Association of Serum Sodium, Potassium and High-Sensitivity C-Reactive Protein Levels With Mitral Regurgitation and Risk Factors in Patients With Acute Coronary Syndrome

Abstract

Acute coronary syndrome (ACS) is a condition that manifests itself when there is a reduction in the amount of blood that flows to the coronary arteries. This can lead to damage to the heart muscle or possibly death of the heart muscle. The study was conducted with the intention of determining whether there were any alterations in the levels of sodium, potassium, and high-sensitivity C-reactive protein that were found in the serum of individuals who were diagnosed with acute coronary syndrome (ACS). In addition, the objective of this study was to evaluate the relationship between these levels and risk factors such as quitting smoking, having dyslipidemia, being overweight, and having mitral regurgitation. The study had a total of 133 participants, with 83 patients being assigned to the study group and 50 individuals being assigned to the control group. A specific group of people who had recently been diagnosed with ACS made comprised the members of the study group. Both groups' blood samples were taken and then flame photometry using the Bio-Lab Diagnostic kit was used to determine the levels of serum electrolytes (Na+ and K+). Furthermore, calorimetry was utilized in order to estimate the levels of the lipid profile. The levels of sodium, C-reactive protein, and potassium in the serum were shown to have significantly increased across all age groups when compared to the control group. Despite the fact that the female group had slightly higher mean±standard deviation values of serum sodium, potassium, and C-reactive protein concentrations compared to the male group, this difference did not meet the criteria for statistical significance. When comparing the mean±standard deviation levels of serum sodium, potassium, and C-reactive protein in the presence or absence of dyslipidemia, smoking, or obesity, the results of the T-tests revealed that there were no significant differences. There was a correlation between the severity of mitral regurgitation and the mean±standard deviation values of serum sodium, potassium, and C-reactive protein concentrations. The early evaluation of serum electrolyte levels is not only necessary for appropriate replenishment but also has the potential to assist in the diagnosis of acute coronary syndrome. C-reactive protein has been shown to be associated with the development of acute coronary syndrome. and we have also demonstrated that it has the potential to serve as a biomarker for both the risk and severity of ACS. It is possible to determine the severity of mitral regurgitation by observing the elevated levels of C-reactive protein, sodium and potassium in the serum.