Saccular Function in Otosclerosis Patients: Bone Conducted-Vestibular Evoked Myogenic Potential Analysis

  • Amin Amali Otorhinolaryngology Research Center, Imam Khomeini Educational Complex Hospital, Valieasr Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Parvane Mahdi Mail Department of Audiology, Rehabilitation Research Center, Iran University of Medical Sciences, Tehran, Iran.
  • Alireza Karimi Yazdi Otorhinolaryngology Research Center, Imam Khomeini Educational Complex Hospital, Valieasr Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Mohammad Taghi Khorsandi Ashtiyani Otorhinolaryngology Research Center, Amir Alam Educational Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Nasrin Yazdani Otorhinolaryngology Research Center, Amir Alam Educational Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Varasteh Vakili Otorhinolaryngology Research Center, Imam Khomeini Educational Complex Hospital, Valieasr Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Akram Pourbakht Department of Audiology, Rehabilitation Research Center, Iran University of Medical Sciences, Tehran, Iran.
Keywords:
Otosclerosis, Saccule, Bone Conducted-Vestibular, Myogenic

Abstract

Vestibular involvements have long been observed in otosclerotic patients. Among vestibular structures saccule has the closest anatomical proximity to the sclerotic foci, so it is the most prone vestibular structure to be affected during the otosclerosis process. The aim of this study was to investigate the saccular function in patients suffering from otosclerosis, by means of Vestibular Evoked Myogenic Potential (VEMP). The material consisted of 30 otosclerosis patients and 20 control subjects. All participants underwent audiometric and VEMP testing. Analysis of tests results revealed that the mean values of Air-Conducted Pure Tone Average (AC-PTA) and Bone-Conducted Pure Tone Average (BC-PTA) in patients were 45.28 ± 15.57 and 19.68 ± 10.91, respectively and calculated 4 frequencies Air Bone Gap (ABG) was 25.64 ± 9.95. The VEMP response was absent in 14 (28.57%) otosclerotic ears. A statistically significant increase in latency of the p13 was found in the affected ears (P=0.004), differences in n23 latency did not reach a statistically significant level (P=0.112). Disparities in amplitude of p13-n23 in between two study groups was statistically meaningful (P=0.009), indicating that the patients with otosclerosis had lower amplitudes. This study tends to suggest that due to the direct biotoxic effect of the materials released from the otosclerosis foci on saccular receptors, there might be a possibility of vestibular dysfunction in otosclerotic patients.

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How to Cite
1.
Amali A, Mahdi P, Karimi Yazdi A, Khorsandi Ashtiyani MT, Yazdani N, Vakili V, Pourbakht A. Saccular Function in Otosclerosis Patients: Bone Conducted-Vestibular Evoked Myogenic Potential Analysis. Acta Med Iran. 52(2):111-115.
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