Cardio-Metabolic Risk Factors in Iranian Children: Where We are and the Others?
-
Setila Dalili
,
Seyed Mahmood Rezvani
,
Hossein Dalili
,
Zahra Mohtasham Amiri
,
Hamid Mohammadi
,
Abdolreza Medghalchi
,
Mohamad Hossein Novin
,
Hajar Gholamnezhad
Abstract
Rising obesity incidence and its complications have lead to change of our view about cardio-metabolic risk factors and need of reassessment of these complications in childhood age. The aim of current study was to evaluate prevalence of obesity and related cardio-metabolic risk factors of children. This was a cross-sectional study in a representative sample of 12 years old children in Rasht, the biggest city in north of Iran. Participants were interviewed and examined by a trained research team and demographic characteristics, detailed examination (height - weight - blood pressure) were recorded. Blood samples were drawn for biochemical testing including Fasting blood sugar, Triglyceride, Cholesterol, HDL & LDL. Data analysis was done using SPSS software. Total participants were 858 children and 550(64%) were male. Prevalence of underweight, normal weight, overweight, obese were 22.5%, 54.4%, 11.3%, 11.8%, respectively. The prevalence of cardio-metabolic risk factors included hypercholesterolemia (6.7%), hypertriglyceridemia (33.6%), high LDL (5.9%), low HDL (28 %), high systolic (7.6%) & diastolic blood pressure (10.6%) (> percentile) and abnormal carbohydrate metabolism (12%) revealed hypertriglyceridemia as the most common dyslipidemia. Correlation analysis didn't show significant correlation between BMI & FBS but LDL, Cholesterol and TG had week positive correlation with BMI (Pearson correlation: 0.161, 0.285, 0.222 respectively, p value <0.001). Obesity and dyslipidemia are common problems in this area and we should note to screen cardiometabolic risk factors in addition of obesity, especially in children with rapid weight gain. This study highly recommended more investigation to evaluate final effect of these factors in adulthood.
Ogden CL, Carroll MD, Curtin LR, et al. Prevalence of high body mass index in US children and adolescents, 2007-2008. JAMA 2010;303(3):242-9.
Ogden CL, Flegal KM, Carroll MD, et al. Prevalence and trends in overweight among US children and adolescents, 1999-2000. JAMA 2002;288(14):1728-32.
Sinha R, Fisch G, Teague B, et al. Prevalence of impaired glucose tolerance among children and adolescents with marked obesity. New Engl J Med 2002;346(11):802-10.
Perichart-Perera O, Balas-Nakash M, Schiffman-Selechnik E, et al. Obesity increases metabolic syndrome risk factors in school-aged children from an urban school in Mexico city. J Am Diet Assoc 2007;107(1):81-91.
Magnussen CG, Koskinen J, Chen W, et al. Pediatric metabolic syndrome predicts adulthood metabolic syndrome, subclinical atherosclerosis, and type 2 diabetes mellitus but is no better than body mass index alone: the Bogalusa Heart Study and the Cardiovascular Risk in Young Finns Study. Circulation 2010;122(16):1604-11.
Afzal MN, Naveed M. Childhood obesity and Pakistan. JCPSP 2004;14(3):189-92.
Lauer RM, Burns TL, Clarke WR, et al. Childhood predictors of future blood pressure. Hypertension 1991;18(3 Suppl):I74-81.
Stamler J. Epidemiologic findings on body mass and blood pressure in adults. Ann Epidemiol 1991;1(4):347-62.
Gillman MW, Ellison RC. Childhood prevention of essential hypertension. Pediatr Clin North Am 1993;40(1):179-94.
Figueroa-Colon R, Franklin FA, Lee JY, et al. Prevalence of obesity with increased blood pressure in elementary school-aged children. South Medical J 1997;90(8):806-13.
Chhatwal J, Verma M, Riar SK. Obesity among preadolescent and adolescents of a developing country (India). Asia Pac J Clinical Nutr 2004;13(3):231-5.
Health NI, editor. Lipid research clinics population studies data book. 1st ed. Washington: NIH Publication; 1980: p. 80-1527.
Seth A, Sharma R. Childhood Obesity. Indian J Pediatr 2013;80(4):309-17.
