Sleep Quality and Depression among Patients with Migraine

  • Khosro Sadeghniiat Center for Research on Occupational Diseases, Tehran University of Medical Sciences, Tehran, Iran.
  • Alaleh Rajabzadeh Mail Department of Neurology, Tehran University of Medical Sciences, Tehran, Iran.
  • Mahsa Ghajarzadeh Brain and Spinal Injury Research Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Majid Ghafarpour Department of Neurology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Keywords:
Depression, Migraine, Sleep quality

Abstract

The aim of this study was to determine the sleep quality and level of depression among Iranian migraineurs. Among 380 cases that were selected by simple random selection from those who attended Outpatient Neurology Clinic of Imam Khomeini Hospital, 332 patients participated in this cross-sectional study. After an inclusive examination by a neurologist, the participants were asked to fill valid and reliable Persian versions of Pittsburg Sleep Questionnaire (PSQI) and Beck Depression Inventory (BDI). They also requested to score headache severity by means of a visual analogue scale graded from 1-10. According to frequency of attacks, patients were divided into three groups: with 1-4 migraine days per month, 5-7 migraine days in a month and more than 7 migraine days per month. Mean age of participants was 36.3±10.1 years and mean headache severity score was 6.0±1.9. The PSQI total score and headache severity score were highest among patients with frequent attacks. Mean BDI, PSQI and headache severity scores significantly differ between male and female participants. There was significant positive correlation between BDI and PSQI scores (r=0.5, P<0.001) also there was a positive correlation between headache severity score and PSQI score (r=0.6, P<0.001). Decreased sleep quality with other co-morbidities such as depression in migraineurs cases should be considered.

References

Seidel S, Hartl T, Weber M, Matterey S, Paul A, Riederer F, Gharabaghi M, Wöber-Bingöl C, Wöber C. PAMINA Study Group. Quality of sleep, fatigue and daytime sleepiness in migraine- a controlled study. Cephalalgia 2009;29(6):662-9.

Vgontzas A, Cui L, Merikangas KR. Are Sleep Difficulties Associated With Migraine Attributable to Anxiety and Depression? Headache 2008;48(10):1451-9.

Kelman L, Rains JC. Headache and sleep: examination of sleep patterns and complaints in a large clinical sample of migraineurs. Headache 2005;45(7):904-10.

Alberti A. Headache and sleep. Sleep Med Rev 2006;10(6):431-7.

Rains JC, Poceta JS. Headache and sleep disorders: review and clinical implications for headache management. Headache 2006;46(9):1344-63.

Hsu SC, Wang SJ, Liu CY, Juang YY, Yang CH, Hung CI. The impact of anxiety and migraine on quality of sleep in patients with major depressive disorder. Compr Psychiatry 2009;50(2):151-7.

Giffin NJ, Ruggiero L, Lipton RB, Silberstein SD, Tvedskov JF, Olesen J, Altman J, Goadsby PJ, Macrae A. Premonitory symptoms in migraine. Neurology 2003;60(6):935-40.

Sahota P. Morning headaches in patients with sleep disorders. Sleep Med 2003;4(5):377.

Patel NV, Bigal ME, Kolodner KB, Leotta C, Lafata JE, Lipton RB. Prevalence and impact of migraine and probable migraine in a health plan. Neurology 2004;63(8):1432–8.

Wang SJ, Liu HC, Fuh JL, Liu CY, Wang PN, Lu SR. Comorbidity of headaches and depression in the elderly. Pain 1999;82(3):239-43.

Merikangas KR, Angst J, Isler H. Migraine and psychopatology. Results of Zurich cohort study of young adults. Arch Gen Psychiatry 1990;47(9):849-53.

Ghassemzadeh H, Mojtabai R, Karamghadiri N, Ebrahimkhani N. Psychometric properties of a Persianlanguage version of the Beck Depression Inventory-- Second edition: BDI-II-PERSIAN. Depress Anxiety 2005;21(4):185-92.

Farrahi Moghaddam J, Nakhaee N, Sheibani V, Garrusi B, Amirkafi A. Reliability and validity of the Persian version of the Pittsburgh Sleep Quality Index (PSQI-P). Sleep Breath 2011;16(1):79-82.

Gori S, Morelli N, Maestri M, Fabbrini M, Bonanni E, Murri L. Sleep quality, chronotypes and preferential timing of attacks in migraine without aura. J Headache Pain 2005;6(4):258-60.

Peres MF, Zukerman E, Young WB, Silberstein SD. Fatigue in chronic migraine patients. Cephalalgia 2002;22(9):720-4.

Fox A. Migraine chronobiology. Headache 1998;38:431-1.

Dement W, Kleitman N. The relation of eye movements during sleep to dream activity: An objective method for the study of dreaming. J Exp Psychol 1957;53(5):339-46.

Egilius L. Fatigue and sleep in chronic headache sufferers: An age-and sex-controlled questionnaire study. Headache 1997;37(9):549-52.

Levitan H. Dreams which culminate in migraine headaches. Psychother Psychosom 1984;41(4):161-6.

Stovner LJ, Hagen K. Prevalence, burden, and cost of headache disorders. Curr Opin Neurol 2006;19(3):281-5. Calhoun AH, Ford S, Finkel AG, Kahn KA, Mann JD. The prevalence and spectrum of sleep problems in women with transformed migraine. Headache 2006;46(4):604-10.

How to Cite
1.
Sadeghniiat K, Rajabzadeh A, Ghajarzadeh M, Ghafarpour M. Sleep Quality and Depression among Patients with Migraine. Acta Med Iran. 51(11):784-788.
QRcode
Section
Articles