FACTORS AFFECTING THE OUTCOME OF OOCYTE DONATION CYCLES

Abstract

The success of oocyte donation is influenced by multiple factors. We performed a retrospective analysis to evaluate prognostic factors in oocyte donation cycles. The main outcome measurements including recipient age, donor age, estradiol level in midcycle, the day of transfer and number of transferred embryos were not different in pregnant and non pregnant groups. Endometrial pattern but not endometrial thickness was useful in predicting pregnancy outcome. Clinical pregnancy rates were not different relative to etiology of infertility. Clinical pregnancy rates in poor responders and patients with ovarian failure were 23.8% and 26.7%, respectively. Clinical pregnancy rate for zygote intrafallopian transfer (ZIFT) and rapid ZIFT was 31% vs 11.1% for uterine embryo transfer.Predictive factors for pregnancy in oocyte donation cycle were endometrial pattern and route of transfer (ZIFT and rapid ZIFT).