Articles

Larvicidal Activities of Some Iranian Native Plants against the Main Malaria Vector, Anopheles stephensi

Abstract

Malaria is considered a major health problem in Iran. There are different methods for vector control. In this study we tested the larvicidal effects of some Iranian plants. The methanolic extracts of 11 plants were prepared with percolation method. The larvicidal activities of them against malaria vector, Anopheles stephensi were studied using World Health Organization standard method. All LC50 values of methanolic extracts of plants that we screened were lower than 300 ppm. The methanolic extract of aerial parts of Lawsonia inermis and Stachys byzantina showed high larvicidal activity with LC50 values 69.40 ppm and 103.28 ppm respectively. The results obtained from this study suggest that the methanolic extracts of these plants have larvicidal effects against Anopheles stephensi larvae and could be useful in the search for new natural larvicidal compounds.

Becker N, Petrie D, gomba M, Boase C. Mosquitoes and their control. 2 ed. New York: Kluwer Academic-PlenumPublishers; 2010.

Mehravaran A, Vatandoost H, Oshaghi MA, Abai MR, Edalat H, Javadian E, Mashayekhi M, Piazak N, Hanafi- Bojd AA. Ecology of Anopheles stephensi in a malariousarea, southeast of Iran. Acta Med Iran 2012;50(1):61-5.

Naddaf SR, Oshaghi MA, Vatandoost H, Assmar M. Molecular characterization of Anopheles fluviatilis species complex in the Islamic Republic of Iran. East Mediterr Health J 2003;9(3):257-65.

Vatandoost H, Vaziri VM. Larvicidal activity of a neem tree extract (Neemarin) against mosquito larvae in the Islamic Republic of Iran. East Mediterr Health J 2004;10(4-5):573-81.

Vatandoost H, Oshaghi MA, Abaie MR, Shahi M, Yaghoobi F, Baghaii M, Hanafi-Bojd AA, Zamani G,Townson H. Bionomics of Anopheles stephensi Liston in the malarious area of Hormozgan province, southern Iran, 2002. Acta Trop 2006;97(2):196-203.

Hanafi-Bojd AA, Vatandoost H, Jafari R. Susceptibility status of Anopheles dthali and An. fluviatilis to commonly used larvicides in an endemic focus of malaria, southern Iran. J Vector Borne Dis 2006;43(1):34-8.

Vatandoost H, Zahirnia AH. Responsiveness of Anopheles maculipennis to different imagicides during resurgent malaria. Asian Pacific J Trop Med 2010;3(5):360-3.

Vatandoost H, Hanafi-Bojd AA. Laboratory evaluation of 3 repellents against Anopheles stephensi in the Islamic Republic of Iran. East Mediterr Health J 2008;14(2):260-7.

Vatandoost H, Khazani A, Rafinejad J, Khoobdel M, Kebriai-Zadeh A, Abai MR, Hanafi-Bojd AA, Akhavan AA, Abtahi M, Rafi F. Comparative efficacy of Neem and dimethyl phthalate (DMP) against malaria vector, Anopheles stephensi (Diptera: Culicidae). Asian Pacific J Trop Med 2008;1(3):1-6.

Vatandoost H, Emami SN, Oshaghi MA, Abai MR, Raeisi A, Piazzak N, Mahmoodi M, Akbarzadeh K, Sartipi M. Ecology of malaria vector Anopheles culicifacies in a malarious area of Sistan va Baluchestan province, southeast Islamic Republic of Iran. East Mediterr Health J 2011;17(5):439-50.

Abai MR, Mehravaran A, Vatandoost H, Oshaghi MA, Javadian E, Mashayekhi M, Mosleminia A, Piyazak N, Edallat H, Mohtarami F, Jabbari H, Rafi F. Comparative performance of imagicides on Anopheles stephensi, main malaria vector in a malarious area, southern Iran. J Vector Borne Dis 2008;45(4):307-12.

Sedaghat MM, Linton YM, Nicolescu G, Smith L, Koliopoulos G, Zounos AK, Oshaghi MA, Vatandoost H, Harbach RE. Morphological and molecular characterization of Anopheles (Anopheles) sacharovi Favre, a primary vector of malaria in the Middle East. Syst Entomol 2003;28(2):241-56.

