Influence of Physiological Factors on Thyroid Size Determined by Ultrasound


According to its superficial anatomical location, the thyroid gland is easily accessible by sonography. Sonography allows an exact documentation of the size and thyroid volume. The relationship between thyroid volume and anthropometric characteristics is a matter of controversy. The aim of this study was to investigate thyroid volume and its determinants in healthy adult. A cross-sectional study was performed from June2003 until April 2005 in 314 healthy adults aged over 18 years old in Yazd, Iran. Data were collected on age, sex, and weight and thyroid size by sonoraphy. Mean of thyroid volume in male and female was 9.08 ± 2.49 and 7.93 ± 3.2 milliliter which the differences was significant (P<0.003).Differences between thyroid volume and weight was significant (P=0.001). Mean of female weight and proportion of thyroid volume to their weight was 61.83 ± 12.09kg and 0.130 ± 0.33. Mean of male weight and proportion of thyroid volume to their weight was 71.41 ± 9.05kg and 0.126 ± 0.028 (P<0.003). Results of study is similar to other studies .Mean of thyroid volume in Yazd citizens is not differ from other Iranian but is different from other countries. This difference could be related to food intake habit, geographical region and daily oral iodine consumption

Wiesner W, Engel H, Steinbrich W, Oertli D. Sonography of the thyroid. Praxis (Bern 1994) 2006;95(15):575-80.

Hegedüs L. Thyroid ultrasound. Endocrinol Metab Clin North Am 2001;30(2):339-60.

Gimondo P, Mirk P, Messina G, Pizzi G, Tomei A. The role of ultrasonography in thyroid disease. Minerva Med 1993;84(12):671-80.

Foo LC, Zulfiqar A, Nafikudin M, Fadzil MT, Asmah AS. Local versus WHO/International Council for Control of Iodine Deficiency Disorders-recommended thyroid volume reference in the assessment of iodine deficiency disorders. Eur J Endocrinol 1999;140(6):491-7.

Xu F, Sullivan K, Houston R, Zhao J, May W, Maberly G. Thyroid volumes in US and Bangladeshi schoolchildren: comparison with European schoolchildren. Eur J Endocrinol 1999;140(6):498-504.

Sari R, Balci MK, Altunbas H, Karayalcin U. The effect of body weight and weight loss on thyroid volume and function in obese women. Clin Endocrinol (Oxf) 2003;59(2):258-62.

Wesche MF, Wiersinga WM, Smits NJ. Lean body mass as a determinant of thyroid size. Clin Endocrinol (Oxf) 1998;48(6):701-6.

Mozaffari Khosravi H, Dehghani A, Afkhami M. Prevalence of endemic goiter and urinary iodine in 6-11 year old students in Yazd province: 10 years after salt iodization programme. Iranian J Endocl Metab 2004;5(4):283-91.

Berghout A, Wiersinga WM, Smits NJ, Touber JL. The value of thyroid volume measured by ultrasonography in the diagnosis of goitre. Clin Endocrinol (Oxf) 1988;28(4):409-14.

Azizi F, Delshad H, Mehrabi Y. Thyroid volumes in schoolchildren of Tehran: comparison with European schoolchildren. J Endocrinol Invest 2001;24(10):756-62.

Azizi F, Malik M, Bebars E, Delshad H, Bakir A. Thyroid volumes in schoolchildren of the Emirates. J Endocrinol Invest 2003;26(1):56-60.

Tajtáková M, Langer P, Gonsorcíková V, Bohov, Hancinová D. Recognition of a subgroup of adolescentswith rapidly growing thyroids under iodine-replete conditions: seven year follow-up. Eur J Endocrinol 1998;138(6):674-80.

Müller-Leisse C, Tröger J, Khabirpour F, Pöckler C. Normal values of thyroid gland volume. Ultrasound measurements in schoolchildren 7 to 20 years of age. Dtsch Med Wochenschr 1988;113(48):1872-5.

IssueVol 49, No 5 (2011) QRcode
Thyroid volume Sonography Body mass index Age Sex

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
Nafisi Moghadam R, Shajari A, Afkhami-Ardekani M. Influence of Physiological Factors on Thyroid Size Determined by Ultrasound. Acta Med Iran. 49(5):302-304.