Relation between Asthma and Body Mass Index in 6-15 Years Old Children
,
Abstract
Childhood asthma and obesity are significant public health problems. Most prospective studies suggest that obesity increases the risk of asthma. But, some authors did not found this association. In this study the association between asthma and body mass index (BMI) was investigated. This case-control study was conducted on 200 asthmatic children aged 6-15 years and 200 children without asthma. The criteria for asthma diagnosis and its classification were on the basis of National Asthma Education and Prevention Program (NAEPP). BMI of patients and controls were also measured and BMI grater than 85% and 95% were defined as overweight and obese respectively. The data was analyzed by SPSS software. The BMI among the asthmatic children (17.9 kg/m2) was higher than the BMI among the non-asthmatics (16.5 kg/m2), P=0.0001. This relationship was significant in both males and females. 18% of asthmatic children were classified as overweight and 13.5% of them were obese versus 7.5% and 6% respectively in non asthmatics (P=0.0001). However, there was no significant relationship between severity, duration of asthma, kind of medication and BMI in children with asthma (P>0.05). Result of this study showed that there is an association between asthma symptoms and obesity in children. Therefore, any attempts for weight control in asthmatic children might be beneficial.
Van Cleave J, Gortmaker SL, Perrin JM. Dynamics of obesity and chronic health conditions among children and youth. JAMA 2010;303(7):623-30.
Kelishadi R. Childhood Overweight, Obesity, and the Metabolic Syndrome in Developing Countries. Epidemiol Rev 2007;29(1):62-76.
Bahreinian S, Ball G, Becker A, Kozyrskyj A. Comorbidity with depression and overweight in children with asthma. Allergy Asthma and Clinical Immunology 2010;6(suppl2):P10.www.aacijournal.com/content/6/S2/P10
Moreau D, Kalaboka S, Choquet M, Annesi-Maesano I. Asthma, obesity, and eating behaviors according to the diagnostic and statistical manual of mental disorders IV in a large population-based sample of adolescents. Am J Clin Nutr 2009;89(5):1292-8.
Shore SA. Obesity and asthma: possible mechanisms. J Allergy Clin Immunol 2008;121(5):1087-93.
Matos SM, Jesus SR, Saldiva SR, Prado MS, D'Innocenzo S, Assis AM, Rodrigues LC, Alcantara-Neves NM, Cruz ÁA, Simões Sde M, Barreto ML; SCAALA (Social Change, Asthma and Allergy in Latin America) Study Group. Overweight, asthma symptoms, atopy and pulmonary function in children of 4-12 years of age: findings from the SCAALA cohort in Salvador, Bahia, Brazil. Public Health Nutr 2011;14(7):1270-8.
Sutherland TJ, Cowan JO, Young S, Goulding A, Grant AM, Williamson A, Brassett K, Herbison GP, Taylor DR. The association between obesity and asthma: interactions between systemic and airway inflammation. Am J Respir Crit Care Med 2008;178(5):469-75. .
Von Mutius E, Schwartz J, Neas LM, Dockery D, Weiss ST. Relation of body mass index to asthma and atopy in children: the National Health and Nutrition Examination Study III. Thorax 2001;56(,11):835-8.
Beuther DA, Sutherland ER. Overweight, obesity, and incident asthma: a meta-analysis of prospective epidemiologic studies. Am J Respir Crit Care Med 2007;175(5):661-6.
Cassol VE, Rizzato TM, Teche SP, Basso D, Centenaro DF, Maldonado M, Moraes EZ, Hirakata VN, Solé D, Menna-Barreto SS. Obesity and its relationship with asthma prevalence and severity in adolescents from southern Brazil. J Asthma 2006;43(1):57-60.
Henkin S, Brugge D, Bermudez OI, Gao X. A case-control study of body mass index and asthma in Asian children. Ann Allergy Asthma Immunol 2008;100(5):447-51.
Leung TF, Kong AP, Chan IH, Choi KC, Ho C, S., Chan MH, So WY, Lam CW, Wong GW, Chan JC. Association between obesity and atopy in Chinese schoolchildren. Int Arch Allergy Immunol 2009;149(2):133-40.
Deesomchok A, Fisher T, Webb KA, Ora J, Lam YM, Lougheed MD, O'Donnell DE. Effects of obesity on= perceptual and mechanical responses to bronchoconstriction in asthma. Am J Respir Crit Care Med 2010;181(2):125-33.
To T, Vydykhan TN, Dell S, Tassoudji M, Harris JK. Is obesity associated with asthma in young children? J pediatr 2004;144(2):162-8.
Vàzquez-Nava F, Morales Romero J, Crodova Fernandez JA, Saldívar-González AH, Vázquez-Rodriguez CF, Barrientos Gomez Mdel C, Lin-Ochoa D, Vázquez Rodríguez EM. Association between obesity and asthma in preschool Mexican children. Scientific World Journal 2010;7(10):1339-46.
