DEUX CAS D'ERYTHROMYELQSE ET UN CAS D'ERYTHROLEUCOSE EN IRAN

Abstract

Two cases of Erythremic Myelosis and one case of Erythroleukemia in Iran Erythremic Myelosis or Di-Guglielmo disease is characterized by generalized and systemic proliferation. selectively affecting erythropoietic apparatus and according to the course; there ure acute and chronic forms. Thus the condition has much in common with leukemia but depends on a proliferation of erythrocytic series instead of the leucocytes. Erythroleukemia is a name which has been given to a somewhat similar condition in which there is combined hyperplasia of the erythropoietic and leukopoietic tissues. We have seen two cases of Erythremic Myelosis for the f irst time in Iran. The first was a woman of 25 years old and the other one a man of 65 years old. Both patients had severe anemia> enlargement of the liver aud spleen together with hemorrhagic manifestations. Blood changes showed the presence of numerous er ythroblasts, and in bone marrow a severe proliferation of the erythroblast series could he seen. Both patients died from a severe renal hemorrhage. A case of erythroleukemia was found in a boy, of 1,5 yea.· with severe anemia, liver and spleen enlargements and fever. examination showed the presence of immature white cells [Ieucob.lasts] and numerous nucleated red cells. In the bone marrow the proliferation of the erythropoietic series wus evident.