Interaural Difference Values of Vestibular Evoked Myogenic


Migraine is a neurologic disease, which often is associated with a unilateral headache. Vestibular abnormalities are common in migraine. Vestibular evoked myogenic potentials (VEMPs) assess otolith function in particular functional integrity of the saccule and the inferior vestibular nerve. We used VEMP to evaluate if the migraine headache can affect VEMP asymmetry parameters. A total of 25 patients with migraine (22 females and 3 males) who were diagnosed according to the criteria of IHS-1988 were enrolled in this cross-sectional study. Control group consisted of 26 healthy participants (18 female and 8 male), without neurotological symptoms and history of migraine. The short tone burst (95 dB nHL, 500 Hz) was presented to ears. VEMP was recorded with surface electromyography over the contracted ipsilateral sternocleidomastoid (SCM) muscle. Although current results showed that the amplitude ratio is greater in migraine patients than normal group, there was no statistical difference between two groups in mean asymmetry parameters of VEMP. Asymmetry measurements in vestibular evoked myogenic potentials probably are not indicators of unilateral deficient in saccular pathways of migraine patients.

Afridi SK, Matharu MS, Lee L, et al. A PET study exploring the laterality of brainstem activation in migraine using glyceryl trinitrate. Brain 2005;128(Pt 4):932-9.

Allena M, Magis D, Pasqua VD, et al. The vestibulo-collic reflex is abnormal in migraine. Cephalalgia 2007;27(10):1150-5.

Harno H, Hirvonen T, Kaunisto MA, et al. Subclinical vestibulocerebellar dysfunction in migraine with and without aura. Neurology 2003;61(12):1748-52.

Brantberg K, Fransson PA. Symmetry measures of vestibular evoked myogenic potentials using objective detection criteria. Scand Audiol 2001;30(3):189-96.

Kim S, Lee HS, Kim JS. Medial vestibulospinal tract lesions impair sacculo-collic reflexes. J Neurol 2010;257(5):825-32.

Lee KJ, Kim MS, Son EJ, et al. The Usefulness of Rectified VEMP. Clin Exp Otorhinolaryngol 2008;1(3):143-7.

Brantberg K. Vestibular evoked myogenic potentials (VEMPs): usefulness in clinical neurotology. Semin Neurol 2009;29(5):541-7.

Akin FW, Murnane OD. Vestibular evoked myogenic potentials: a preliminary report. J Am Acad Audiol 2001;12(9):445-52.

Zapala D. The VEMP: Ready for the clinic. Hearing J 2007;60(3):10-20.

McCaslin DL, Jacobson GP, Harry T. The Recordability of Two Sonomotor Responses in Young Normal Subjects. J Am Acad Audiol 2008;19(7):542-7.

Heide G, Luft B, Franke J, et al. Brainstem representation of vestibular evoked myogenic potentials. Clin Neurophysiol 2010;121(7):1102-8.

Rosengren SM, Welgampola MS, Colebatch JG. Vestibular evoked myogenic potentials: past, present and future. Clin Neurophysiol 2010;121(5):636-51.

Ferber-Viart C, Dubreuil C, Duclaux R. Vestibular evoked myogenic potentials in humans: a review. Acta Otolaryngol 1999;119(1):6-15.

Zhou G, Cox LC. Vestibular evoked myogenic potentials: history and overview. Am J Audiol 2004:13(2):135-43.

Liao LJ, Young YH. Vestibular evoked myogenic potentials in basilar artery migraine. Laryngoscope 2004;114(7):1305-9.

Baier B, Stieber N, Dieterich M. Vestibular-evoked myogenic potentials in vestibular migraine. J Neurol 2009;256(9):1447-54.

Kamali B, Hajiabolhassan F, Fatahi J, et al. Effects of Diabetes Mellitus Type Ι with or without Neuropathy on Vestibular Evoked Myogenic Potentials. Acta Med Iran 2013;51(2):107-12.

Park HJ, Lee IS, Shin JE, et al. Frequency-tuning characteristics of cervical and ocular vestibular evoked myogenic potentials induced by air-conducted tone bursts. Clin Neurophysiol 2010;121(1):85-9.

Vanspauwen R, Wuyts FL, Van De Heyning PH. Validity of a new feedback method for the VEMP test. Acta Otolaryngol 2006;126(8):796-800.

Sandhu JS, Bell SL. Effects of eye position on the vestibular evoked myogenic potential. Acta Otolaryngol 2009;129(2):175-8.

Hall JW, editor. Electrically Evoked and Myogenic Response. In: New Handbook of Auditory evoked responses. 2nd ed. Boston, Mass: Perason education Inc; 2007: p. 581-628.

Felipe L, Santos MAR, Gonçalves DU. Vestibular evoked myogenic potential (Vemp): evaluation of responses in normal subjects. Pro Fono 2008;20(4):249-54.

Young YH, Kuo SW. Side-difference of vestibular evoked myogenic potentials in healthy subjects. Hear Res 2004;198(1-2):93-8.

Welgampola MS, Colebatch JG. Characteristics and clinical applications of vestibular-evoked myogenic potentials. Neurology 2005;64(10):1682-8.

Lee H, Lopez I, Ishiyama A, et al. Can migraine damage the inner ear? Arch Neurol 2000;57(11):1631-4.

Parker W. Migraine and the vestibular system in adults. Am J Otol 1991;12(1):25-34.

Weiller C, Mav A, LlMmroth V, et al. Brain stem activation in spontaneous human migraine attacks. Nat Med 1995;1(7):658-60.

IssueVol 53, No 1 (2015) QRcode
Migraine Vestibular evoked myogenic potential Vestibular asymmetry Laterality of headache

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
Moallemi M, Hajiabolhassan F, Fatahi J, Abolfazli R, Jalaei S, Khamseh F. Interaural Difference Values of Vestibular Evoked Myogenic. Acta Med Iran. 1;53(1):33-38.