Prevalence and Risk Factors of Erectile Dysfunction in Iranian Diabetic Men
,
Abstract
Erectile dysfunction (ED) is an important impediment to quality of life. Diabetes mellitus is one of the most common causes of ED. However, it has been one of the most neglected complications of diabetes mellitus. Our objective was to study the prevalence of ED and its risk factors in Iranian diabetic men. During 2002-2004, 700 diabetic men aged 20-69 years were interviewed to report on their experience of ED as defined in the National Institutes of Health Consensus Conference 1993. ED was found in 246 (35.1%) of this population. Prevalence of ED was increased with age from 9.7% in men aged 20-39 years to 43.4% in those aged over 60 years (P < 0.001). Men with type I diabetes reported ED less frequently than did men with type II diabetes (P = 0.037). In comparison with patients with reported diabetes lasting ≤ 5 years (25.4%), the prevalence of ED was less than in those with diabetes of 6-11 years (34.3%) and of 12-30 years (43.5%, P < 0.001). ED increased significantly in those who had poor glycemic control. Prevalence of ED in patients with good, fair and poor glycemic control was 28.4%, 39.9% and 44.4% respectively (P = 0.004). Type of treatment (diet alone, oral agents, insulin and insulin plus oral agents) had significant association with ED and its severity (P < 0.001). ED is common in Iranian diabetic men but its prevalence can be reduced with good glycemic control.
Beutel ME, Weidner W, Brähler E. Epidemiology of sexual dysfunction in the male population. Andrologia 2006; 38(4): 115-21.
Pegge NC, Twomey AM, Vaughton K, Gravenor MB, Ramsey MW, Price DE. The role of endothelial dysfunction in the pathophysiology of erectile dysfunction in diabetes and in determining response to treatment. Diabet Med 2006; 23(8): 873-8.
Rance J, Phillips C, Davies S, O'Malley B, Zaman Q, Price D. How much of a priority is treating erectile dysfunction? A study of patients' perceptions. Diabet Med 2003; 20(3): 205-9.
Ferro A. Erectile dysfunction in diabetes: 'NO' role for themendothelium? Int J Clin Pract 2006; 60(10): 1154-5.
Cartledge JJ, Eardley I, Morrison JF. Nitric oxide-mediated corpus cavernosal smooth muscle relaxation is impaired in ageing and diabetes. BJU Int 2001; 87(4): 394-401.
Browne DL, Meeking DR, Allard S, Munday LJ, Shaw KM, Cummings MH. Diabetic erectile dysfunction: an indicator of generalised endothelial function per se? Int J Clin Pract n2006; 60(10): 1323-6.
Siu SC, Lo SK, Wong KW, Ip KM, Wong YS. Prevalencenof and risk factors for erectile dysfunction in Hong Kongndiabetic patients. Diabet Med 2001; 18(9): 732-8.
Bacon CG, Hu FB, Giovannucci E, Glasser DB, Mittleman MA, Rimm EB. Association of type and duration of diabetes with erectile dysfunction in a large cohort of men. Diabetes Care 2002; 25(8): 1458-63.
Rosen RC, Cappelleri JC, Gendrano N 3rd. The International Index of Erectile Function (IIEF): a state-of-thesciencereview. Int J Impot Res 2002; 14(4): 226-44.
Kuzuya T, Nakagawa S, Satoh J, Kanazawa Y, Iwamoto Y, Kobayashi M, et al. Report of the Committee on the classification and diagnostic criteria of diabetes mellitus. Diabetes Res Clin Pract 2002; 55(1): 65-85.
Bacon CG, Hu FB, Giovannucci E, Glasser DB, Mittleman MA, Rimm EB. Association of type and duration of diabetes with erectile dysfunction in a large cohort of men. Diabetes Care 2002; 25(8): 1458-63.
Fedele D, Coscelli C, Santeusanio F, Bortolotti A, Chatenoud L, Colli E, et al. Erectile dysfunction in diabetic subjects in Italy. Gruppo Italiano Studio Deficit Erettile nei Diabetici. Diabetes Care 1998; 21(11): 1973-7.
