Two Cases of Polycystic Kidneys in Two Siblings

Abstract

Polycystic disease of th e kidneys is a genetalized lesion o f charact erist ic clinico-pathological enti ty. It has two c1in cial fo rms: adult and infantile . The adult type is transmitted as a dominan t disease where the latter is a recessive trait. The infantile form had two pathological patterns, Form "A" in which the kidney is large and spo ngy , of normal shape and the cyst s are numerous. Microscopically the co nnective tissue is not increased. The cysts are of eq ual size and shape. The ncph rons are not reduced . In th e form "B" t he kidney may not have a normal shape and is not as large as the form "A" . Microscopica ll y the connect ive t issue is increased intensively. The cysts are of spherical shape and different sizes. The nephrons are reduced in number.