A Case with Pachyonychia Congenita and B-cell Lymphoma
-
Vitorino Modesto dos Santos
,
Thiago Pereira Loures
,
João Daniel Bringel Rego
,
Christiane Aires Teixeira
,
Kayursula Dantas de Carvalho
,
Afonso Lucas Oliveira Nascimento
Abstract
Pachyonychia congenital (PC) is a rare autosomal dominant genodermatosis characterized hyperkeratosis affecting the nails and palmoplantar areas, oral leukokeratosis, and cystic lesions. A 39-year-old woman with PC type 1 (Jadassohn-Lewandowsky syndrome) and B-cell lymphoma is described. No similar disorders or parental consanguinity were found in her family. Typical features of PC developed since her early childhood and the diagnosis of B-cell lymphoma was established seven years ago, without a clear causal relation between these entities. Despite inherent limitations of a single case, this report may contribute to PC understanding.
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| Files | ||
| Issue | Vol 52, No 7 (2014) | |
| Section | Articles | |
| Keywords | ||
| Jadassohn-Lewandowsky syndrome B-cell lymphoma Pachyonychia congenita Palmoplantar keratoderma | ||
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