Vestibular evoked myogenic potential (VEMP) testing: normative threshold response curves and effects of age. Acad Audiol 2009;20:514-22.
de Waele C, Huy PT, Diard JP, Freyss G, Vidal PP.Saccular dysfunction in Meniere’s disease. AM J Otol 1999;20;223-32.