Familial Amyloidosis Cutis Dyschromica: a Case Report

  • Farideh Dehghani Mail Department of Dermatology, Shahid Sadooghi University of Medical Sciences, Yazd, Iran.
  • Mohammad Ebrahimzadeh Department of Dermatology, Shahid Sadooghi University of Medical Sciences, Yazd, Iran.
  • Mansour Moghimi Department of Pathology, Shahid Sadooghi University of Medical Sciences, Yazd, Iran.
  • Mohammad Taghi Noorbala Department of Dermatology, Shahid Sadooghi University of Medical Sciences, Yazd, Iran.
Keywords:
Amyloidosis, Congo Red, Hypopigmentation, Hyperpigmentation

Abstract

Amyloidosis cutis dyschromica (ACD) is a rare form of macular amyloidosis characterized by hypo and hyperpigmented macules. Here we described a 20 year old girl with diffuse hypo and hyperpigmentation since she was four years old. Five other members of her family are also involved. Biopsy of hyperpigmented lesions revealed increase of melanin in the basal layer, pigment incontinence and amorphous eosinophilic masses stained positive with Congo red in the papillary dermis. The histopathologic findings were consistent with amyloidosis cutis dyschromica. Other investigations were normal. Dermatologists should consider amyloidosis cutis dyschromica when visit a patient with diffuse hypo and hyperpigmentation.

References

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How to Cite
1.
Dehghani F, Ebrahimzadeh M, Moghimi M, Noorbala MT. Familial Amyloidosis Cutis Dyschromica: a Case Report. Acta Med Iran. 52(2):163-165.
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Articles