THE RELATIONSHIP OF THE SERUM URIC ACID TO SERUM LIPIDS: A STUDY OF YOUNG NORMAL SUBJECTS IN EHERAN

Abstract

Serum uric acid , trigly c eride and c holestero l l e vel s were measured in 851 healthy adults in Tehe ran , I r a n . Careful l aboratory and clinical e v a l ua t ion wa s undertaken to exclude any medical problems. Onl y 65% were on iddeal weigh t .The mean uric a c i d v a l ues were 6.1 f or male s and 5 . 1 f or f emale s under 30 years of age. Uric acid l ev e ls above 6mg in females and 7rng in males were obs e rved i n 17% and 27% of subj ects, respectively. Uri c acid values were higher in the studied population compared t o the Nort h American and Europ ean studie s-Increased body weight had t he best cor rel a tion with e leva t ed uric acid l evels. There was s tati s t i cal ly s ignif i c a nt small positive cor rel a t i o n between uric acid and triglyceride, chol esterol and triglyceride, but there was no such correlation between uric acid and c ho l est e rol . Exclusion o f o v - erweight subj ects d i d not abolish t he association of high uric acid wi th h jo~pr ~ r191yceri de l evels. This study a lso provided s ome c r ter i a f or normal va l ue s o f s erum uric acid ,cholesterol, and triglyceride of healthy subjects in our c ountry.