Substance Abuse Disorders in the Parents of ADHD Children, and Parents of Normal Children

  • Farideh Farokhzadi Mail Department of Psychology, Payame Nour University of Medical Sciences, Tehran, Iran.
  • Mohammad Reza Mohammadi Psychiatry and Psychology Research Center, Tehran University of Medical sciences, Tehran, Iran.
  • Ahmad Alipour Department of Psychology, Payame Nour University, Tehran, Iran.
  • Reza Rostami Department of Psychiatry, Tehran University of Medical Sciences, Tehran, Iran.
  • Mehdi Dehestani Department of Psycho-Pathology, Payame Nour University, Tehran, Iran.
Attention-deficit/ hyperactivity disorder (ADHD), Adolescents, Children, Normal children, Parents and substance abuse disorder


The objective of the study was to compare the attention-deficit/ hyperactivity, and substance abuse disorders background in the parents of children with attention-deficit/ hyperactivity disorder (ADHD), and the parents of normal children. The available sampling method was used to choose 400 parents of children (200 parents of children with ADHD and 200 parents of normal children), the ages of children were 6-18 years old. The data were collected through the Schedule for Affective Disorders and Schizophrenia (SADS) for parents and the Kiddy Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version (K-SADS-PL), Connors Adult ADHD Rating Scale (CAARS) and the Wender Utah Rating Scale (WURS) for adult ADHD. The results were analyzed by using SPSS-17 software, based on two-variable Chi-Square and t-tests.and P value in all disorders were equals to P<0.05. The results indicated that substance abuse in parents of children with ADHD is 21% more prevalent, and parents of children with ADHD compared to parents of normal children have 2% ADHD, 9% attention deficit disorder, and 1% hyperactivity disorder more in their background. Therefore, we conclude that there exists a significant difference between the above mentioned disorders in the parents of children with ADHD, and parents of normal children. The high prevalence rate of disorders and background of ADHD in families of individuals with ADHD shows the probability of effect of inheritance in the disorder. Also, it shows that parents of children with ADHD have more substance abuse and history of ADHD in their background.


Yousefi Sh, Soltanifar A, Teymori S. The comparison of maternity tention of ADHD children with mothers of normal children. J Mental Health Principles 2009;11(2):115-22. [Persian]

Johnston C, Mash EJ. Families of children with attentiondeficit/ hyperactivity disorder: review and recommendations for future research. Clin Child Fam Psychol Rev 2001;4(3):183-207.

Biederman J, Faraone SV, Keenan K, Benjamin J, Krifcher B, Moore C, Sprich-Buckminster S, Ugaglia K, Jellinek MS, Steingard R, et al. Further evidence for family-genetic risk factors in attention deficit hyperactivity disorder. Patterns of comorbidity in probands and relatives psychiatrically and pediatrically referred samples. Arch Gen Psychiatry 1992;49(9):728- 38.

Biederman J, Faraone SV, Keenan K, Knee D, Tsuang MT. Family-genetic and psychosocial risk factors in DSM-III attention deficit disorder. J Am Acad Child Adolesc Psychiatry 1990;29(4):526-33.

Faraone SV, Biederman J, Milberger S. An exploratory study of ADHD among second-degree relatives of ADHD children. Biol Psychiatry 1994;35(6):398-402.

Janatian S, Nouri A, Shafti A, Molavi H, Samavatyan H.Effectiveness of play therapy on the bases of cognitive behavior approach on severity of symptoms of Attention Deficit/Hyperactivity Disorder (ADHD) among primary school male students aged 9-11. Behav Sci Res 2008;6(2):109-18.

Smalley SL, McGough JJ, Del'Homme M, NewDelman J, Gordon E, Kim T, Liu A, McCracken JT. Familial clustering of symptoms and disruptive behaviors in multiplex families with attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 2000;39(9):1135-43.

Dulcan M. Practice parameters for the assessment and treatment of children, adolescents, and adults with attention-deficit/hyperactivity disorder. American Academy of Child and Adolescent Psychiatry. J Am Acad Child Adolesc Psychiatry 1997;36(10 Suppl):85S-121S.

Biederman J, Munir K, Knee D, Habelow W, Armentano M, Autor S, Hoge SK, Waternaux C. A family study of patients with attention deficit disorder and normal controls. J Psychiatr Res 1986;20(4):263-74.

Biederman J, Petty CR, Ten Haagen KS, Small J, Doyle AE, Spencer T, Mick E, Monuteaux MC, Smoller JW, Faraone SV. Effect of candidate gene polymorphisms on the course of attention deficit hyperactivity disorder. Psychiatry Res 2009;170(2-3):199-203.

Biederman J, Faraone SV, Keenan K, Steingard R, Tsuang MT. Familial association between attention deficit disorder and anxiety disorders. Am J Psychiatry 1991;148(2):251-6.