Safarinejad MR. Prevalence and risk factors for erectile dysfunction in a population-based study in Iran. Int J Impot Res 2003; 15(4): 246-52.
Rubin A, Babbott D. Impotence and diabetes mellitus. J Am Med Assoc 1958; 168(5): 498-500.
Schoffling K. Storungen der keimdrusentunktion ber mannlichen zuckerkranken. Beitruge zur sexua torschung 1958; 19: 1-83.
Montenero P, Donatone E. Preliminary results on the gentamicin effect in the urinary tract infections of diabetic subjects. G Ital Chemioter 1969; 16(1): 130-2.
Ellenberg M. Impotence in diabetes: the neurologic factor. Ann Intern Med 1971; 75(2): 213-9.
Faerman I, Vilar O, Rivarola MA, Rosner JM, Jadzinsky MN, Fox D, et al. Impotence and diabetes. Studies of androgenic function in diabetic impotent males. Diabetes 1972; 21(1): 23-30.
Kolodny RC, Kahn CB, Goldstein HH, Barnett DM. Sexual dysfunction in diabetic men. Diabetes 1974; 23(4): 306-9.
Neubauer M, Schoffling K. Sexualstorungen bei diabetischen mannern. In: Oberdisse K, editor. Handbuch Der Inneren Medizin. 7/2B: Diabetes Mellitus. Berlin: Heidelberg, New York: Springer; 1977. p. 465-505.
Lester E, Grant AJ, Woodroffe FJ. Impotence in diabetic and non-diabetic hospital outpatients. Br Med J 1980; 281(6236): 354-5.
McCulloch DK, Campbell IW, Wu FC, Clarke B, Prescott RJ. Impotence in diabetic and non-diabetic hospital outpatients. Br Med J 1980; 281(6249): 1216.
Nathan DM, Singer DE, Godine JE, Perlmuter LC. Noninsulin- dependent diabetes in older patients. Complications and risk factors. Am J Med 1986; 81(5): 837-42.
Cavan DA, Barnett AH, Leatherdale BA. Diabetic impotence: risk factors in a clinic population. Diabetes Res 1987; 5(3): 145-8.
Modebe O. Erectile failure among medical clinic patients. Afr J Med Med Sci 1990; 19(4): 259-64.
Feldman HA, Goldstein I, Hatzichristou DG, Krane RJ, McKinlay JB. Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. J Urol 1994; 151(1): 54-61.
Brunner GA, Pieber TR, Schattenberg S, Ressi G, Wieselmann G, Altziebler S, et al. Erectile dysfunction in patients with type I diabetes mellitus. Wien Med Wochenschr 1995; 145(21): 584-6.
Klein R, Klein BE, Lee KE, Moss SE, Cruickshanks KJ. Prevalence of self-reported erectile dysfunction in people with long-term IDDM. Diabetes Care 1996; 19(2): 135-41.
Bortolotti A, Parazzini F, Colli E, Landoni M. The epidemiology of erectile dysfunction and its risk factors. Int J Androl 1997; 20(6): 323-34.
William A. The management of erectile dysfunction associated with diabetes. Sex Dys 1998; 1: 113-8.
El-Sakka AI, Tayeb KA. Erectile dysfunction risk factors in noninsulin dependent diabetic Saudi patients. J Urol 2003; 169(3): 1043-7.
Romeo JH, Seftel AD, Madhun ZT, Aron DC. Sexual function in men with diabetes type 2: association with glycemic control. J Urol 2000; 163(3): 788-91.
Virag R, Bouilly P, Frydman D. Is impotence an arterial disorder? A study of arterial risk factors in 440 impotent men. Lancet 1985; 1(8422): 181-4.
Condra M, Morales A, Owen JA, Surridge DH, Fenemore J. Prevalence and significance of tobacco smoking in impotence. Urology 1986; 27(6): 495-8.
Shabsigh R, Fishman IJ, Schum C, Dunn JK. Cigarette smoking and other vascular risk factors in vasculogenic impotence. Urology 1991; 38(3): 227-31.
| Files | ||
| Issue | Vol 47, No 4 (2009) | |
| Section | Articles | |
| Keywords | ||
| Diabetes mellitus erectile dysfunction prevalence risk factors | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
