Eighty Kilograms Weight Reduction in a Case of Obstructive Sleep Apnea with Several Comorbidities: Did the Conditions Improve?
Obstructive sleep apnea (OSA) together with metabolic disorders is common in severely obese patients. Weight reduction is considered as a treatment modality in these cases while few of them can succeed in considerable weight loss. Here, we present a severely obese man with body mass index of 54 suffered from OSA, type 2 diabetes, hypothyroidism, and hypertension. He intentionally lost 80 kilograms weight during the 2-year follow-up. Diabetes and hypertension completely resolved with considerable improvement in OSA syndrome after this huge weight reduction.
Young T, Hutton R, Finn L, et al. The gender bias in sleep apnea diagnosis: are women missed because they have different symptoms? Arch Intern Med 1996;156(21):2445-51.
Kyzer S, Charuzi I. Obstructive sleep apnea in the obese. World J Surg 1998;22(9):998-1001.
Chung F, Yegneswaran B, Liao P, et al. STOP questionnaire: a tool to screen patients for obstructive sleep apnea. Anesthesiology 2008;108(5):812-21.
Tuomilehto HP, Seppa JM, Partinen MM, et al. Lifestyle intervention with weight reduction: first-line treatment in mild obstructive sleep apnea. Am J Respir Crit Care Med 2009;179(4):320-7.
Foster GD, Sanders MH, Millman R, et al. Obstructive sleep apnea among obese patients with type 2 diabetes. Diabet Care 2009;32(6):1017-9.
Buchwald H, Estok R, Fahrbach K, et al. Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis. Am J Med 2009;122(3):248-56.
Sugerman HJ, Wolfe LG, Sica DA, et al. Diabetes and hypertension in severe obesity and effects of gastric bypass-induced weight loss. Ann Surg 2003;237(6):751-6.
Jha A, Sharma SK, Tandon N, et al. Thyroxine replacement therapy reverses sleep-disordered breathing in patients with primary hypothyroidism. Sleep Med 2006;7(1):55-61.
Resta O, Pannacciulli N, Di Gioia G, et al. High prevalence of previously unknown subclinical hypothyroidism in obese patients referred to a sleep clinic for sleep disordered breathing. Nutr Metab Cardiovasc Dis 2004;14(5):248-53.
Raftopoulos Y, Gagné DJ, Papasavas P, et al. Improvement of hypothyroidism after laparoscopic Rouxen- Y gastric bypass for morbid obesity. Obes Surg 2004;14(4):509-13.
Dahlqvist J, Dahlqvist Å, Dahlqvist J, et al. Physical findings in the upper airways related to obstructive sleep apnea in men and women. Acta Otolaryngol 2007;127(6):623-30.