Venous Thromboembolism in Medical Critically Ill Patients: Prevalence and Incidence
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Parisa Adimi Naghan
,
Majid Malekmohammad
,
Hamidreza Jamaati
,
Babak Sharifkashani
,
Arvin Najafi
,
Seyed Mohammadreza Hashemian
Abstract
The objective of this study was to determine the prevalence and incidence of venous thromboembolism among critically ill medical surgical patients. In this cross sectional and retrospective study, we observed 243 patients who were first admitted at the intensive care unit. Patients who were diagnosed with deep venous thrombosis or embolism either by clinical or paraclinical methods were enrolled. Among 243 patients of ICU ward 12 cases of them were confirmed to have thromboembolism (prevalence of 9.4%).But the incidence of venous thromboembolism after 48 hour of ICU admission was 5.2%(6 cases). Among 6 VTE cases 3 of them didn't receive any anticoagulant prophylaxis, 2 patients received LDUH 5000 unit twice a day and one patient received LMWH 60 mg daily but all developed VTE although receiving prophylaxis. We found that the prevalence of proximal lower limb DVT among medical-surgical critically ill patients remaining in the ICU for ≥3 days is about 9.4% and the incidence of that is about 5.2%. Further studies should be performed in order to assess the benefits and risks of venous thromboprophylaxis in Iranian patients.
Muscedere JG, Heyland DK, COOK D. Venous thromboembolism in critical illness in a community intensive care unit. J crit care 2007;22(4):285-9.
Attia J, Ray JG, Cook DJ, Douketis J, Ginsberg JS, Geerts WH. Deep vein thrombosis and its prevention in critically ill patients. Arch Intern Med 2001;161(10):1268–79.
Marik PE, Andrews L, Maini B. The incidence of deep venous thrombosis in ICU patients. Chest 1997;111(3):661–4.
Hirsch DR, Ingenito EP, Goldhaber SZ. Prevalence of deep venous thrombosis among patients in medical intensive care. JAMA 1995;274(4):335–7.
Harris LM, Curl GR, Booth FV, Hassett JM Jr, Leney G, Ricotta JJ. Screening for asymptomatic deep vein thrombosis in surgical intensive care patients. J Vasc Surg 1997;26(5):764–9.
McKelvie PA. Autopsy evidence of pulmonary thromboembolism. Med J Australia 1994;160(3):127–8.
Douketis JD, Foster GA, Crowther MA, Prins MH, Ginsberg JS. Clinical risk factors and timing of recurrent venous thromboembolism during the initial 3 months of anticoagulant therapy. Arch Intern Med 2000; 160(22):3431-6.
Ibrahim EH, Iregui M, Prentice D, Sherman G, Kollef MH, Shannon W. Deep vein thrombosis during prolonged mechanical ventilation despite prophylaxis. Crit Care Med2002; 30(4):771-4.
Patel R, Cook DJ, Meade MO, Griffith LE, Mehta G, Rocker GM, Marshall JC, Hodder R, Martin CM, Heyland DK, Peters S, Muscedere J, Soth M, Campbell N, Guyatt GH. Burden of Illness in venous ThromboEmbolism in Critical care (BITEC) Study Investigators; Canadian Critical Care Trials Group. Burden of illness in venousthromboembolism in critical care: a multicenter observational study. J crit care 2005;20(4):341-7.
Cook D, Attia J, Weaver B, McDonald E, Meade M, Crowther M. Venous Thromboembolic disease: an observational study in medical – Surgical intensive care unit patients. J crit care 2000;15(4):127-32.
Kearon C, Julian JA, Newman TE, Ginsberg JS. Noninvasive diagnosis of deep venous thrombosis. McMaster Diagnostic Imaging Practice Guidelines Initiative. Ann Intern Med 1998;128(8):663-77.
Schonhofer B, Kohler D. Prevalence of deep vein thrombosis of the leg in patients with acute exacerbation of chronic obstructive pulmonary disease. Respiration 1998;65(3):173-7.
Moser KM, LeMoine JR, Nachtwey FJ, Spragg RG. Deep venous thrombosis and pulmonary embolism: Frequency in a respiratory intensive care unit. JAMA 1981;246(13):1422-4.
Fraser JD, Anderson DR. Deep venous thrombosis: Recent advances and optimal investigation with ultrasound. Radiology 1999;211(1):9-24.
Burn PR, Blunt DM, Sansom HE, Phelan MS. The radiological investigation of suspected lower limb deep vein thrombosis. Clin Radiol 1997;52(8):625-8.
Cook D, McMullin J, Hodder R, Heule M, Pinilla J, Dodek P, Stewart T. Canadian ICU Directors Group. Prevention and diagnosis of venous thromboembolism in critically ill patients: A Canadian survey. Crit Care 2001; 5(6):336-42.
| Files | ||
| Issue | Vol 51, No 3 (2013) | |
| Section | Original Article(s) | |
| Keywords | ||
| Critically illness Prevalence Thromboembolism Venous thrombosis | ||
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