VERRUCOUS CARCINOMA OF THE LARYNXThe Clinical and Pathological Reports of 11 Cases

Abstract

Verrucous carcinoma is a unique clinical and pathological entity which has been recognised in the recent years. It is a variant of well-differentiated squamous cell carcinoma which may occur in the larynx; other anatomic locations such as: the oral cavity, anogenital region, and skin may be involved. It accounts for 1-2% of all laryngeal cancers. The clinical, histopathological and biologic features of this neoplasm differ from that of conventional squamous cell carcinoma. Therefore, close communication between pathologist and laryngologist is necessary for a correct diagnosis.
Eleven cases of verrucous carcinoma which were collected in our institu¬tion within the past ten years are going to be reported. The clinical and pathological features will be discussed. It seems surgical excision is the treatment of choice and irradiation must be discouraged since anaplastic transformation and recurrences after irradiation has been reported.