Skin Rashes on Leg in Brucellosis: a Rare Presentation
Brucellosis is the most widespread zoonotic infection in the world. The disease is endemic in countries bordering the Mediterranean Sea. It is an important re-emerging infectious disease. This disease is closely associated with the evolution of mankind as an agrarian society linked to the practice of shepherding and popularization of animal husbandry. The patients with this disease are typically present with chills, fever, asthenia and sweating. This paper describes a patient with brucellosis and skin rashes on the leg. A 41-year-old man presented with fever, ataxia, and dysarthria. He was a shepherd. The patient reported the loss of appetite, arthralgia and weight loss during previous five months. Finally, he was diagnosed with brucellosis by positive blood culture and high titer for Brucella agglutination test. The clinical manifestation of brucellosis is very broad, ranging from asymptomatic infection to serious debilitating disease. Current patient had skin rashes on his leg. Brucellosis must be considered in the differential diagnosis of acute infections, especially if there is a history of fresh milk product ingestion and living in an endemic region.
Mantur BG, Amarnath SK. Brucellosis in India – a review. J Biosci 2008;33(4):539-47.
Refai M. Incidence and control of brucellosis in the Near East region. Vet Microbiol 2002;90(1-4):81-110.
Afify M, Al-Zahrani SH, El-Koumi MA. Brucellosis- Induced Pancytopenia in Children: a Prospective Study. Life Sci J 2013;10(1):1364-8.
Bashiri H, Sayad B, Madani SH. Study of the Assimilation Rate of Immunoenzymatic Tests and Traditional Serological Methods in the Diagnosis of Human Brucellosis. Jundishapur J Microbiol 2013;6(4): 4828.
Alpay F. Two unusual presentations of childhood brucella cases. J Curr Pediatr 2010; 8(1):39-43.
Buzgan T, Karahocagil MK, Irmak H, et al. Clinical manifestations and complications in 1028 cases of brucellosis: a retrospective evaluation and review of the literature. Int J Infect Dis 2010;14(6):469-78.
Kadanali A, Ozkurt Z, Albayrak A, et al. An unusual presentation of acute brucellosis with fever, jaundice, and maculopapular rash. Int J Infect Dis 2006;10(5):409-10.
Yildirmak Y, Palanduz A, Telhan L, et al. Bone marrow hypoplasia during Brucella infection. J Pediatr Hematol Oncol 2003;25(1):63-4.
Akcali C, Savas L, Baba M, Turunc T, Seckin D. Cutaneous Manifestations in Brucellosis:A Prospective Study. Advances in Therapy 2007; 24(4):706-11.
Milionis H, Christou L, Elisaf M. Cutaneous Manifestations in Brucellosis:Case Report and Review of the Literature. Infection 2000;28(2):124-6.
Omidi A, Jafarian AH, Erfanian M, et al. Acute Brucellosis with Pancytopenia and Maculopapular Rash. Iran J Pathol 2009;4(3):133-6.
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