Original Article

Comparing the Efficacy of “Spray as You Go” Technique Versus Combined Airway Nerve Block and “Spray as You Go” as Topical Anesthesia During Flexible Bronchoscopy; a Double-Blinded Randomized Clinical Trial

Abstract

Flexible bronchoscopy is employed to diagnose a range of respiratory disorders. Local airway anesthesia is mandatory to facilitate tracheal intubation. It is commonly done by injection of diluted lidocaine through working channel of bronchoscope via Spray-as-you-go (SAYGO) method. Other methods such as airway nerve block (ANB) by direct injection of lidocaine are also used to increase patient comfort. The aim of this study was to compare patient and physician satisfaction during bronchoscopy in two groups receiving SAGO alone versus combination of SAYGO and ANB. In a double-blinded randomized clinical trial, 68 patients undergoing bronchoscopy were divided into two groups. The first group received local anesthesia solely through the SAYGO method, while the second group received a combination of SAYGO and ANB. Both groups received intravenous sedation. The anesthesia level was assessed using Ramsay score. Patient and physician satisfaction with bronchoscopy was evaluated on a numeric scale of 1 to 5. Combination of ANB and SAYGO resulted in significantly higher satisfaction score both in physician [3.4±1.6 and 4.6±0.8] and patients [3.5±1.3 and 4.9±0.4] (P<0.001). Thirteen individuals (38.2%) in the SAYGO and four individuals (11.8%) in SAYGO+ANB experienced a drop in oxygen levels (P=0.023). Additionally, sedation levels (Ramsay sedation scale score) were significantly higher in the first group (4) compared to the second group (3) (P=0.001). Combining ANB with SAYGO resulted in higher patient and physician comfort during bronchoscopy in comparison to SAYGO alone with no increase in complications.

1. Madan K, Mohan A, Agarwal R, Hadda V, Khilnani GC, Guleria R. A survey of flexible bronchoscopy practices in India: The Indian bronchoscopy survey (2017). Lung India 2018;35:98-107.
2. Lee HJ, Haas AR, Sterman DH, Solly R, Vachani A, Gillespie CT. Pilot randomized study comparing two techniques of airway anaesthesia during curvilinear probe endobronchial ultrasound bronchoscopy (CP‐EBUS). Respirology 2011;16:102-6.
3. Simmons ST, Schleich AR. Airway regional anesthesia for awake fiberoptic intubation. Reg Anesth Pain Med 2002;27:180-92.
4. Isaac P, Barry J, Vaughan R, Rosen M. A jet nebuliser for delivery of topical anaesthesia to the respiratory tract A comparison with cricothyroid puncture and direct spraying for fibreoptic bronchoscopy. Anaesthesia 1990;45:46-8.
5. Dhasmana S, Singh V, Pal US. Nebulisation versus spray-as-you-go airway topical anaesthesia in patients with temporomandibular joint ankylosis using 2% lignocaine. J Maxillofac Oral Surg 2015;14:398-402.
6. Madan K, Mittal S, Mohan A. Lignocaine delivery for topical anesthesia during bronchoscopy: recent advances. Lung India 2020;37:449-50.
7. Webb A, Fernando S, Dalton H, Arrowsmith J, Woodhead M, Cummin A. Local anaesthesia for fibreoptic bronchoscopy: transcricoid injection or the" spray as you go" technique? Thorax 1990;45:474-7.
8. Wahidi MM, Jain P, Jantz M, Lee P, Mackensen GB, Barbour SY, et al. American College of Chest Physicians consensus statement on the use of topical anesthesia, analgesia, and sedation during flexible bronchoscopy in adult patients. Chest 2011;140:1342-50.
9. Hamad S, Al-Alawi M, Devaney N, Subramaniam A, Lane S. Evaluation of the efficacy of transcricoid lignocaine as adjunctive local anaesthesia for fiberoptic bronchoscopy. Ir J Med Sci 2015;184:273-6.
10. Madan K, Mittal S, Gupta N, Biswal SK, Tiwari P, Hadda V, et al. The Cricothyroid versus Spray-As-You-Go Method for Topical Anesthesia during Flexible Bronchoscopy: The CRISP Randomized Clinical Trial. Respiration 2019;98:440-6.
11. Chandra A, Banavaliker JN, Agarwal MK. Fiberoptic bronchoscopy without sedation: Is transcricoid injection better than the “spray as you go” technique? Indian J Anaesth 2011;55:483-7.
12. Madan K, Iyer H, Arunachalam M, Mittal S, Tiwari P, Hadda V, et al. The cricothyroid versus the spray-as-you-go method for topical anesthesia during flexible bronchoscopy: A systematic review and meta-analysis of randomized controlled trials. Lung India 2021;38:416-24.
13. Mittal S, Gupta N, Iyer H, Biswal SK, Tiwari P, Hadda V, et al. The cricothyroid versus Spray-As-You-Go method for topical anesthesia during Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA): The CRISPEN randomized clinical trial. Lung India 2021;38:223-8.
14. Mathur PR, Jain N, Kumar A, Thada B, Mathur V, Garg D. Comparison between lignocaine nebulization and airway nerve block for awake fiberoptic bronchoscopy-guided nasotracheal intubation: a single-blind randomized prospective study. Korean J Anesthesiol 2018;71:120-6.
15. Khandelwal M, Saini VK, Kothari S, Sharma G. Role of lignocaine nebulization as an adjunct to airway blocks for awake fiber-optic intubation: a comparative study. Anesth Essays Res 2018;12:735-41.
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IssueVol 61 No 12 (2023) QRcode
SectionOriginal Article(s)
DOI https://doi.org/10.18502/acta.v61i12.16370
Keywords
Bronchoscopy Local anesthesia Lidocaine Airway nerve block

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How to Cite
1.
Rafiei E, Paknejad O, Eftekhar N, Salehi O, Rashidi P, Gholamzadeh M, Asadi Gharabaghi M. Comparing the Efficacy of “Spray as You Go” Technique Versus Combined Airway Nerve Block and “Spray as You Go” as Topical Anesthesia During Flexible Bronchoscopy; a Double-Blinded Randomized Clinical Trial. Acta Med Iran. 2024;61(12):736-742.