A Woman with Normotensive Primary Hyperaldosteronism
AbstractNormotensive hyperaldosteronism is a rare disorder. It is usually diagnosed with hypokalemia or an adrenal mass. Our patient was a 27-year-old female presented with weakness. She had normal blood pressure, hypokalemia, high plasma aldosterone level and suppressed plasma renin activity. After the saline load, test aldosterone didn’t show suppression. Adrenal computed tomography revealed a left adrenal mass. The patient was treated with spironolactone and potassium supplement. Surgical adrenalectomy was done. Final pathologic diagnosis was benign adrenocortical adenoma without capsular invasion. In postoperative course serum, potassium was normal.
Kanoun F, Mabrouki T, Mekaouer A, et al. Normotensive Primary Aldosteronism: A Case Report. Int J Endocrinol 2009;5(1).
Satoh F, Morimoto R, Iwakura Y, et al. Primary aldosteronism. Rev Endocr Metab Disord 2011;12(1):11-4.
Calhoun DA. Aldosteronism and hypertension. Clin J Amn Soc Nephrol 2006;1(5):1039-45.
Williams JS, Williams GH, Raji A, et al. Prevalence of primary hyperaldosteronism in mild to moderate hypertension without hypokalaemia. J Hum Hypertens 2006;20(2):129-36.
Medeau V, Moreau F, Trinquart L, et al. Clinical and biochemical characteristics of normotensive patients with primary aldosteronism: a comparison with hypertensive cases. Clin Endocrinol (Oxf) 2008;69(1):20-8.
Paolo Rossi G. Does primary aldosteronism exist in normotensive and mildly hypertensive patients, and should we look for it? Hypertens Res 2011;34(1):43-6.
Mulatero P, Stowasser M, Loh KC, et al. Increased diagnosis of primary aldosteronism, including surgically correctable forms, in centers from five continents. J Clin Endocrinol Metab 2004;89(3):1045-50.