Unveiling Parry-Romberg Syndrome With Native Demyelinating Etiology as the Underlying Cause
Abstract
Parry-Romberg Syndrome (PRS) is an atypical condition characterized by hemiatrophy of the face. Despite its rarity, the precise pathophysiological processes underlying its etiology remain elusive. While previous reports have hinted at the potential involvement of autoimmune factors, our case report aims to explore a novel perspective. Specifically, we pose the question of whether multiple sclerosis (MS) could be a plausible causative factor for PRS. Additionally, we investigate the potential association between Radiologically Isolated Syndrome (RIS) and the development of Parry-Romberg Syndrome.
2. Fry JA, Alvarellos A, Fink CW, Blaw ME, Roach ES. Intracranial findings in progressive facial hemiatrophy. J Rheumatol 1992;19:956-58.
3. Moko SB, Mistry Y, Blandin de Chalain TM. Parry-Romberg syndrome: intra-cranial MRI appearances. J Craniomaxillofac Surg 2003;31:321-24.
4. El-Kehdy J, Abbas O, Rubeiz N. A review of Parry-Romberg syndrome. J Am Acad Dermatol 2012;67:769-84.
5. Okumura A, Ikuta T, Tsuji T, Kato T, Fukatsu H, Naganawa S, et al. Parry-Romberg syndrome with a clinically silent white matter lesion. AJNR Am J Neuroradiol 2006;27:1729-31
6. Tkachenko E, Cunningham MJ, O’Donnell PJ, Levin NA. Adult-onset bilateral Parry-Romberg syndrome. JAAD Case Rep 2019;5:209-12.
Files | ||
Issue | Vol 61 No 12 (2023) | |
Section | Case Report(s) | |
DOI | https://doi.org/10.18502/acta.v61i12.16374 | |
Keywords | ||
Parry-romberg syndrome Hemifacial atrophy Multiple sclerosis Radiologically isolated syndrome |
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