"A prospective study of etiologies of Hirsutism and screening for non classic congenital adrenal hyperplasia due to 21 Hydroxylase deficiency in 93 female adolescents "

Abstract

In this study 93 hirsute females (Ferryman and Gallway score > 8) referred to institute of endocrinology & metabolism and office were assessed. Baseline testosterone (Tes), Dehydroepiandrosterane sulfate (DHEA-SO4). Follicular stimulating hormone (FSH). Leuteinizing hormone (LH), Prolactin (PRL), thyroid stimulating hormone (TSH), baseline 17 hydroxyprogesterone (17 OHP) and in some cases ACTH stimulation test for screening of non classic congenital adrenal hyperplasia (NC-CAH) due to 21 hydroxylase deficiency was done. The ovaries were visualized by ultrasonography in 56 patients, of the 93 hirsute female, 5 had NC-CAH (5.4%), 46 patients diagnosed as having polycystic ovary syndrome (49.5%) and 42 cases diagnosed as having idiopathic hirsutism (45.1%).