Relationship between Diabetes and Intraocular Pressure

  • Mohammad Khalaj Children Growth Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
  • Sajjad Fereydooni Children Growth Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
  • Ameneh Barikani Mail Children Growth Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
Keywords:
Intraocular pressure, Diabetes, Age, Sex, Glaucoma, Presbyopia, Amblyopia

Abstract

The ophthalmologic outcomes of diabetes were important. This research is conducted to assess the relation between diabetes and intraocular pressure changes in the patients of Avicenna Hospital, compared with healthy persons referring to the facility. With cross-sectional research, 400 persons including 200 diabetics and non-diabetics were selected on a random basis over one year in 2012. Research data were collected by examination and checklists, and then analyzed by SPSS 16 statistical software. Descriptive results were extracted, and the relation between the variables were analyzed by Chi2 test, t-test, Fisher's exact test, Pearson's correlation coefficient, with P. value less than 0.05 (P < 0.05).In the group of diabetics, 37% and 63%were male and female respectively, while in non-diabetics group 47% and 53% were male and female. The mean age of diabetics patients were 54.17 ± 8.25 and non-diabetics 49.06 ± 7.26 years. Mean vision acuity of the right eye was 9.035 in the diabetics and 9.56 in the witness group. Mean intraocular pressure was 16.71 ± 1.96 mm/Hg in diabetics, and 12.86 ± 1.45 mm/Hg in non-diabetics, which showed a significant difference (t = 22.337, P = 0.001). It is advisable that the intraocular pressure of diabetics be measured and recorded on a regular basis.

References

American diabetes Association: all about diabetes. American Diabetes Association. (Accessed in March 2015, 12, at http:/www.diabetes.org/about-diabetes.jsp).

Fong DS, Aiello LP, Ferris FL, et al. Diabetic retinopathy. Diabetes Care 2004;27(10):2540-53.

Primus S, Harris A, Siesky BA. Giovanna Guidoboni. Diabetes: A risk factor for glaucoma? Br J Ophthalmol 2011;95(12):1621-2.

Javitt JC, Aiello LP. Cost effectiveness of detecting and treating diabetic retinopathy. Ann Int Med 1995;124(1 Pt2):164-9.

Nakamura M, Kanamori A, Negi A. Diabetes mellitus as a risk factor for glaucomatous optic neuropathy. Ophthalmologica 2005;219(1):1-10.

Becker B. Diabetes mellitus and primary open angle glaucoma. The XXVII Edward Jackson Memorial Lecture. Am J Ophthalmol 1971;71(1 Pt 1):1-16.

John DE, Josie MME, Danny AR, et al. Glaucoma incidence in an unselected cohort of diabetic patients: is diabetes mellitus a risk factor for glaucoma? DARTS/MEMO collaboration. Diabetes Audit and Research in Tayside Study. Medicines Monitoring Unit. Br J Ophthalmol 2000;84(11):1218-24.

Barbara EKK, Klein R, Moss SE. Incidence of self reported glaucoma in people with diabetes mellitus.Br J Ophthalmol 1997;81:743-7.

Daniel V, Paul RE, John P, editors. Vaughan & Asbury's general ophthalmology. 17th ed. New York, Ny; MxGraw- Hill; 2007: p. 212-27.

Grehn F. World health problem of glaucoma. J Glaucoma 2001;70(5):326-9.

Murray F, Thomas L, editors. Primary care of the glaucoma. 2nd ed. Philadelphia: McGraw-Hill Medical;2000.

Janghorbani M, Amini M. Cataract in typ2 diabetes mellitus in Isfahan, Iran; Incidence and risk factors. Ophthalmic Epidemiol 2004;11(5):347-58.

Lee SC1, Wang Y, Ko GT, et al. Risk factors for cataract in Chinese patients with typ2diabetes: Evidence for the influence of the aldose reductase gene. Clinical Genetics 2001;59(5):356-9.

Janghorbani M, Jones R, Allison S. Incidence of and risk factors for cataract among diabetes clinic attenders. Ophthalimic Epidemiol 2000;7(1):13-25.

Kim SI, Kim SJ. Prevalence and risk factors for cataract in persons with typ2 diabetes mellitus. Korean J Ophthalmol 2006;20(4):201-4.

Armaly MF, Kueger DE, Maunder L, et al. Biostatistical analysis of collaborative glaucoma study.l. Summary report of the risk factors for glaucomatous visual-field defects. Arch Ophthalmol 1980:98(12):2763-71.

Davidson.MB, editor. Diabetes mellitus:diagnosis and treatment. 3rd ed. New York: Churchill Livingston lnc; 1997: p. 1-9,224-6.

World health report 2002. World Health Organization. (Accessed in March 2015, 12, at whqlibdoc.who.int/.../2002/9241562072.pdf).

How to Cite
1.
Khalaj M, Fereydooni S, Barikani A. Relationship between Diabetes and Intraocular Pressure. Acta Med Iran. 53(6):363-368.
Section
Articles