Sedaghat MM, Linton YM, Oshaghi MA, Vatandoost H, Harbach RE. The Anopheles maculipennis complex (Diptera: Culicidae) in Iran: molecular characterization and recognition of a new species. Bull Entomol Res 2003;93(6):527-35.

Oshaghi MA, Sedaghat MM, Vatandoost H. Molecular characterization of the Anopheles maculipennis complex in the Islamic Republic of Iran. East Mediterr Health J 2003;9(4):659-66.

Doosti S, Azari-Hamidian S, Vatandoost H, Oshaghi MA, Hosseini M. Taxonomic differentiation of Anopheles sacharovi and An.maculipennis S.l. Acta Med Iran 2006;44(1):41-3.

Truman LC, Bennett GW, Butts WL. Scientific Guide to Pest Control Operations. Taylor & Francis.

Chaithong U, Choochote W, Kamsuk K, Jitpakdi A, Tippawangkosol P, Chaiyasit D, Champakaew D, Tuetun B, Pitasawat B. Larvicidal effect of pepper plants on Aedes aegypti (L.)(Diptera: Culicidae). J Vector Ecol 2006;31(1):138-44.

Mittal P, Subbarao S. Prospects of using herbal products in mosquito control. ICMR Bull 2003;33(1):1-10.

Sukumar K, Perich MJ, Boobar LR. Botanical derivatives in mosquito control: a review. J Am Mosq Control Assoc 1991;7(2):210-37.

Gupta A. Quality standards of Indian medicinal plants. Indian council of medicinal research. ICMR 2003;1:123-9.

Sastri BN. The wealth of India. Raw materials 1962;4:275-7.

Chetty KM. Flowering Plants of Chittoor. Edn 2008;1:132.

Chopra RN, Nayar SL, Chopra IC. Glossary of Indian medicinal plants. New Delhi : C SIR 1956.

Reddy KR. Folk medicine from Chittoor District, Andhra Pradesh, India, used in the treatment of jaundice. Pharmaceutical Biology 1988;26(3):137-40.

Khanavi M, Farahanikia B, Rafiee F, Safaripour E, Dalili D, Ajani Y, et al. Reversal of resistance in MRSA strainsbyThymus kotschyanus essential oil [Thesis in Pharm 4889]. Tehran, Iran: Department of Faculty of Pharmacy, Tehran University of Medical Sciences; 2009.

Fathi M. Comparison of the volatile compositions and calibrative determination of effective components of Thymus kotschyanus [Thesis in Pharm 4758]. Tehran, Iran: Department of Pharmacognosy and Department of Drug and Food Control, Faculty of Pharmacy, Tehran University of Medical Sciences; 2008.

Talei GHR, Meshkat Alsadat MH, Mousavi Z. Antibacterial activity and chemical composition of essential oils from four medicinal plants of Lorestan, Iran. Journal of Medicinal Plants 2007;6(1):45-52.

Haji MH, Khanavi M, Zahedi H, Abedi Z, Kalantari KN, Adib N, Pirali Hamedani M. Fingerprint study of Thymus spp. by TLC. J Med Plants 2009;8(31):19-24.

Mohammed MJ, Al-Bayati FA. Isolation and identification of antibacterial compounds from Thymus kotschyanus aerial parts and Dianthus caryophyllus flower buds. Phytomedicine 2009;16(6):632-7.

Zargari A. Medicinal plants, vol. 3. Tehran University Publications, Tehran 1996;513:38.

Ghahreman A. Flora of Iran. Published by Research Institute of Forests and Rangelands (RIFR), Tehran 1997;16(1944).

Samsam Shariat H. Collection of medicinal herbs. Char Bagh Publication, Tehran 2007;11-2.

Morteza-Semnani K, Mahmoudi M, Riahi G. Effects of Essential Oils and Extracts from Certain Thymus. Species on Swimming Performance in Mice. Pharm Biol 2007;45(6):464-7.

Naghibi F, Mosaddegh M, Mohammadi Motamed S, Ghorbani A. Labiatae family in folk medicine in Iran: from ethnobotany to pharmacology. Iranian Journal of Pharmaceutical Research 2009;4(2):63-79.

