Original Article

The Comparison of WHOQOL-BREF with Disease Specific Heath Related Quality of Life Questionnaire in Irritable Bowel Syndrome

Abstract

Irritable Bowel Syndrome (IBS) is one of the most common gastrointestinal disorders particularly affecting the quality of life (QOL). Evaluating QOL in IBS patients is a valuable method of defining a psychobiological pattern of disease. Various disease specific and general instruments are now available to measure health-related QOL (HRQOL) in IBS patients. Though, no comparison has been made between these tools especially in non-western countries. We aimed to compare QOL measures between two specific and general QOL questionnaires in a sample of Iranian IBS patients. A total of 250 IBS patients were diagnosed based on Rome III criteria (mean age 29.6 ± 9.6 years). HRQOL was assessed using disease specific quality of life for IBS (IBS-QOL) and generic World Health Organization Quality of Life-BREF (WHOQOL-BREF) questionnaires. Patients also completed Speilberger`s “State/Trait Anxiety Inventory” and “Beck Depression Inventory-II” for the evaluation of anxiety and depression symptoms. The severity of symptoms was independently associated with HRQOL in patients using WHOQOL-BREF and IBS-QOL (r = -0.48 and -0.39 respectively, P < 0.001). In linear regression analysis, a strong correlation was observed between the HRQOL scores of IBS-QOL and the WHOQOL-BREF questionnaires (standard β = 0.86 (95%CI: 1.15 - 1.44), P value < 0.001). Controlling for anxiety and depression symptoms did not influence the strength of observed correlation. The WHOQOL-BREF is a psychometrically sound, rapid and convenient instrument whose HRQOL measure is as valid and accurate as the disease-specific IBS-QOL questionnaire. It seems reasonable to use the WHOQOL-BREF alongside the IBS-QOL.

Chang FY, Lu CL, Chen TS. The current prevalence of irritable bowel syndrome in Asia. J Neurogastroenterol Motil 2010;16(4):389-400.

Singh P, Agnihotri A, Pathak MK, et al. Psychiatric, somatic and other functional gastrointestinal disorders in patients with irritable bowel syndrome at a tertiary care center. J Neurogastroenterol Motil 2012;18(3):324-31.

Makharia GK, Verma AK, Amarchand R, et al. Prevalence of irritable bowel syndrome: a community based study from Northern India. J Neurogastroenterol Motil 2011;17(1):82-7.

Choung RS, Locke GR 3rd. Epidemiology of IBS. GastroenterolClin North Am 2011;40(1):1-10.

Sandler RS, Everhart JE, Donowitz M, et al. The burden of selected digestive diseases in the United States. Gastroenterology 2002;122(5):1500-11.

Mönnikes H. Quality of life in patients with irritable bowel syndrome. J ClinGastroenterol 2011; 45(Suppl):S98-101.

Inadomi JM, Fennerty MB, Bjorkman D. Systematic review: the economic impact of irritable bowel syndrome. Aliment Pharmacol Ther 2003;18(7):671-82.

Maxion-Bergemann S, Thielecke F, Abel F, et al. Costs of irritable bowel syndrome in the UK and US. Pharmacoeconomics 2006;24(1):21-37.

Rapps N, van Oudenhove L, Enck P, et al. Brain imaging of visceral functions in healthy volunteers and IBS patients. J Psychosom Res 2008;64(6):599-604.

Musial F, Häuser W, Langhorst J, et al. Psychophysiology of visceral pain in IBS and health. J Psychosom Res 2008;64(6):589-97.

Whitehead WE, Palsson O, Jones KR. Systematic review of the comorbidity of irritable bowel syndrome with other disorders: what are the causes and implications? Gastroenterology 2002;122(4):1140-56.

Vandvik PO, Wilhelmsen I, Ihlebaek C, et al. Comorbidity of irritable bowel syndrome in general practice: a striking feature with clinical implications. Aliment Pharmacol Ther 2004;20(10):1195-203.