Sadock BJ, Sadock VA, editors. Kaplan and Sadock's Comprehensive Textbook of Psychiatry. 7th ed. Philadelphia, PA: Lippincott Williams and Wilkins; 2000. p. 2679-93.

Ambrosini PJ. Historical development and present status of the schedule for affective disorders and schizophrenia for school-age children (K-SADS). J Am Acad Child Adolesc Psychiatry 2000;39(1):49-58.

Khoshabi K, Mirabzadeh A, Moradi S, Gilanipour M. The role of behavioral factors and other risk factors in children with attention deficit hyperactivity disorder. J Hamadan Univ Med Sci 2008;14(2):11-5. [Persian]

Sadock BJ, Sadock VA. Kaplan and Sadock's Synopsis of Psychiatry: Behavioral Sciences/Clinical Psychiatry. 10th ed. Philadelphia, PA: Lippincott Williams and Wilkins; 2007.

Abedi S, Shirazi E, Hajebi A. Is ADHD more prevalent is substance users? Iran J Clin Psychol Psychiatr Soc 2007;13(3):227-31. [Persian]

Biederman J, Faraone SV, Keenan K, Tsuang MT. Evidence of familial association between attention deficit disorder and major affective disorders. Arch Gen Psychiatry 1991;48(7):633-42.

Faraone SV, Biederman J, Chen WJ, Milberger S, Warburton R, Tsuang MT. Genetic heterogeneity in attention-deficit hyperactivity disorder (ADHD): gender, psychiatric comorbidity, and maternal ADHD. J Abnorm Psychol 1995;104(2):334-45.

Biederman J, Petty CR, Wilens TE, Fraire MG, Purcell CA, Mick E, Monuteaux MC, Faraone SV. Familial risk analyses of attention deficit hyperactivity disorder and substance use disorders. Am J Psychiatry 2008;165(1):107-15.

Disney ER, Elkins IJ, McGue M, Iacono WG. Effects of ADHD, conduct disorder, and gender on substance use and abuse in adolescence. Am J Psychiatry 1999;156(10):1515-21.

Biederman J, Wilens T, Mick E, Faraone SV, Weber W, Curtis S, Thornell A, Pfister K, Jetton JG, Soriano J. Is ADHD a risk factor for psychoactive substance use disorders? Findings from a four-year prospective followup study. J Am Acad Child Adolesc Psychiatry 1997;36(1):21-9.

Wilens TE. Attention-deficit/hyperactivity disorder and the substance use disorders: the nature of the relationship, subtypes at risk, and treatment issues. Psychiatr Clin North Am 2004;27(2):283-301.

Wilens TE, Vitulano M, Upadhyaya H, Adamson J, Sawtelle R, Utzinger L, Biederman J. Cigarette smoking associated with attention deficit hyperactivity disorder. J Pediatr 2008;153(3):414-9.

Monuteaux MC, Faraone SV, Hammerness P, Wilens TE, Fraire M, Biederman J. The familial association between cigarette smoking and ADHD: a study of clinically referred girls with and without ADHD, and their families. Nicotine Tob Res 2008;10(10):1549-58.

Lindblad F, Hjern A. ADHD after fetal exposure to maternal smoking. Nicotine Tob Res 2010;12(4):408-15.

Goyette CH, Conners CK, Ulrich RF. Normative data on revised Conners Parent and Teacher Rating Scales. J Abnorm Child Psychol 1978;6(2):221-36.

Ward MF, Wender PH, Reimherr FW. The Wender Utah Rating Scale: an aid in the retrospective diagnosis of childhood attention deficit hyperactivity disorder. Am J Psychiatry 1993;150(6):885-90. Erratum in: Am J Psychiatry 1993;150(8):1280.

Retz-Junginger P, Retz W, Blocher D, Stieglitz RD, Georg T, Supprian T, Wender PH, Rösler M. Reliability and validity of the Wender-Utah-Rating-Scale short form. Retrospective assessment of symptoms for attention deficit/hyperactivity disorder. Nervenarzt 2003;74(11): 987-93

Schachar R, Wachsmuth R. Hyperactivity and parental psychopathology. J Child Psychol Psychiatry 1990;31(3):381-92.

Biederman J, Petty CR, Monuteaux MC, Mick E, Clarke A, Ten Haagen K, Faraone SV. Familial risk analysis of the association between attention-deficit/hyperactivity disorder and psychoactive substance use disorder in female adolescents: a controlled study. J Child Psychol Psychiatry 2009;50(3):352-8.

How to Cite
Farokhzadi F, Mohammadi MR, Alipour A, Rostami R, Dehestani M. Substance Abuse Disorders in the Parents of ADHD Children, and Parents of Normal Children. Acta Med Iran. 50(5):319-327.