Skaltsa H, Bermejo P, Lazari D, Silvan AM, Skaltsounis AL, Sanz A, Abad MJ. Inhibition of prostaglandin E2 and leukotriene C4 in mouse peritoneal macrophages and thromboxane B2 production in human platelets by flavonoids from Stachys chrysantha and Stachys candida. Biol Pharm Bull 2000;23(1):47-53.

Mozaffarian V. A Dictionary of Iranian Plant Names. Tehran: Farhang Mo'aser; 1996.

Khanavi M, Sharifzadeh M, Hadjiakhoondi A, Shafiee A. Phytochemical investigation and anti-inflammatory activity of aerial parts of Stachys byzanthina C. Koch. J Ethnopharmacol 2005;97(3):463-8.

Skaltsa HD, Lazari DM, Chinou IB, Loukis AE. Composition and antibacterial activity of the essential oils of Stachys candida and S. chrysantha from Southern Greece. Planta medica 1999;65(3):255-6.

Kukic J, Dobric S, Petrovic S. Influence of Some Stachys.Taxa on Carrageenan-Induced Paw Edema in Rats. Pharm Biol 2007;45(7):560-3.

Sharifzadeh M, Sharifzadeh K, Khanavi M, HadjiakhoondiA, Shafiee A. Anti-inflammatory activity of aerial parts of Stachys setifera and Stachys persica. Int J Pharmacol 2005;1:132-7.

Rabbani M, Sajjadi SE, Zarei HR. Anxiolytic effects ofStachys lavandulifolia Vahl on the elevated plus-maze model of anxiety in mice. J Ethnopharmacol 2003;89(2-3):271-6.

Sonboli A, Salehi P, Nejad Ebrahimi S. Essential oil composition and antibacterial activity of the leaves of Stachys schtschegleevii from Iran. Chemistry of natural compounds 2005;41(2):171-4.

Digrak M, Alma MH, Ilim A. Antibacterial and antifungal activities of Turkish medicinal plants. Pharmaceutical Biology 2001;39(5):346-50.

Hayashi K, Nagamatsu T, Ito M, Hattori T, Suzuki Y. Acteoside, a component of Stachys sieboldii MIQ, may be a promising antinephritic agent (2): Effect of acteoside on leukocyte accumulation in the glomeruli of nephritic rats. Jpn J Pharmacol 1994;66(1):47.

Amirghofran Z, Bahmani M, Azadmehr A, Javidnia K. Anticancer effects of various Iranian native medicinal plants on human tumor cell lines. Neoplasma 2006;53(5):428-33.

Amirghofran Z, Bahmani M, Azadmehr A, Javidnia K. Immunomodulatory and apoptotic effects of Stachys obtusicrena on proliferative lymphocytes. Med Sci Monit 2007;13(6):145-50.

Stamatis G, Kyriazopoulos P, Golegou S, Basayiannis A, Skaltsas S, Skaltsa H. In vitro anti-Helicobacter pylori activity of Greek herbal medicines. J Ethnopharmacol 2003;88(2-3):175-9.

Erdemoglu N, Turan NN, Cakc I, Sener B, Aydn A. Antioxidant activities of some Lamiaceae plant extracts. Phytother Res 2006;20(1):9-13.

cacute J, cacute S, cacute M. Antioxidant activity of four endemic Stachys taxa. Biol Pharm Bull 2006;29(4):725-9.

Matkowski A, Piotrowska M. Antioxidant and free radical scavenging activities of some medicinal plants from the Lamiaceae. Fitoterapia 2006;77(5):346-53.

Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. Montvale, NJ: Medical Economics Company. Inc; 1998.

Mhaskar KS, Blatter E, Caius JF, Ram VA. Kirtikar and Basu's Illustrated Indian medicinal plants: their usage in Ayurveda and Unani medicines. Sri Satguru Publications; 2000.

Bhakuni DS, Dhar ML, Dhar MM, Dhawan BN, MehrotraBN. Screening of Indian plants for biological activity: Part II. Indian J Exp Biol 1969;7:250-62.

