The Effects of Secondhand Smoke Exposure on Infant Growth: a Prospective Cohort Study
Mother's and infant exposure to cigarette smoke is one of the most important public health problems. There is no study in Iran evaluating the impact of cigarette smoke on infant growth and development. The purpose of this study was to determine the effects of cigarette. This prospective cohort study was conducted on 51 cigarette smoke-exposed infants (exposed group) and 51 non-exposed infants (non-exposed group). They were evaluated for weight, height and head circumference three times; five to seven days, two months and four months after birth. Urine samples were also collected in each turn. Exposure to secondhand smoke was assessed through questionnaires and urinary cotinine levels. The analysis was performed using an independent t-test, Mann-Whitney U test, chi-square and Fisher's exact and Kappa tests. Mean urinary cotinine level in the exposed group was 38.57±2.85 ng/mg creatinine at baseline, 86.95±1.16 at two months and 63.32±2.08 at four months of age. These indicated a gradual reduction of exposure from two to four months. The weight and height of the exposed group were significantly lower than the non-exposed group (P< 0.001) at two and four months after birth. The results of the present study showed that the exposure to secondhand smoke during infancy may lead to weight and height growth reduction in the first four months of life.
The Tobacco Health Toll. Nasr city Egypt: Publication of World Health Organization, Regional Office for eastern Mediterranean. World Health Organization (Accessed in Apr 2014, 14, at http://www.emro.who.int/TFI/PDF/TobaccoHelthToll.pdf).
Chen R, Tunstall-Pedoe H, Tavandale R. Environmental Tobacco Smoke And Lung Function In Employees Who Never Smoked: The Scottish MONICA Study. Occup Environ Med 2001;58(9);563-8.
InheritingtheWorld: The atlas of children's health and the environment. World Health Organization. (Accessed in Apr 2014, 18, at http://www.archive.org/texts/flipbook/flippy.php?id=inheri tingworlda00gordrich).
Meysamie A, Ghaletaki R, Haghazali M, et al. Pattern of Tobacco use Among Iranian Adult Population: results of the national Survey of Risk Factors of Non-Communicable Diseases (SuRFNCD-2007). Tob Control 2010;19(2):125-8.
Baheiraeia A, Banihosseini SZ, Heshmat R, et al. Association of self-reported passive smoking in pregnant women with cotinine level of maternal urine and umbilical cord blood at delivery. Paediatr Perinat Epidemiol 2012;26(1):70-6.ppe_
Baheiraei A, Kharaghani R, Mohsenifar A, et al. Reduction of Secondhand Smoke Exposure Among Healthy Infacnts In Iran: Randomized Controlled Trial. Nicotine Tob Res 2011;13(9):840-7.
Benowitz NL. Cotinine as a Biomarker of EnvironmentalTobacco Smoke Exposure. Epidemiol Rev 1996;18(2):188-204.
Berlanga MR, Salazar G, Garcia C, et al. Maternal Smoking Effects on Infant Growth. Food Nutr Bull 2002;23(3 Suppl):142-5.
The Health Consequences of Involuntary Exposure to Tobacco Smoke: A Report of the Surgeon General. Atlanta, G.A. U.S Department of Health and Human Services. (Accessed in Apr 2006, 18, http://www.surgeongeneral.gov/library/reports/secondhand smoke/fullreport.pdf).
Ong KK, Preece MA, Emmet PM, et al. Size at Birth and Early Childhood Growth in Relation to Maternal Smoking, Parity and Infant Breast-Feeding: Longitudinal Birth Cohort Study and Analysis. Pediatr Res 2002;52(6):863-7.
Vielwerth SE, Jensen RB, Larsen T, et al. The Impact of Maternal Smoking on Fetal and Infant Growth. Early Hum Dev 2007;83(8):491-5.
Conter V, Cortinovis I, Rogari P, et al. Weight Growth in Infants Born to Mothers, Who smoked during pregnancy. BMJ 1995;310(6952):768-71
Fenercioglu AK, Tamer I, Kratekin G, et al. Impaired Postnatal Growth of Infants Prenatally Exposed to Cigarette Smoking. Tohoku J Exp Med 2009;218(3):221-8.
Florescu A, Ferrence R, Einarson T, et al. Methods for Quantification of Exposure to Cigarette Smoking and Environmental Tobacco Smoke: Focus on Developmental Toxicology. Ther Drug Monit 2009;31(1):14-30.
Grote V, Vik T, Von Kries R, et al. Maternal Postnatal Depression And Child Growth: A European Cohort Study. BMC Pediatr 2010;10(1):14.
Hindmarsh PC, Geary MP, Rodeck CH, et al. Factors Predicting Ante- and Postnatal Growth. Pediatric Research, 2008;63(1):99-102.
Kanellopus TA, Varvarigou AA, Karatza AA, et al. Course of Growth during the First 6 Years in Children Exposed in Utero to Tobacco Smoke. Eur J Pediatr 2007;166(7):685-92.
Kharaghani R. Effect of Counselling with Smoker Parents on Infant’s Exposure to Secondhand Smoke on Urinary Cotinine and Parent's Report [Dissertation]. Tehran Univ Med Sci., 2009.
Kyu H, Georgiades K, Boyle MH. Maternal Smoking, Biofuel Smoke Exposure and Child Height-for-age in Seven Developing Countries. Int J Epidemiol 2009;38(5):1342-50
Leonardi-Bee J, Smyth A, Britton J, et al. Environmental Tobacco Smoke and Fetal Health: Systematic Review and Meta-analysis. Arch Dis Chil Fetal Neonatal Ed 2008;93(5):F351-61.
Matt GE, Bernert JT, Hovell MF. Measuring Secondhand Smoke Exposure in Children: An Ecological Measurement Approach. J Pediatr Psychol 2008;33(2):156-75.
Chamari M, Djazayery A, Jalali M, et al. The Effect of Daily Consumption of Probiotic and Conventional Yogurt on Some Oxidative Stress Factors in Plasma of Young Healthy women. Int J Vitam Nutr Res 2007;77(2):79-88.
Mendez M A, Torrent M, Ferrer C, et al. Maternal Smoking Very Early In Pregnancy Is Related to Child Overweight. Am J Clin Nutr 2008;87(6):1906-13.
Sowan NA, Stemmer ML. Effect of Maternal Prenatal Smoking on Infant Growth and Development of Obesity. J Perinat Educ 2000; 9(3): 22-29.
Braun JM, Daniels JL, Poole C, et al. Prenatal environmental tobacco smoke exposure and early childhood body mass index. Paediatr Perinat Epidemiolm2010;24(6):524-34.
Oken E, Levitan EB, Gillman MW. Maternal smoking during pregnancy and child overweight: systematic review and meta-analysis. Int J Obes 2008;32(2):201-10.
Vaglenova J, Birru S, Piniella NM, et al. An Assessment of the Long-term Developmental and Behavioral Teratogenicity of Prenatal Nicotine Exposure. Behav BrainnRes 2004;150(1-2):159-70.
Yılmaz G, Hızli A, Karacan C, et al. Effect of Passive Smoking on Growth and Infection Rates of Breast-fed and Non-breast-fed Infants. Pediatr Int 2009;51(3):352-8.
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