Incidence of Intraventricular Hemorrhage and Post Hemorrhagic Hydrocephalus in Preterm Infants

  • Negar Sajjadian Mail Department of Neonatology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Hossein Fakhrai Department of Neonatology, Mofid Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Ramin Jahadi Department of Neonatology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Keywords:
Hemorrhage, cerebral ventricles, hydrocephalus, ultrasonography

Abstract

Germinal matrix-intraventricular hemorrhage (IVH) is the most common variety of neonatal intracranial hemorrhage and is characteristics of the premature infant. The importance of the lesion relates not only to its high incidence but to their attendant complications (IC: hydrocephalus). Brain sonography is the procedure of choice in diagnosis of germinal matrix- intraventricular hemorrhage and hydrocephalus. In this study we have used brain sonography for detection of intraventricular hemorrhage and post hemorrhagic hydrocephalus and their incidences. The studied population was consisted of premature neonate (birth weight equal or less than 1500g and gestational age equal or less than 37 weeks) who admitted in Mofid Hospital NICU (Tehran, Iran) during a one year period. For all neonate (including criteria) brain sonography in first week of life was done and in presence of IVH, serial Brain sonography was done weekly for detection of hydrocephalus. A total of 57 neonate entered the study. Intraventicular-germinal matrix hemorrhage was seen in 64.4% (35 patients). Forty percent of patients with intraventricular-germinal matrix hemorrhage had grade I, 11% grade II, 25.7% grade III, 2.8% grade VI. Hydrocephalus was detected in 20 percent of patients who had intraventricular-germinal matrix hemorrhage. That incidence of IVH in our study in comparison with other area and situation is higher. Hydrocephaly had direct relation with severity of IVH. This shows that with control of risk factor of IVH, we can control Post hemorrhagic hydrocephalus.

References

Volpe JJ. Neurology of the Newborn. 4th ed. Philadelphia: WB Saunders Co; 2000. p. 428.

Sheth RD. Trends in incidence and severity of intraventricular hemorrhage. J Child Neurol 1998;13(6):261-4.

Perlman JM, Volpe JJ. Intraventricular hemorrhage in extremely small premature infants. Am J Dis Child 1986;140(11):1122-4.

Volpe JJ. Intraventricular hemorrhage and brain injury in the premature infant. Diagnosis, prognosis, and prevention. Clin Perinatol 1989;16(2):387-411.

Toi A, Sauerbrei EE. The fetal brain. In: Rumack CM, Wilson SR, Charboneau JW, editors. Diagnostic Ultrasound. 2nd ed. St. Louis: Mosby Year Book; 1998. p. 12.

Rumack CM, Manco-Johnson ML, Manco-Johnson MJ, Koops BL, Hathaway WE, Appareti K. Timing and course of neonatal intracranial hemorrhage using real-time ultrasound. Radiology 1985;154(1):101-5.

Antoniuk S, da Silva RV. Periventricular and intraventricular hemorrhage in the premature infants. Rev Neurol 2000;31(3):238-43.

Mancini MC, Barbosa NE, Banwart D, Silveira S, Guerpelli JL, Leone CR. Intraventricular hemorrhage in very low birth weight infants: associated risk factors and outcome in the neonatal period. Rev Hosp Clin Fac Med Sao Paulo 1999;54(5):151-4.

Alvarez MD, Villamil M, Reyes G. Predictive factors in the genesis of intraventricular hemorrhage in premature infants. P R Health Sci J 1994;13(4):251-4.

Linder N, Haskin O, Levit O, Klinger G, Prince T, Naor N, et al. Risk factors for intraventricular hemorrhage in very low birth weight premature infants: a retrospective casecontrol study. Pediatrics 2003;111(5 Pt 1):e590-5.

Dykes FD, Dunbar B, Lazarra A. Posthemorrhagic hydrocephalus in high-risk preterm infants: natural history, management, and long-term outcome. J Pediatr 1989;114(4 Pt 1):611-8.

Slabaugh RD, Smith JA, Lemons J, Schreiner R, Macdonald N, Cohen MD. Neonatal intracranial hemorrhage and complicating hydrocephalus. J Clin Ultrasound 1984;12(5):261-6.

How to Cite
1.
Sajjadian N, Fakhrai H, Jahadi R. Incidence of Intraventricular Hemorrhage and Post Hemorrhagic Hydrocephalus in Preterm Infants. Acta Med Iran. 48(4):260-262.
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Articles