Ischemic Stroke as a Rare Manifestation of Aluminum Phosphide Poisoning: a Case Report
Abstract
Aluminum phosphide (AlP) is a solid fumigant which is widely used for a suicide attempt in Iran. Although neurologic symptoms are commonly reported, cerebrovascular stenosis is rare in AlP poisoning. We described ischemic stroke as a delayed complication of AlP intoxication. A 30-year-old man was admitted because of sudden onset left side hemiplegia, 11 days after intentional ingestion of three rice tablets. Investigations revealed in situ thrombosis in right middle cerebral artery (MCA) while other causes of stroke in young adults were excluded. Ischemic stroke should be considered as a delayed complication of AlP intoxication even after the acute phase of intoxication.
Wahab A, Zaheer M, Wahab S, et al. Acute aluminium phosphide poisoning: an update. Hong Kong J Emerg Med 2008;15(3):152-5.
Moghadamnia AA. An update on toxicology of aluminum phosphide. Daru 2012;20(1):25.
Moazezi Z, Abedi SH. A successful management of aluminium phosphide intoxication. Caspian J Intern Med 2011;2(3):286-8.
Nath, NS, Bhattacharya I, Tuck AG, et al. Mechanisms of phosphine toxicity. J Toxicol 2011;2010:494168.
Brautbar N, Howard J. Phosphine toxicity: report of two cases and review of the literature. Toxicol Ind Health 2002;18(2):71-5.
Kurzbauer H, Kiesler A. Zawodowe zatrucie fosforowodorem [Occupational phosphine poisoning, in Polish]. Neurol Neurochir Pol 1987;21:415-7.
Dave HH, Dave TH, Rakholia VG, et al. Delayed haemorrhagic stroke following accidental aluminium phosphide ingestion. J Assoc Physicians India 1994;42(1):78-9.
Almasieh M, Lieven CJ, Levin LA, et al. A cell-permeable phosphineborane complex delays retinal ganglion cell death after axonal injury through activation of the prosurvival extracellular signal-regulated kinases 1/2 pathway. J Neurochem 2011;118(6):1075-86.
Anger F, Paysant F, Brousse F, et al. Fatal aluminumphosphide poisoning. J Anal Toxicol 2000;24(2):90-2.
Sinnha US, Kapoor AK, Singh AK, et al. Histopathological changes in cases of aluminium phosphide poinsoning. Indian J Pathol Microbiol 2005;48(2):177-80.
| Files | ||
| Issue | Vol 52, No 12 (2014) | |
| Section | Original Article(s) | |
| Keywords | ||
| Aluminium phosphide Poisoning Intoxication Stroke | ||
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