Cutaneous Leishmaniasis with Unusual Clinical and Histological Presentation: Report of Four Cases
Abstract
Old world cutaneous leishmaniasis (OWCL) usually causes a single, self-healing and uncomplicated lesion mainly on the exposed area of body. This report presents four cases of OWCL from Iran that misdiagnosed with sarcoidosis, lymphoma, and acne agminata. Two out of four patients showed a history of purplish red plaques for at least 5 years who misdiagnosed as sarcoidosis because of histological and clinical characteristics. The other one presented with flesh-colored nodules disseminated all over his skin that was misdiagnosed as lymphoma for ten years. The last patient was misdiagnosed as acne agminata due to tuberculoid reactions in examination of the lesion biopsy. All the patients responded to the treatment with meglumine antimonate.
Control of the leishmaniases. Report of a WHO Expert Committee. World Health Organ Tech Rep Ser 1990;793:1-158.
Mohebali M, Motazedian MH, Parsa F, Hajjaran H. Identification of Leishmania species from different parts of Iran using a random amplified polymorphic DNA in human, animal reservoirs and vectors. The Medical Journal of the Islamic Republic of Iran 2002;15(4):243-6.
Rassi Y, Abai MR, Javadian E, Rafizadeh S, Imamian H, Mohebali M, et al. Molecular data on vectors and reservoir hosts of zoonotic cutaneous leishmaniasis in central Iran. Bull Soc Pathol Exot 2008;101(5):425-8.
Akilov OE, Khachemoune A, Hasan T. Clinical manifestations and classification of Old World cutaneous leishmaniasis. Int J Dermatol 2007;46(2):132-42.
Venencie PY, Bouree P, Hiesse C, Vieillefond A, Lantz O, Doukan S, et al. [Disseminated cutaneous leishmaniasis in a case of an immunodepressed woman]. Ann Dermatol Venereol 1993;120(6-7):461-3.
Castellino G, Govoni M, Lo Monaco A, Montecucco C, Colombo F, Trotta F. Visceral leishmaniasis complicating a connective tissue disease: three case reports from Italy. Lupus 2004;13(3):201-3.
Vardy DA, Cohen A, Kachko L, Zvulunov A, Frankenburg S. Relapse of cutaneous leishmaniasis in a patient with an infected subcutaneous rheumatoid nodule. Br J Dermatol 1999;141(5):914-7.
Jafari S, Hajiabdolbaghi M, Mohebali M, Hajjaran H, Hashemian H. Disseminated leishmaniasis caused by Leishmania tropica in HIV-positive patients in the Islamic Republic of Iran. East Mediterr Health J 2010;16(3):340-3.
Saha M, Shipley D, McBride S, Kennedy C, Vega-Lopez F. Atypical cutaneous leishmaniasis in two patients receiving low-dose methotrexate. Br J Dermatol 2006;155(4):830-3.
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Issue | Vol 51, No 4 (2013) | |
Section | Original Article(s) | |
Keywords | ||
Acne agminata Cutaneous leishmaniasis Leishmania Lymphoma Sarcoidosis |
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