EVALUATION OF A BREAKFAST AS SCREENING TEST FOR THE DETECTION OF GESTATIONAL DIABETES

Abstract

A standard breakfast was evaluated as a screening test (BT) for gestational diabetes in a case-control study. Blood sugar (BS) was measured 1 hour after a breakfast that had 50gr simple sugar and was designed based on women preferences. In the same women glucose challenge test (GCT, 50gr 1hour glucose screening test) was performed one week later in randomized sequential. Cutoff values for both tests was 130 mg/dl. For both or one positive test GTT (100gr-oral glucose tolerance test) was performed. Sensitivity and specificity; optimal cutoff and concordance of both tests with GTT were calculated by X2, receiver operating characteristic (ROC) curve and kappa test. 41 women (29.3%) had positive GCT and 28 women (20%) had positive BT. 12 women (8.57%) had positive GTT. For BT and GCT, a sensitivity of 83.3% and 91.7% and specificity of 85.9% and 76.6% with cutoff level ≥ 130 mg/dl at 60 minute were found respectively. Optimal cutoff for BT and GCT were 130 mg/dl and 135 mg/dl respectively. Concordance of GTT with GCT and BT was 0.429 and 0.432, respectively. Standard breakfast can be used as an alternative method for assessing carbohydrate intolerance in pregnancy with same physiological response, better compliance and low cost.