Acta Medica Iranica 2016. 54(2):140-145.

Benefits of Pharmacist’s Participation on Hospitalist Team
Simin Mahdikhani, Fatemeh Dabaghzadeh


This study was performed to assess the incidence of medication errors and irrational use of human albumin in two wards of our hospital and also aimed to evaluate the ability of pharmaceutical care center and pharmacists in improving patient care. Albumin administration was evaluated for patients who received albumin during the study period, in gastroenterology and general surgery wards. The indications for Albumin administration were evaluated on the basis of reliable guidelines. The prescribing errors were simultaneously evaluated by reviewing patients’ medical records. Prescribing errors were defined as selecting improper drug (based on indications, contraindications, known allergies, drug-class duplications and drug-drug interactions), dose, dosage form, and route of administration. It was found that 465 containers of human albumin solution 20 % were used for 54 patients treated in gastroenterology and general surgery wards of our hospital. A total of 306 (65.81%) vials of the albumin administrations were in concordance with the reliable protocol. The cost of irrational use of this drug (159 vials) for patients is equivalent to $ 8215. From 609 reviewed cases, 81 prescribing errors were detected in 64 patients. This study showed that the pharmacists were effective in identifying irrational drug use and medication errors.


Pharmacist; Drug utilization review; Albumin; Medication errors

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Kaboli PJ, Hoth AB, McClimon BJ, et al. Clinical pharmacists and inpatient medical care: a systematicreview. Arch Intern Med 2006;166(9):955-64.

Francis J, Abraham S. Clinical pharmacists: Bridging the gap between patients and physicians. Saudi Pharm J 2014;22(6):600-2.

Lifshitz AE, Goldstein LH, Sharist M, et al. Medication prescribing errors in the prehospital setting and in the ED. Am J Emerg Med 2012;30(5):726-31.

Montesi G, Lechi A. Prevention of medication errors: detection and audit. Br J Clin Pharmacol. 2009;67(6):651-5.

Franklin BD, Reynolds M, Shebl NA, et al. Prescribing errors in hospital inpatients: a three-centre study of their prevalence, types and causes. Postgrad Med J 2011;87(1033):739-45.

Bosma L, Jansman FG, Franken AM, et al. Evaluation of pharmacist clinical interventions in a Dutch hospital setting. Pharm World Sci 2008;30(1):31-8.

Barber N, Rawlins M, Franklin BD. Reducing prescribing error: competence, control, and culture. Qual Saf Health Care 2003;12(Suppl 1):i29-32.

Khalili H, Farsaei S, Rezaee H, et al. Role of clinical pharmacists’ interventions in detection and prevention of medication errors in a medical ward. Int J Clin Pharm 2011;33(2):281-4.

Wang HY, Chan AL, Chen MT, et al. Effects of pharmaceutical care intervention by clinical pharmacists in renal transplant clinics. Transplant Proc 2008;40(7):2319-23.

Cunningham KJ. Analysis of clinical interventions and the impact of pediatric pharmacists on medication error prevention in a teaching hospital. J Pediatr Pharmacol Ther 2012;17(4):365-73.

Aljbouri TM, Alkhawaldeh MS, Hasan TA, et al. Impact of clinical pharmacist on cost of drug therapy in the ICU.Saudi Pharm J 2013;21(4):371-4.

Khalili H, Karimzadeh I, Mirzabeigi P, et al. Evaluation of clinical pharmacist's interventions in an infectious diseases ward and impact on patient's direct medication cost. Eur J Intern Med 2013;24(3):227-33.

Patel R, Butler K, Garrett D, et al. The Impact of a Pharmacist’s Participation on Hospitalists’ Rounds. Hospital Pharmacy 2010;45(2):129-34.

Talasaz AH, Jahangard-Rafsanjani Z, Ziaie S,et al. Evaluation of the pattern of human albumin utilization at a university affiliated hospital. Arch Iran Med 2012;15(2):85-7.

Somers A, Bauters T, Robays H, et al. Evaluation of human albumin use in a university hospital in Belgium. Pharm World Sci 2002;24(3):111-6.

Nejad MM, Hayatshahi A, Javadi M, et al. Evaluation of Human Albumin Use in Bone Marrow Transplantation Patients in a University Hospital in Iran: A Retrospective Study. Int J Hematol Oncol Stem Cell Res 2010;4(3):14-20.

King W-S, Roland K, Selin S, et al. Introduction of guidelines for the use of albumin and the effect on albumin prescribing practices in British Columbia. Bull Vancouver Med Assoc 2012;54(1):34-8.

Jahangard-Rafsanjani Z, Javadi MR, Torkamandi H, et al.The Evaluation of Albumin Utilization in a Teaching University Hospital in Iran. Iran J Pharm Res2011;10(2):385-90.

Kazemi Y, Hadavand N, Hayatshahi A, et al. Albumin Utilization in a Teaching Hospital in Tehran: Time to Revisethe Prescribing Strategies. J Pharm Care 2014;1(4):127-32.

Boldt J. Use of albumin: an update. Br J Anaesth2010;104(3):276-84.

Pharmacists ASoH-S. ASHP guidelines on preventingmedication errors in hospitals. Am J Hosp Pharm 1993;50(2):305-14.

Sadeghi K, Mohammadi M, Najmeddin F, et al. Pharmacist-Led Medication Review: Supports for New Role ofPharmacists. J Pharm Care 2014;1(4):153-60.

Zhou T, Lu S, Liu X, et al. Review of the rational use and adverse reactions to human serum albumin in the People’s Republic of China. Patient Prefer Adherence 2013;7:1207-12.

Üyetürk Ü, Özbey G, Üyetürk U, et al. Evaluation of the Use of Human Albumin Solution in Gaziosmanpasa University Faculty of Medicine Hospital. Yeni Tıp Dergisi 2010;27:165-8.

Angalakuditi M, Gomes J. Retrospective drug utilization review: impact of pharmacist interventions on physician prescribing. Clinicoecon Outcomes Res. 2011;3:105-8.

Mansouri A, Ahmadvand A, Hadjibabaie M, et al. Types and severity of medication errors in Iran; a review of the current literature. Daru 2013;21(1):49-59.

Zargarzadeh AH. Medication Safety in Iran. J Pharm Care 2014;1(4):125-6.

Seeley CE, Nicewander D, Page R, Dysert PA. A baseline study of medication error rates at Baylor University Medical Center in preparation for implementation of a computerized physician order entry system. Proc (Bayl Univ Med Cent) 2004;17(3):357-61.

Zeraatchi A, Talebian M, Nejati A, et al. Frequency and types of the medication errors in an academic emergency department in Iran: The emergent need for clinical pharmacy services in emergency departments. J Res Pharm Pract 2013;2(3):118-22.

Dabaghzadeh F, Rashidian A, Torkamandi H, et al. Medication errors in an emergency department in a large teaching hospital in Tehran. Iran J Pharm Res 2013;12(4):937-42.

Pham JC, Story JL, Hicks RW, et al. National study on the frequency, types, causes, and consequences of voluntarily reported emergency department medication errors. J S. Mahdikhani, et al. Acta Medica Iranica, Vol. 54, No. 2 (2016) 145 Emerg Med 2011;40(5):485-92.

Al-Dhawailie A. Inpatient prescribing errors and pharmacist intervention at a teaching hospital in Saudi Arabia. Saudi Pharm J 2011;19(3):193-6.


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