Validity of Serum Sodium and Calcium Screening in Children
Abstract
Febrile convulsion (FC) is the most common seizure disorder in young children. Different predisposing factors have been suggested to enhance the susceptibility to febrile seizure and its recurrence. The main objective of this study was to identify the adverse effect of electrolytes disturbance in FC and its recur-rence. The medical records of 175 children with convulsive disorders were reviewed. Patients were divided into 3 groups. Group A (n=71) with simple febrile convulsion (FC) and group B (n=54) with recurrent FCs. Fifty children (group C) with non-FC served as control. Serum sodium and calcium concentrations were significantly lower in groups A and B compared to the control group. Serum sodium level was not significantly different between group A and B patients (134.4 vs. 134.7 mEq/l) but was significantly lower in group A than the control group (P= 0.014). Serum calcium concentration did not differ among the 3 groups. Minor abnormal levels of serum sodium concentration were detected in children with febrile convulsions. Thus, routine serum electrolytes screening are not recommended in febrile seizure.
Al-Ossaimi S, Jawad NH. Recent advances in febrile seizures. J Kuwait Med 2001; 33(1): 7-12.
Kiviranta T, Airaksinen EM. Low sodium levels in serum are associated with subsequent febrile seizures. Acta Paediatr 1995; 84(12): 1372-4.
Chiarelli F, De Palma C, Verrotti A, Lombardi G, Domizio
S. Electrolytic changes in febrile convulsions. Pediatr Med Chir 1985; 7(2): 249-52.
Kiviranta T, Tuomisto L, Airaksinen EM. Osmolality and electrolytes in cerebrospinal fluid and serum of febrile children with and without seizures. Eur J Pediatr 1996; 155(2): 120-5.
Kenney RD, Taylor JA. Absence of serum chemistry abnormalities in pediatric patients presenting with seizures. Pediatr Emerg Care 1992; 8(2): 65-6.
van Stuijvenberg M, van Gijssel EN, Steyerberg EW, Moons KG, Derksen-Lubsen G, Moll HA. Seizures associated with fever: clinical data as predictors for normal biochemical blood levels. Eur J Pediatr 1998; 157(7): 592-8.
Hugen CA, Oudesluys-Murphy AM, Hop WC. Serum sodium levels and probability of recurrent febrile convulsions. Eur J Pediatr 1995; 154(5): 403-5.
Miceli Sopo S, Cuomo B, Federico G, Avantaggiato MD, Pugliese A, Navarra PL, et al. In vivo and in vitro production of interleukin-1 after febrile convulsions. Pediatr Med Chir 2001; 23(2): 83-7.
American Academy of Pediatrics. Practice parameter: the neurodiagnostic evaluation of the child with a first simple febrile seizure. Provisional Committee on Quality Improvement, Subcommittee on Febrile Seizures. Pediatrics 1996; 97(5): 769-72.
Thoman JE, Duffner PK, Shucard JL. Do serum sodium levels predict febrile seizure recurrence within 24 hours? Pediatr Neurol 2004; 31(5): 342-4.
Rutter N, O'Callaghan MJ. Hyponatraemia in children with febrile convulsions. Arch Dis Child 1978; 53(1): 85-7.
Dunlop S, Taitz J. Retrospective review of the management of simple febrile convulsions at a tertiary paediatric institution. J Paediatr Child Health 2005; 41(12): 647-51.
Rutter N, Smales OR. Role of routine investigations in children presenting with their first febrile convulsion. Arch Dis Child 1977; 52(3): 188-91.
Scarfone RJ, Pond K, Thompson K, Fall I. Utility of laboratory testing for infants with seizures. Pediatr Emerg Care 2000; 16(5): 309-12.
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Issue | Vol 47, No 3 (2009) | |
Section | Original Article(s) | |
Keywords | ||
Febrile convulsion recurrence sodium calcium electrolytes |
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