Idiopathic Great Saphenous Phlebosclerosis


Arterial sclerosis has been extensively described but reports on venous sclerosis are very sparse. Phlebosclerosis refers to the thickening and hardening of the venous wall. Despite its morphological similarities with arteriosclerosis and potential morbid consequences, phlebosclerosis has gained only little attention. We report a 72 year old male with paralysis and atrophy of the right leg due to childhood poliomyelitis who was referred for coronary artery bypass surgery. The great saphenous vein, harvested from the left leg, showed a hardened cord-like obliterated vein. Surprisingly, harvested veins from the atrophic limb were normal and successfully used for grafting.

Marti MC, Bouchardy B, Cox JN. Aortocoronary bypass with autogenous saphenous vein grafts: histopathological aspects. Virchows Arch Abt A Path Anat 1971;352:255-66.

Yamada T, Itoh T, Nakano S, Tokunaga D, et al. Timedependent thickening of the intima in aortocoronary saphenous vein grafts: clinicopathological analysis of 24 patients. Heart Vessels 1995;10:41-5.

Charan. Diffuse phlebosclerosis with calcification. Br Med J 1953;1(4801):80-1.

Leu HJ, Vogt M, Pfrunder H, Odermatt BF. Phlebosclerosis: disorder or disease? Vasa 1991;20(3):230-6.

Kane-ToddHall SM, Taggart SP, Clements-Jewery H, Roskell DE. Pre-existing vascular disease in the radial artery and other coronary artery bypass conduits. Eur J Med Res 1999;4(1):11-4.

Tzogias L, Labropoulos N, Amaral SI, Antoniou GA, Giannoukas AD. Distribution and clinical impact of phlebosclerosis. Int Angiol 2011;30(3):212-20.

IssueVol 51, No 6 (2013) QRcode
Coronary bypass Phlebosclerosis Saphenous vein

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How to Cite
Jodati A, Kazemi B, Safaei N, Shokoohi B. Idiopathic Great Saphenous Phlebosclerosis. Acta Med Iran. 1;51(6):425-426.