Riedl A, Schmidtmann M, Stengel A, et al. Somatic comorbidities of irritable bowel syndrome: a systematic analysis. J Psychosom Res 2008;64(6):573-82.

Gros DF, Antony MM, McCabe RE, et al. Frequency and severity of the symptoms of irritable bowel syndrome across the anxiety disorders and depression. J Anxiety Disord 2009;23(2):290-6.

Jamali A, Tofangchiha S, Jamali R, et al. Medical students' healthrelated quality of life: roles of social and behavioural factors. Med Educ 2013;47(10):1001-12.

Lydiard RB, Fossey MD, Marsh W, et al. Prevalence of psychiatric disorders in patients with irritable bowel syndrome. Psychosomatics 1993;34(3):229-34.

Whorwell PJ. Hypnotherapy for irritable bowel syndrome: the response of colonic and noncolonic symptoms. J Psychosom Res 2008;64(6):621-3.

Oerlemans S, van Cranenburgh O, Herremans PJ, et al. Intervening on cognitions and behavior in irritable bowel syndrome: A feasibility trial using PDAs. J Psychosom Res 2011;70(3):267-77.

Jones M, Koloski N, Boyce P, et al. Pathways connecting cognitive behavioral therapy and change in bowel symptoms of IBS. J Psychosom Res 2011;70(3):278-85.

El-Serag HB, Olden K, Bjorkman D. Health-related quality of life among persons with irritable bowel syndrome: a systematic review. Aliment Pharmacol Ther 2002;16(6):1171-85.

Aghamolaei T, Tavafian SS, Zare S. Health related quality of life in elderly people living in Bandar Abbas, Iran: a population-based study. Acta Med Iran 2010;48(3):185-91.

Amouretti M, Le Pen C, Gaudin AF, et al. Impact of irritable bowel syndrome (IBS) on health-related quality of life (HRQOL). Gastroenterol Clin Biol 2006;30(2):241-6.

Frank L, Kleinman L, Rentz A, et al. Health related quality of life associated with irritable bowel syndrome: comparison with other chronic diseases. Clin Ther 2002;24(4):675-89.

Drossman D, Morris CB, Hu Y, et al. Characterization of health related quality of life (HRQOL) for patients with functional bowel disorder (FBD) and its response to treatment. Am J Gastroenterol 2007;102(7):1442-53.

Wilson A, Longstreth GF, Knight K, et al. Quality of life in managed care patients with irritable bowel syndrome. Manag Care Interface 2004;17(2):24-8.

Jamali R, Jamali A, Poorrahnama M, et al. Evaluation of health related quality of life in irritable bowel syndrome patients. Health Qual Life Outcomes 2012;10(1):12.

Riedl A, Schmidtmann M, Stengel A, et al. Somatic comorbidities of irritable bowel syndrome: a systematic analysis. J Psychosom Res 2008;64(6):573-82.

American College of Gastroenterology Task Force on Irritable Bowel Syndrome, Brandt LJ, Chey WD, Foxx- Orenstein AE, et al. An evidence-based position statement on the management of irritable bowel syndrome. Am J Gastroenterol 2009;104(Suppl 1):S1-35.

Faresjö A, Grodzinsky E, Johansson S, et al. A populationbased case-control study of work and psychosocial problems in patients with irritable bowel syndrome-- women are more seriously affected than men. Am J Gastroenterol 2007;102(2):371-9.

Xiong LS, Chen MH, Wang WA, et al. Evaluation of the quality of life of patients with irritable bowel syndrome. Zhonghua NeiKe Za Zhi 2004;43(5):356-9.

Park JM, Choi MG, Kim YS, et al. Quality of life of patients with irritable bowel syndrome in Korea. Qual Life Res 2009;18(4):435-46.

Akehurst RL, Brazier JE, Mathers N, et al. Health-related quality of life and cost impact of irritable bowel syndromemin a UK primary care setting. Pharmacoeconomics 2002;20(7):455-62.

Lackner JM, Gudleski GD, Zack MM, et al. Measuring health-related quality of life in patients with irritable bowel syndrome: can less be more? Psychosom Med 2006;68(2):312-20.

