Relationship between the Pattern of Coronary Artery Disease Risk Factors and Lipid Ratios with Five Groups of Body Mass Index in 28566 Healthy Adults

  • Zinat Nadia Hatmi Mail Department of Social Medicine, Tehran University of Medical Sciences, Tehran, Iran.
  • Mitra Mahdavi-Mazde Department of Nephrology, Tehran University of Medical Sciences, Tehran, Iran.
  • Seyed Saeid Hashemi-Nazari Health City Office, Tehran Municipality, Tehran, Iran.
  • Ebrahim Hajighasemi Health City Office, Tehran Municipality, Tehran, Iran.
  • Behnaz Nozari Research Center of Iranian Tissue Bank, Tehran, Iran.
  • Nasrin Jalilian Department of Obstetric and Gynecology, Kermanshah University of Medical Sciences, Kermanshah, Iran.
  • Azita Mahdavi National Behzisti Organization, Tehran, Iran.
Keywords:
Coronary artery disease, Risk assessment, Body mass index, Lipid ratios

Abstract

Pattern of the coronary artery disease (CAD) risk factors across body mass index (BMI) categories remains uncertain. There is a different threshold of obesity for increasing cardiovascular hazard across populations, accordingly recognition and management of obesity and overweight can guide better control of CAD epidemic in the national level. To determine the discrepancy in the prevalence of CAD risk factors across five BMI categories. A population based survey of 28566 participants recruited to medical screening of taxi drivres in Tehran (MSTDT) was designed. According to a standardized protocol data on CAD risk factors were obtained by taking medical history, examination and laboratory tests. After adjustment for age, sex, literacy, smoking, systolic blood pressure (SBP), fasting blood sugar (FBS), and LDL-C/HDL-C ratio, these CAD risk factors of diastolic blood pressure (DBP)>90 mmHg, hypertriglyceridemia, high triglyceride/ HDL-C ratio, hypercholesterolemia, and high cholesterol/HDL-C ratio were increased significantly across five incremental categories of BMI. Prevalence of DBP> 90 mmHg, hypertriglyceridemia, hyper cholesterolemia and ratios of cholesterol/ HDL-C and TG/HDL-C increased considerably across five groups of BMI. This pattern is different from previous research and our results endorsed more features of pattern of CAD risk factors across BMI categories.

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How to Cite
1.
Hatmi ZN, Mahdavi-Mazde M, Hashemi-Nazari SS, Hajighasemi E, Nozari B, Jalilian N, Mahdavi A. Relationship between the Pattern of Coronary Artery Disease Risk Factors and Lipid Ratios with Five Groups of Body Mass Index in 28566 Healthy Adults. Acta Med Iran. 49(11):730-736.
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