Case Report

A Case of Advanced Unicentric Retroperitoneal Castleman's Disease, Associated With Psoriasis


We present here a 32-year-old male with advanced lately diagnosed, right sided retroperitoneal mass, which had been already treated due to progressive muco-cutaneous lesions clinically consistent with psoriasis, during recent four years. The advanced retroperitoneal mass resected surgically and reported as hyaline-vascular castleman disease with a dense focus of coarse calcification, on histopathology. Association of psoriasis and castlman disease is discussed in this case report. 

Abdessayed N, Bdioui A, Ammar H, Gupta R, Mhamdi N, Guerfela M, and Mokni M. Retroperitoneal unicentric Castleman’s disease: A case report. Int J Surg Case Rep.2017; 31: 54–57.

Choh NA, Qayoom S, Shaheen F, Malik RA, Rabbani I, Gojwari T. Retroperitoneal Castlemans Disease associated with Paraneoplastic Pemphigus. Hematol Oncol Stem Cell Ther 2014;7:93-6.

DePond WD. Lymph nodes - not lymphoma, Inflammatory disorders (non-infectious), PathologyOutlines. (Accessed December 2016, 30, at olymphoidhyperplasiawitheosinophili.html).

Bonekamp D, Horton KM, Hruban RH, Fishman EK.Castleman Disease: The Great Mimic. Radio Graphics 2011;31:1793-807.

Chronowski GM, Ha CS, Wilder RB, Cabanillas F, Manning J, Cox JD. Treatment of unicentric and multicentric Castleman disease and the role of radiotherapy. Cancer 2001;92:670-6.

Mimouni D, Anhalt GJ, Lazarova Z, Aho S, Kazerounian S, Kouba DJ, Mascaro JM Jr., et al. Paraneoplastic pemphigus in children and adolescents. Br J Dermatol 2002;147:725-32.

Would you have Castleman's disease when you have Psoriasis? (Accessed December 2016, 30, at Http://'s disea se).

Silva JA, Mesquita Kde C, Igreja AC, Lucas IC, Freitas AF, Oliveira SM, et al. Paraneoplastic cutaneous manifestations: concepts and updates. An Bras Dermatol 2013;88:9-22.

Sears AV, Laftah Z, Al-Shakarchi I, Salisbury JR, Marcus R, Creamer D. Diagnosis of Castleman disease in a patient treated with prolonged anti-TNF biologic therapy for psoriasis and psoriatic arthritis. J Am Acad Dermatol 2015;72:1615.

IssueVol 55, No 4 (2017) QRcode
SectionCase Report(s)
Castleman’s disease Lymphoproliferative disorders Psoriasis Retroperitoneal neoplasm

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
Mohagheghi MA, Omranipur R, Ensani F, Ghannadan A, Shahriaran S, Samiee F, Sedighi Z. A Case of Advanced Unicentric Retroperitoneal Castleman’s Disease, Associated With Psoriasis. Acta Med Iran. 2017;55(4):277-279.