Drossman DA, Creed FH, Olden KW, et al. Psychosocial aspects of the functional gastrointestinal disorders. In: Drossman DA, Corazziari E, Talley NJ, et al, editors. Rome II. The Functional Gastrointestinal Disorders. 2nd ed. McLean, VA: Degnon Associates; 2000: p. 157-245.

Detmar SB, Muller MJ, Schornagel JH, et al. Health related quality-of-life assessments and patient physician communication: a randomized controlled trial. JAMA 2002;288(23):3027-34.

The WHOQOL Group. Development of the World Health Organization WHOQOL-BREF quality of life assessment. Psychol Med 1998;28(3):551-8.

Longstreth GF, Thompson WG, Chey WD, et al. Functional bowel disorders. Gastroenterology 2006;130(5):1480-91.

Patrick DL, Drossman DA, Frederick IO, et al. Quality of life in persons with irritable bowel syndrome: development and validation of a new measure. Dig Dis Sci 1998;43(2):400-11.

Drossman DA, Patrick DL, Whitehead WE, et al. Further validation of the IBS-QOL: a disease specific quality of life questionnaire. Am J Gastroenterol 2000;95(4):999-1007.

Patrick DL, Drossman DA, Frederick IO. A Quality of Life Measure for persons with Irritable Bowel Syndrome (IBSQOL): User’s Manual and Scoring Diskette for United States Version. Seattle: University of Washington; 1997.

Beck AT, Steer RA, Ball R, et al. Comparison of Beck Depression Inventories -IA and -II in psychiatric outpatients. J Pers Assess 1996;67(3):588-597.

Beck AT, Steer RA, Brown GK. Manual for the Beck Depression Inventory-II. San Antonio, TX: Psychological Corporation; 1996.

Speilberger CD, Gorsuch RL, Lushene RE. Manual for the State-Trait Anxiety Inventory. Palo Alto, CA: Consulting Psychologist Press; 1970.

Gholamrezaei A, Zolfaghari B, Farajzadegan Z, et al. Linguistic validation of the Irritable Bowel Syndrome- Quality of Life Questionnaire for Iranian patients. Acta Med Iran 2011;49(6):390-5.

Usefy AR, Ghassemi GR, Sarrafzadegan N, et al. Psychometric properties of the WHOQOL-BREF in an Iranian adult sample. Community Ment Health J 2010;46(2):139-47.

Ghassemzadeh H, Mojtabai R, Karamghadiri N, et al. Psychometric properties of a Persian-language version of the Beck Depression Inventory--Second edition: BDI-IIPERSIAN. Depress Anxiety 2005;21(4):185-92.

Kempen GI, Jelicic M, Ormel J. Personality, chronic medical morbidity, and health-related quality of life among older persons. Health Psychol 1997;16(6):539-46.

Kanazawa M, Drossman DA, Shinozaki M, et al. Translation and validation of a Japanese version of theirritable bowel syndrome-quality of life measure (IBSQOL- J). Biopsychosoc Med 2007;1(1):6.

Stewart AL, Greenfield S, Hays RD, et al. Functional status and well-being of patients with chronic conditions. Results from the Medical Outcomes Study. JAMA 1989;262(7):907-13.

Hays RD, Anderson R, Revicki D. Psychometric considerations in evaluating health-related quality of life measures. Qual Life Res 1993;2(6):441-9.

Spiegel BM, Gralnek IM, Bolus R, et al. Clinical determinants of health-related quality of life in patients with irritable bowel syndrome. Arch Intern Med 2004;164(16):1773-80.

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IssueVol 53, No 11 (2015) QRcode
SectionOriginal Article(s)
Keywords
Irritable Bowel Syndrome Primary Health Care Quality of Life Questionnaires

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How to Cite
1.
Jamali R, Biglari M. The Comparison of WHOQOL-BREF with Disease Specific Heath Related Quality of Life Questionnaire in Irritable Bowel Syndrome. Acta Med Iran. 2015;53(11):717-724.