Silent Thrombosis, Loud Pain: Portal Vein Thrombosis Presenting With Flank Pain
Abstract
This case report describes a 67-year-old male who presented with right flank pain and unintentional weight loss, subsequently diagnosed with spontaneous portal vein thrombosis (PVT). Despite the absence of cirrhosis, malignancy, or identifiable prothrombotic conditions, imaging and anticoagulation therapy played a critical role in managing his condition. This report underscores the importance of early diagnosis, individualized anticoagulation therapy, and thorough investigation of underlying causes in the management of PVT.
1. Condat B, Pessione F, Hillaire S, et al. Current outcome of portal vein thrombosis in adults: Risk and benefit of anticoagulant therapy. *Gastroenterology*. 2001;120(2):490–7.
2. DeLeve LD, Valla DC, Garcia-Tsao G. Vascular disorders of the liver. *Hepatology*. 2009;49(5):1729–64.
3. Zhang W, Gao F, Li Y, et al. Non-cirrhotic portal vein thrombosis: A concise review. *World J Gastroenterol*. 2020;26(47):7384–98.
4. Tarantino G, Capone D, Polimeno L. Risk of thrombosis in patients with chronic liver disease. *World J Gastroenterol*. 2013;19(40):6662–76.
5. Tripodi A, Mannucci PM. The coagulopathy of chronic liver disease. *N Engl J Med*. 2011;365(2):147–56.
6. Handa P, Bruzzi S, Wang Q, et al. Anticoagulation in chronic liver disease patients with portal vein thrombosis: A systematic review and meta-analysis. *Thromb Res*. 2021;202:52–60.
2. DeLeve LD, Valla DC, Garcia-Tsao G. Vascular disorders of the liver. *Hepatology*. 2009;49(5):1729–64.
3. Zhang W, Gao F, Li Y, et al. Non-cirrhotic portal vein thrombosis: A concise review. *World J Gastroenterol*. 2020;26(47):7384–98.
4. Tarantino G, Capone D, Polimeno L. Risk of thrombosis in patients with chronic liver disease. *World J Gastroenterol*. 2013;19(40):6662–76.
5. Tripodi A, Mannucci PM. The coagulopathy of chronic liver disease. *N Engl J Med*. 2011;365(2):147–56.
6. Handa P, Bruzzi S, Wang Q, et al. Anticoagulation in chronic liver disease patients with portal vein thrombosis: A systematic review and meta-analysis. *Thromb Res*. 2021;202:52–60.
| Files | ||
| Issue | Articles in Press: Vol 64 No 02 (2026) | |
| Section | Case Report(s) | |
| Keywords | ||
| Portal vein thrombosis (PVT) Abdominal pain anticoagulation | ||
| Rights and permissions | |
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Aarabi S. Silent Thrombosis, Loud Pain: Portal Vein Thrombosis Presenting With Flank Pain. Acta Med Iran. 2026;64(02).
