Blood Glucose Measurement by Glucometer in Comparison with Standard Method in Diagnosis of Neonatal Hypoglycemia
Hypoglycemia is considered as a serious risk factor in neonates. In the majority of cases, it occurs with no clinical symptoms. Accordingly, early diagnosis is extremely imperative, which can also lead to less morbidity and mortality. The aim of this study was to assess the importance of screening blood glucose using glucometer (known as a quick and cost-effective diagnostic test) in comparison with laboratory method. A total of 219 neonates at risk of hypoglycemia were included in this study. Blood glucose was measured by glucometer and laboratory. In addition glucose level of capillary blood was measured by glucometer at the same time. Sensitivity and specificity of capillary blood glucose measurement by glucometer were 83.5%, 97.5% respectively (ppv=80%), (npv=98%). Capillary blood glucose measured by glucometer has an acceptable sensitivity and specificity in measurement of neonatal blood glucose. Therefore measurement by glucometer is recommended as a proper diagnostic test.
Wilker RE. Hypoglycemia and hyperglycemia. In: Cloherty JP, Eichenwald EC, Stark AR, editors. Manual of neonatal care. 6th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2008: p. 540-9.
Kalhan SC, Devaskar AU. Disorder of Carbohydrate Metabolism. In: Martin RJ, Fanaroff AA, Walsh MC, editors. Fanaroff and Martin's, Neonatal-Perinatal Medicine: Diseases of the Fetus and Infant. 9th ed. St. Louis, MO: Mosby; 2010: p. 1497-520.
Wai chan. Neonatal hypoglycemia. UpToDate. (Accessed in Jan 2014, 24, at http://www.uptodate.com/contents/ neonatal-hypoglycemia).
Elusiyan JBE, Adeodu OO, Adejuyigbe EA. Evaluating the validity of a bedside method of detecting hypoglycemia in childern. Pediatr Emerg Care 2006;22(7):488-90.
Ho HT, Yeung WK, Young BW. Evaluation of point of care devices in the measurment of low blood glucose in neonatal practice. Arch Dis Child Fetal Neanatal Ed 2004;89(4):F356-9.
Hamid MH, ChishtiAL, MaqboolS. Clinical utility and accuracy of a blood glucose meter for the detection of neonatal hypoglycemia. J Coll Physicians Surg Pak 2004;14(4):225-8.
Anderson DG, Gleeson M, Boulton TJ. Blood glucose monitoring by childern at home: a comprasion of methods. Aust Paediatr J 1986;22(4):309-12.
Grek S, Gravenstein N, Morey TE, et al. A cost-effective screening method for preoperative hyperglycemia. Anesth Analg 2009;109(5):1622-4.
Girourd J, Forest JC, Masse J, et al. Multicenter evaluation of the Glucometer Elite XL meter, an instrument specifically desigened for use with neonates. Diabetes Care 2000;23(8):1149-53.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.