Sachin BS, Koul M, Zutshi A, Singh SK, Tikoo AK, TikooMK, Saxena AK, Sharma SC, Johri RK. Simultaneous high-performance liquid chromatographic determination of Cedrus deodara active constituents and their pharmacokinetic profile in mice. J Chromatogr B 2008;862(1-2):237-41.

WHO. Entomology and Vector Control. Guide for Participants. WHO, Geneva; 2011.

Finney DJ. Probit Analysis. 3. 1971. London, UK, Cambridge University Press. Abbott WS. A method of computing the effectiveness of an insecticide. J Am Mosq Control Assoc 1925;3(2):302-3.

Hadjiakhoondi A, Aghel N, Zamanizadeh N, Vatandoost H. Chemical and Biological study of Mentha spicata L. essential oil from Iran. Daru 2000;8(1-2):19-21.

Hadjiakhoondi A, Sadeghipour-Roodsari HR, Vatandoost H, Khanavi M, Abai MR, Vosoughi M, Kazemi M. Fatty acid composition and toxicity of Melia azedarach L. fruits against malaria vector Anopheles stephensi. Iran J Pharm Sci 2006;2(2):97-102.

Hadjiakhoondi A, Vatandoost H, Jamshidi A, BagherjAmiri E. Chemical constituents and efficacy of Cymbopogon olivieri (Boiss) bar essential oil againstmalaria vector, Anopheles stephensi. Daru 2003;11(3):125-8.

Hadjiakhoondi A, Vatandoost H, Khanavi M, Abai MR. Biochemical investigation of different extracts and larvicidal activity of Tagetes minuta L on Anopheles stephensi larvae. Iran J Pharm Sci 2005;1:81-4.

Hadjiakhoondi A, Vatandoost H, Abousaber M, Khanavi M, Abdi L. Chemical composition of the essential oil of Tagetes minuta L. and its effects on Anopheles stephensi larvae in Iran. J Med Plants 2000;7(2):33-9.

Chaudhary G, Goyal S, Poonia P. Lawsonia inermis Linnaeus: A Phytopharmacological Review. Int J Pharm Sci & Drug Res 2010;2(2):91-8.

Saeedi M, Morteza-Semnani K, Mahdavi MR, Rahimi F. Antimicrobial studies on extracts of four species of Stachys. Indian J Pharm Sci 2008;70(3):403.

Sedaghat MM, Dehkordi AS, Khanavi M, Abai MR, Hadjiakhoondi A, Mohtarami F, Vatandoost H. Phytochemistry and larvicidal activity of Eucalyptus camaldulensis against malaria vector, Anopheles stephensi. Asian Pac J Trop Med 2010;3(11):841-5.

Sedaghat MM, Dehkordi AS, Khanavi M, Abai MR, Mohtarami F, Vatandoost H. Chemical composition and larvicidal activity of essential oil of Cupressus arizonica E.L. Greene against malaria vector Anopheles stephensi Liston (Diptera: Culicidae). Pharmacognosy Res 2011;3(2):135-9.

Sedaghat MM, Dehkordi AS, Abaie MR, Khanavi M, Mohtarami F, Saim abadi Y, Rafi F, Vatandoost H.Larvicidal Activity of Essential Oils of Apiaceae Plants against Malaria Vector, Anopheles stephensi. Iran J Arthropod-Borne Dis 2011;5(2):51-9.

Senthil Nathan S. The use of Eucalyptus tereticornis Sm.(Myrtaceae) oil (leaf extract) as a natural larvicidal agent against the malaria vector Anopheles stephensi Liston (Diptera: Culicidae). Bioresource Technol 2007;98(9):1856-60.

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IssueVol 51, No 3 (2013) QRcode
SectionArticles
Keywords
Anopheles stephensi Iranian plant Larvicidal activities Methanolic extract

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1.
Khanavi M, Vatandoost H, Khosravi Dehaghi N, Sanei Dehkordi A, Sedaghat MM, Hadjiakhoondi A, Hadjiakhoondi F. Larvicidal Activities of Some Iranian Native Plants against the Main Malaria Vector, Anopheles stephensi. Acta Med Iran. 1;51(3):141-147.