Raj M. Obesity and cardiovascular risk in children and adolescents. Indian J Endocrinol Metab 2012;16(1):13-9.
Li S, Chen W, Srinivasan SR, et al. Relation of childhood obesity/cardiometabolic phenotypes to adult cardiometabolic profile: the Bogalusa Heart Study. Am J Epidemiol 2012;176(Suppl 7):S142-9.
Behzadnia S, Vahidshahi K, Hamzeh Hosseini S, et al. Obesity and related factors in 7-12 year-old elementary school students during 2009-2010 in Sari, Iran. Med Glas 2012;9(1):86-90.
Fesharakinia A, Zarban A, Sharifzadeh GR. Lipid profiles and prevalence of dyslipidemia in schoolchildren in south Khorasan Province, eastern Iran. Arch Iran Med 2008;11(6):598-601.
Ghergerehchi R. Dyslipidemia in Iranian overweight and obese children. Ther Clin Risk Manag 2009;5:739-43.
Hosseini-Esfahani F, Mousavi Nasl Khameneh A, Mirmiran P, et al. Trends in risk factors for cardiovascular disease among Iranian adolescents: the Tehran Lipid and Glucose Study, 1999-2008. J Epidemiol 2011;21(5):319-28.
Yang S, Hwang JS, Park HK, et al. Serum lipid concentrations, prevalence of dyslipidemia, and percentage eligible for pharmacological treatment of Korean children and adolescents; data from the Korea National Health and Nutrition Examination Survey IV (2007-2009). PloS One 2012;7(12):e49253.
Hashemipour M, Soghrati M, Malek Ahmadi M. Anthropometric indices associated with dyslipidemia in obese children and adolescents: a retrospective study in Isfahan. ARYA Atheroscler 2011;7(1):31-9.
Liao Y, Mi J, Wang Y, et al. Study on the reference values of serum lipids in children aged 3-18 years old in Beijing, China. Pediatr Int 2010;52(3):472-9.
Ogden CL, Carroll MD, Curtin LR, et al. Prevalence of overweight and obesity in the United States, 1999-2004. JAMA 2006;295(13):1549-55.
Gupta N, Shah P, Nayyar S, et al. Childhood Obesity and the Metabolic Syndrome in Developing Countries. Indian J Pediatr 2013;80(Suppl 1):S28-37.
Hajian-Tilaki KO, Sajjadi P, Razavi A. Prevalence of overweight and obesity and associated risk factors in urban primary-school children in Babol, Islamic Republic of Iran. East Mediterr Health J 2011;17(2):109-14.
Moayeri H, Bidad K, Aghamohammadi A, et al. Overweight and obesity and their associated factors in adolescents in Tehran, Iran, 2004-2005. Eur J Pediatr 2006;165(7):489-93.
Olds T, Maher C, Zumin S, et al. Evidence that the prevalence of childhood overweight is plateauing: data from nine countries. Int J Pediatric Obes 2011;6(5-6):342-60.
Charakida M, Jones A, Falaschetti E, et al. Childhood obesity and vascular phenotypes: a population study. J Am Coll Cardiol 2012;60(25):2643-50.
de Onis M, Martinez-Costa C, Nunez F, et al. Association between WHO cut-offs for childhood overweight and obesity and cardiometabolic risk. Public Health Nutr 2012:16(4):625-30.
Shalitin S, Abrahami M, Lilos P, et al. Insulin resistance and impaired glucose tolerance in obese children and adolescents referred to a tertiary-care center in Israel. Int J Obes 2005;29(6):571-8.
Burke V, Beilin LJ, Simmer K, et al. Predictors of body mass index and associations with cardiovascular risk factors in Australian children: a prospective cohort study. Int J Obes 2005;29(1):15-23.
Holst-Schumacher I, Nunez-Rivas H, Monge-Rojas R, et al. Insulin resistance and impaired glucose tolerance in overweight and obese Costa Rican schoolchildren. Food Nutr Bull 2008;29(2):123-31.
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| Issue | Vol 52, No 11 (2014) | |
| Section | Articles | |
| Keywords | ||
| Cardio-metabolic risk factors Dyslipidemia Obesity Hypertriglyceridemia Hypercholesterolemia | ||
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