Quality of Life in Patients with Bipolar I Disorder: Is It Related to Disorder Outcome?

  • Amir Shabani Department of Psychiatry, Mental Health Research Center, Iran University of Medical Sciences, Tehran, Iran.
  • Masoud Ahmadzad-Asl Mail Department of Psychiatry, Tehran Psychiatry Institute, Iran University of Medical Sciences, Tehran, Iran.
  • Kambiz Zangeneh Department of Psychiatry, Mental Health Research Center, Iran University of Medical Sciences, Tehran, Iran.
  • Samaneh Teimurinejad Department of Psychiatry, Tehran Psychiatry Institute, Iran University of Medical Sciences, Tehran, Iran.
  • Sadaf Kokar Department of Psychiatry, Tehran Psychiatry Institute, Iran University of Medical Sciences, Tehran, Iran.
  • Mojgan Taban Bachelors in Psychology, Mental Health Research Center, Iran University of Medical Sciences, Tehran, Iran.
  • Behnam Shariati Department of Psychiatry, Tehran Psychiatry Institute, Iran University of Medical Sciences, Tehran, Iran.
  • Zohreh Mousavi Behbahani Department of Psychiatry, Tehran Psychiatry Institute, Iran University of Medical Sciences, Tehran, Iran.
  • Mohammadreza Ghasemzadeh Department of Psychiatry, Tehran Psychiatry Institute, Iran University of Medical Sciences, Tehran, Iran.
  • Sahar Hasani Department of Psychiatry, Tehran Psychiatry Institute, Iran University of Medical Sciences, Tehran, Iran.
  • Shabnam Nohesara Department of Psychiatry, Tehran Psychiatry Institute, Iran University of Medical Sciences, Tehran, Iran.
  • Somayyeh Tat Department of Psychiatry, Tehran Psychiatry Institute, Iran University of Medical Sciences, Tehran, Iran.
  • Shahabali Shirkhoda Department of Psychiatry, Tehran Psychiatry Institute, Iran University of Medical Sciences, Tehran, Iran.
  • Zahra Ghorbani Department of Psychiatry, Tehran Psychiatry Institute, Iran University of Medical Sciences, Tehran, Iran.
  • Seyed Vahid Shariat Department of Psychiatry, Tehran Psychiatry Institute, Iran University of Medical Sciences, Tehran, Iran.
Keywords:
BDPF, Bipolar I Disorder, Quality of life, Recurrence

Abstract

Bipolar I disorder (BID) and its treatments have shown to be associated with deep impacts on patients' subjective feelings and quality of life (QOL). There are also some comments about impact of these feelings on course and outcome of patients with BID. This study was aimed to evaluate quality of life in patients with BID and to assess its relationship with course of disorder. Fifty patients with BID were recruited based on the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) from May 2008 and followed for 12 months. Quality of life and mood disorder recurrence were assessed through World Health Organization Quality of Life and SCID-I tools respectively at baseline and after 6 and 12 months. Repeated measures analysis and logistic regression were used to analyze the independent effect of QOL and demographic factors on BID recurrence. Fifty patients (66% male; 48% never married; 48% in primary school level) with mean ± SE age and age of BID onset 33.8±1.5 and 26.6±1.1 years were studied. They had 3.4±0.6 episodes already. Twenty eight percent suffered from recurrences during the follow-up. The QOL scores at baseline, after 6 and 12 months were 70±1.8, 69.6±1.1 and 73±1.3 respectively. There were no significant change in QOL and its sub-domains during the follow-up (P=0.37). QOL showed no independent relationship with BID recurrences (P>0.1). No change in the QOL during the follow-up could denote lack of effectiveness of routine interventions on this factor. Also, short-term follow-up might be concerned as the possible reason. Of prime importance is to consider quality of life independently in treating patients with bipolar disorder.

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How to Cite
1.
Shabani A, Ahmadzad-Asl M, Zangeneh K, Teimurinejad S, Kokar S, Taban M, Shariati B, Mousavi Behbahani Z, Ghasemzadeh M, Hasani S, Nohesara S, Tat S, Shirkhoda S, Ghorbani Z, Shariat SV. Quality of Life in Patients with Bipolar I Disorder: Is It Related to Disorder Outcome?. Acta Med Iran. 51(6):386-393.
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