Hypothalamic Hamartoma in An Unusual Case with Delayed Puberty

  • Maryam Nakhaeimoghadam Research Center for Children and Adolescents Health, Zahedan University of Medical Sciences, Zahedan, Iran.
  • Parastoo Rostami Department of Pediatric Endocrinology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Ameneh Zare-Shahabadi Students’ Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Mehrzad Mehdizadeh Department of Pediatric Radiology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Ali Rabbani Department of Pediatric Endocrinology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran. AND Growth and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Nima Rezaei Mail Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran. AND Molecular Immunology Research Center; and Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Keywords:
Delay in puberty, Hypothalamic hamartomas, Magnetic resonance imaging

Abstract

Hypothalamic hamartoma (HH) is a rare intracranial lesion that usually presents with classic triad of central precocious puberty, gelastic epilepsy, and developmental delay. Herein, a 14-year old boy is presented in whom the diagnosis of HH was made by magnetic resonance imaging. While he did not have any complain of precocious puberty, he surprisingly suffered from delay in puberty. The definite diagnosis of HH can only be made by appropriate imaging, in a case with atypical feature of delay in puberty and in the absence of gelastic epilepsy. To our best knowledge, this is the first case of HH who is presented with delay in puberty as of first manifestation.

References

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How to Cite
1.
Nakhaeimoghadam M, Rostami P, Zare-Shahabadi A, Mehdizadeh M, Rabbani A, Rezaei N. Hypothalamic Hamartoma in An Unusual Case with Delayed Puberty. Acta Med Iran. 51(11):819-821.
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