Intestinal Tuberculosis Sometimes Mimics Crohn's Disease

  • Esfandiar Shojaei Mail Department of Infectious Diseasses, Tehran University of Medical Sciences, Tehran, Iran.
  • Zahra Abdi Layali Department of Infectious Diseasses, Tehran University of Medical Sciences, Tehran, Iran.
  • Sirous Faraji Hormozi Department of Infectious Diseases, Army University of Medical Sciences, Tehran, Iran.
  • Pardis Moradnejad Department of Infectious Diseasses, Tehran University of Medical Sciences, Tehran, Iran.
Crohn`s Disease, Small intestine, Tuberculosis


Intestinal tuberculosis is an uncommon presentation of tuberculosis (TB) and has clinicopathological similarities with Crohn's disease. In regions where TB is endemic clinicians must aware of this condition and fully evaluate their patients when Crohn's disease is diagnosed. We recommend all pathologic specimens be evaluate effectively for TB.Smear, culture and PCR for Mycobacterium.tuberculosis from samples aside the pathological reviews help for better diagnosis. Here we present a case of intestinal tuberculosis which initially diagnosed as Crohn's disease but after starting immunosuppressive agents he presented with disseminated tuberculosis.


Epstein D, Watermeyer G, Kiresh R. The diagnosis and management of Crohn‘s disease in populations with high risk rates of Tuberculosis. Aliment Pharmacol Ther 2007;25(12):1373-88.

Sharma MP, Ahuja V. Abdominal (Gasterointestinal tract) tuberculosis in adults. In: Schaaf HS, Zumla A, editors. Tuberculosis .1st edition. Saunders 2009;424-30.

Massad J, Wehbi M, Klapproth JM. Anorectal Tuberculosis mimicking Crohn‘s disease. Clin Gastroenterol Hepatol 2008;6(2):e9.

Leung VK, Law ST, Lam CW, Luk IS, Chau TN, Loke TK, Chan WH, Lam SH. Intestinal tuberculosis in a regional hospital in Hong Kong: a 10-year experience. Hong Kong Med J 2006;12(4):264-71.

Sadasivan S, Raj VV, Narayanan VA, Dhor P, Mehta R, Nair P, Balakrishnan V. Clinicocolonoscopic differentiation of tuberculosis from Crohn‘s disease. Gasterointestinal Endoscopy 2005;61(5):1446-8.

Van Assche G, Dignass A, Panes J, Beaugerie L, Karagiannis J, Allez M, Ochsenkühn T, Orchard T, Rogler G, Louis E, Kupcinskas L, Mantzaris G, Travis S, Stange E; European Crohn's and Colitis Organisation (ECCO). The second European evidence-based consensus on the diagnosis and management of Crohn‘s disease: Definitions and Diagnosis. J Crohns Colitis 2010;4(1):7-27.

Alvarez JF, Devarbhaui H, Makhija P, Rao S, Kottoor R. Clinical, colonoscopic , and histological profile of colonic TB in a tertiary hospital. Endoscopy 2005;37(4):351-6.

How to Cite
Shojaei E, Abdi Layali Z, Faraji Hormozi S, Moradnejad P. Intestinal Tuberculosis Sometimes Mimics Crohn’s Disease. Acta Med Iran. 51(11):814-815.