Epstein LH, Wu YW, Paluch RA, Cerny FJ, Dorn JP. Asthma and maternal body mass index are related to pediatric body mass index and obesity: results from the Third National Health and Nutrition Examination Survey. Obes Res 2000;8(8):575-81.
Nathell L, Jensen I, LarssonL K. High prevalence of obesity in asthmatic patients on sick leave. Respir Med 2002;96(8):642-50.
NAEPP. (National Asthma Education and Prevention Program) Expert panel reports3: Guidelines for the diagnosis and management of asthma.: J Allergy Clin Immunol 2007;120(Suppl):S94–S138.
Kuczmarski RJ, Ogden CL, Grummer-Strawn LM, Flegal KM, Guo SS, Wei R, Mei Z, Curtin LR, Roche AF, Johnson CL. CDC growth charts: United States. Adv Data 2000;314:1-24.
Tai A, Volkmer R, Burton A. Association between asthma symptoms and obesity in preschool (4-5 year old) children. J Asthma 2009;46(4):362-5.
Bibi H, Shoseyov D, Feigenbaum D, Genis M, Friger M, Peled R, Sharff S. The relationship between asthma and obesity in children: is it real or a case of over diagnosis? J Asthma 2004;41(4):403-10.
Musaad SM, Patterson T, Ericksen M, Lindsey M, Dietrich K, Succop P, Khurana Hershey GK. Comparison of anthropometric measures of obesity in childhood allergic asthma: central obesity is most relevant. J Allergy Clin Immunol 2009;123(6):1321-7.
Amra B, Rahmani A, Salimi S, Mohammadzadeh Z, Golshan M. Association between Asthma and Body Mass Index in Children. Iran J Allergy Asthma Immunol 2005;4(1):33-7.
Lugogo NL, Hollingsworth JW, Howell DL, Que LG, Francisco D, Church TD, Potts-Kant EN, Ingram JL, Wang Y, Jung SH, Kraft M. Alveolar Macrophages from Overweight/Obese Asthmatic Subjects Demonstrate a Proinflammatory Phenotype. Am J Respir Crit Care Med 2012;186:11-6.
Poulain M, Doucet M, Major GC, Drapeau V, Sériès F, Boulet LP, Tremblay A, Maltais F. The effectof obesity on chronic respiratory diseases: pathophysiology and therapeutic strategies. CMAJ 2006;174(9):1293-9.
Castro-Rodríguez JA, Holberg CJ, Morgan WJ, Wright AL, Martinez FD. Increased incidence of asthmalike symptoms in girls who become overweight or obese during the school years. Am J Respir Crit Care Med 2001;163(6):1344-9.
Hancox R, Milne BJ, Poulton R, Taylor DR, Greene JM, McLachlan CR, Cowan JO, Flannery EM, Herbison GP,Sears MR. Sex differences in the relation between body mass index and asthma and atopy in a birth cohort. Am J Respir Crit Care Med 2005;171(5):440-5. 28. Weiss ST, Shore S. Obesity and asthma: directions for research. Am J Respir Crit Care Med 2004;169(8):963-8.
Oddy WH, Sherriff JL, de Klerk NH, Kendall GE, Sly PD, Beilin LJ, Blake KB, Landau LI, Stanley FJ. The relation of breastfeeding and body mass index to asthma and atopy in children: a prospective cohort study to age 6 years. Am J Public Health 2004;94(9):1531-7.
Yoo S, Kim HB, Lee SY, Kim BS, Kim JH, Yu JH, Kim BJ, Hong SJ. Association between obesity and the prevalence of allergic diseases, atopy, and bronchial hyperresponsiveness in Korean adolescents. Int Arch Allergy Immunol 2011;154(1):42-48.
Hom J, Morley EJ, Sasso P, Sinert R. Body mass index and pediatric asthma outcomes. Pediatr Emerg Care 2009;25(9):569-71.
Lang JE, Hossain J, Smith K, Lima JJ. Asthma severity, exacerbation risk, and controller treatment burden in underweight and obese children. J Asthma 2012;49(5):456-63.
Akerman MJ, Calacanis CM, Madsen MK. Relationship Between Asthma Severity and Obesity. Journal of Asthma 2004;41(5):521-6
Anderson WJ, Lipworth BJ. Does body mass index influence responsiveness to inhaled corticosteroids in persistent asthma? Ann Allergy Asthma Immunol 2012;108(4):237-42.
Calvert J, Burney P. Effect of body mass on exerciseinduced bronchospasm and atopy in African children. J Allergy Clin Immunol 2005;116:773-9.
Schachter LM, Peat JK, Salome CM. Asthma and atopy in overweight children. Thorax 2003;58(12):1031-5.
Tsai SY, Ward T, Lentz MJ, Kieckhefer GM. Daytime Physical Activity Levels in School-Age Children With and Without Asthma. Nurs Res 2012;61(4):252-9.
| Files | ||
| Issue | Vol 51, No 9 (2013) | |
| Section | Articles | |
| Keywords | ||
| Asthma BMI Obesity Overweight | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
