Articles

Frequency and Epidemiologic Aspects of Male Infertility

Abstract

According to different geographical conditions, human health in different sub-regions of the world and cultural differences, the male factor infertility has heterogeneous causes in the world. This study was performed in an attempt to clarify the associated factors which might play a role in this respect in a group of Iranian infertile men. This study was a cross - sectional, descriptive and retrospective study. The information was obtained from the men who had attended the clinic from March 2004-2006. The factors which were studied in this research are the demographic characteristics, smoking, addiction, alcohol drinking, and exposure to lead, cimetidine and history of surgery. In 23.7 % of couples the cause of infertility was pure male factor and in 19.3 % of them the problem was related to male and female factor both. The most important associated factors for male factor included smoking (29%) and history of varicocele operation (22%). Since the quality of individual and social life is related to fertility state, it seems that more comprehensive studies on factors affecting male fertility at the community level are justified and recommended.

WHO. Infertility: A tabulation of available data on the prevalence of primary and secondary infertility. Geneva: programme on maternal and child health and family planning. Division of family health. World Health Organization. (Accessed in May 2014, 5, at http://apps.who.int/iris/bitstream/10665/59769/1/WHO_M CH_91.9.pdf?ua=1).

Leke RJ, Bassol-Mayagoitia S, Bacha AM, et al. Regional and geographical variation in infertility:effects of environmental, cultural and socioeconomic factors. Environ Health Perspect 1993;101(Suppl 2):73-80

Cates W, Farley TM, Rowe PJ. Worldwide patterns of infertility. Is Africa different? Lancet 1985;2(8455):596-8.

Forti G, Krausz C. Evaluation and treatment of the infertile couple. Clini Endocrinol Metab 1998;83(12):4177-88.

Bayasgalan G, Naranbat D, Tsedmaa B, et al. Clinical patterns and major causes of infertility in Mongolia. J Obstet Gynecol Res 2004;30 (5):386-93.

Philippov OS, Radionchenko AA, Bolotova VP, et al. Estimation of the prevalence and causes of infertility in western Siberia. Bull WHO 1998;76(2):183-7.

Dunson DB, Baird DD, Colombo B. Increased infertility with age in men and women. Obstet Gynecol 2004;103(1):51-6.

Hassa H, Yildirim A, Can C, et al. Effect of smoking on semen parameters of men attending an infertility clinic. Clin Exp Obstet Gynecol 2006;33(1):19-22.

Viskum S, Rabjerg L, Jorgensen PJ, et al. Impairment in semen quality associated with decreasing occupational lead exposure. Am J In Med 1999;35(3):257-63.

Weber RF, De Baat C. Male Fertility. Possibly affected by occupational exposure to mercury. Ned Tijdschv Tandheelked 2000;107(12):495-8.

Emanuele MA, Emanuel NV. Alcohol's effect on male reproduction. Alcohol Health Res World 1998;22(3):195-201.

Okada H, Iwamoto T, Fujioka H, et al. Hyperprolactinemia among infertile patients its effect on sperm functions. Andrologia 1996;28(4):197-202.

D' Agostino S, Belloli GP. Primary varicocele: An underestimated pathology in childhood and adolescence. Pediatr Med Chir 1992;14(1):7-12.

Austoni E, Cazzaniga A, Gatti G, et al. Varicocele and its repercussion on infertility. Indication and limitations of surgical intervention. Arch Ital Urol Androl 1998;70(2):103-7.

Sheynkin YR, Hendin BN, Schlegel PN, et al. Microsurgical repair of iatrogenic injury to the vas deferens. J Urol 1998;159(1):139-41.

Fitzgibbons RJ. Can we be sure Polypropylene Mesh Causes Infertility? Ann Surg 2005;241(4):559-61.

Thonneau P, Marchand S, Tallec A, et al. Incidence and main causes of infertility in a resident population (1,850,000) of three French regions (1988-1989). Hum Reprod 1991;6(6):811-6.

Matsuda T, Muguruma K, Hiura Y, et al. Seminal tract obstruction caused by childhood inguinal herniorrhaphy: results of microsurgical reanastomosis. J Urol 1998;159(3):837-40.

Sigman M, Jonathan P, Jarow S. Male infertility. In: Wein AJ, Kavoussi LR, Novick AC, et al, editors. Campbell- Walsh Urology. 9th ed. Philadelphia: WB Saunders; 2007: p. 609-50.

Turek PJ, Pera RA. Current and future genetic screening for male infertility. Urol Clin North Am 2002;29(4):767-92.

Zhang JP, Meng AY, Zhang LJ, et al. Study of correlation and effect of smoking on semen quality of men. Zhoughna Nan Ke Xue 2002;8(1):35-7.

Mostafa T. Cigarette smoking and male infertility. J Adv Res 2010;1(3):179-86.

Miyaoka R, Esteves SC. A Critical Appraisal on the Role of Varicocele in Male Infertility. Adv Urol 2012;1(1):1-9.

Schauer I, Madersbacher S, Jost R, et al. The impact of varicocelectomy on sperm parameters: a meta-analysis. J Urol 2012;187(5):1540-7.

Shamsa A, Nademi M, Aqaee M, et al. Complications and the effect of varicocelectomy on semen analysis, fertility, early ejaculation and spontaneous abortion. Saudi J Kidney Dis Transpl 2010;21(6):1100-5.

Ragni G, De Lauretis L, Gambaro V, et al. Semen evaluation in heroin and methadone addicts. Acta Eur Fertil 1985;16(4):245-9.

Tsujimura A, Matsumiya K, Takahashi T, et al. Effect of lifestyle factors on infertility in men. Arch Androl 2004;50(1):15-7.

Stadel R, Yang J, Nalwalk JW, et al. High-affinity binding of [3H] cimetidine to a heme-containing protein in rat brain. Drug Metab Dispos 2008;36(3):614-21.

Files
IssueVol 53, No 4 (2015) QRcode
SectionArticles
Keywords
Smoking Varicocele Male infertility

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Sohrabvand F, Jafari M, Shariat M, Haghollahi F, Lotfi M. Frequency and Epidemiologic Aspects of Male Infertility. Acta Med Iran. 1;53(4):231-235.