Original Article

The Role of Socio-economic Indicators in the Causation of Coronary Artery Disease

Abstract

South Asian countries have a high prevalence of coronary heart disease (CAD) in line with their economic development. In these countries, we find nearly one quarter of the total world population in the process of nutritional transition, from poverty to affluence due to rapid economic development. India; in particular, with a population of over one billion has a high burden of CAD. To evaluate the role of socio-economic and demographic variables on the coronary artery disease. A hospital based case-control study was conducted to investigate the role of social related risk factors on coronary artery disease (CAD) in an urban area of East Delhi from April 2002 to December 2004. To obtain more validate comparisons, a control group also was selected from community of East Delhi. The tools of enquiry were a pre-tested and pre-coded questionnaire, physical examination and laboratory testes. A confidence level of 95% and study power of 80% were considered for the interpretation of possible significant findings. Sexwise stratified analysis was separately done for male and female subjects. Comparison of male cases with their counterparts in both control groups indicated that the majority of them had significantly a college education, higher monthly income, semi or full professional occupations and were living in families with size of more than 9. The similar results was found for female cases as that majority of them as compare to females in both control groups were literate, employed and belonging to families with income levels of more than RS.8000. In addition, belonging to religion other than Hindus was another significant variable that was accounted for as risk for getting CAD. Our findings indicate that both male and female cases belonging to high socio-economic classes had higher chance for getting CAD as compare to their counterparte.

Shaper AG, Pocock SJ, Walker M, Cohen NM, Wale CJ, Thomson AG. British Regional Heart Study: cardiovascular risk factors in middle-aged men in 24 towns. Br Med J (Clin Res Ed) 1981; 283(6285): 179-86.

Kaplan GA, Keil JE. Socioeconomic factors and cardiovascular disease: a review of the literature. Circulation 1993; 88(4 Pt 1): 1973-98.

Pradeepa R, Deepa R, Rani SS, Premalatha G, Saroja R, Mohan V. Socioeconomic status and dyslipidaemia in a South Indian population: the Chennai Urban Population Study (CUPS 11). Natl Med J India 2003; 16(2): 73-8.

Fernández-Jarne E, Martínez-Losa E, Prado-Santamaría M, Brugarolas-Brufau C, Serrano-Martínez M, Martínez- González MA. Risk of first non-fatal myocardial infarction negatively associated with olive oil consumption: a casecontrol study in Spain. Int J Epidemiol 2002; 31(2): 474-80.

Kawachi I, Sparrow D, Spiro A 3rd, Vokonas P, Weiss ST. A prospective study of anger and coronary heart disease. The Normative Aging Study. Circulation 1996; 94(9): 2090-5.

Black JW, Stephenson JS. Pharmacology of a new adrenergic beta-receptor-blocking compound (Nethalide). Lancet 1962; 2(7251): 311-4.

Chadha SL, Radhakrishnan S, Ramachandran K, Kaul U, Gopinath N. Epidemiological study of coronary heart disease in urban population of Delhi. Indian J Med Res 1990; 92: 424-30.

Singh RB, Niaz MA, Thakur AS, Janus ED, Moshiri M. Social class and coronary artery disease in a urban populationof North India in the Indian Lifestyle and Heart Study. Int J Cardiol 1998; 64(2): 195-203.

Singh RB, Tomlinson B, Thomas GN, Sharma R. Coronary heart disease and coronary risk factors: The South Asian paradox. J Nutr Environ Med 2001; 11: 43-51.

Pais P, Pogue J, Gerstein H, Zachariah E, Savitha D, Jayprakash S, et al. Risk factors for acute myocardial infarction in Indians: a case-control study. Lancet 1996; 348(9024): 358-63.

Gupta R, Singhal S. Coronary heart disease in India. Circulation 1997; 96(10): 3785.

Reddy KS, Yusuf S. Emerging epidemic of cardiovascular disease in developing countries. Circulation 1998; 97(6): 596-601.

Whitty CJ, Brunner EJ, Shipley MJ, Hemingway H, Marmot MG. Differences in biological risk factors for cardiovascular disease between three ethnic groups in the WhitehallII study. Atherosclerosis 1999; 142(2): 279-86.

Vardan S, Mookherjee S, Vardan S, Sinha AK. Specialfeatures of coronary heart disease in people of the Indiansub-continent. Indian Heart J 1995; 47(4): 399-407.

Sethi KK, editor. Coronary Artery Disease in Indians: a Global Perspective. Mumbai: Cardiological Society of India; 1998.

Gupta R, Gupta VP, Ahluwalia NS. Educational status, coronary heart disease, and coronary risk factor prevalence in a rural population of India. BMJ 1994; 309(6965): 1332-6.

Bagchi S, Biswas R, Bhadra UK, Roy A, Mundle M, Dutta PK. Smoking, alcohol consumption and coronary heart disease:a risk factor study. Indian J Commun Med 2001; 26(4): 208-11.

Krishnaswami S. Observations on serial changes in coronaryartery disease in Indians. Curr Sci 1998; 74(12): 1064-8.

Pekkanen J, Uutela A, Valkonen T, Vartiainen E, Tuomilehto J, Puska P. Coronary risk factor levels: differences between educational groups in 1972-87 in eastern Finland. J Epidemiol Community Health 1995; 49(2): 144-9.

Tenconi MT, Devoti G, Comelli M. Socioeconomic indicators and mortality for ischemic cardiopathy in the RIFLE population; The RIFLE Group: Risk Factors and Life Expectancy. G Ital Cardiol 1999; 29(6): 698-704.

Reddy KK, Rao AP, Reddy TP. Socioeconomic status and the prevalence of coronary heart disease risk factors. Asia Pac J Clin Nutr 2002; 11(2): 98-103.

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IssueVol 47, No 4 (2009) QRcode
SectionOriginal Article(s)
Keywords
SES CAD Risk factors Case-Control study urban areas Delhi India

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How to Cite
1.
Lotfi MH, Tupil Kannan A, Dwivedi S, Sundaram Kiram R. The Role of Socio-economic Indicators in the Causation of Coronary Artery Disease. Acta Med Iran. 1;47(4):301-307.