Management of Retinal Vein Occlusion, Who Is Responsible?

  • Mohamadreza Aghamirsalim Department of Ophthalmology, Rasoul-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran. AND Students’ Scientific Research Center (SSRC), Exceptional Talent Development Center (ETDC), Tehran University of Medical Sciences, Tehran, Iran.
  • Reza Sorbi Mail Students’ Scientific Research Center (SSRC), Exceptional Talent Development Center (ETDC), Tehran University of Medical Sciences, Tehran, Iran.
  • Mohammadreza Naderian Students’ Scientific Research Center (SSRC), Exceptional Talent Development Center (ETDC), Tehran University of Medical Sciences, Tehran, Iran. AND Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
  • Sudha Cugati Department of Ophthalmology, University of Adelaide, Adelaide, Australia.
  • Marianne Levon Shahsuvaryan Department of Ophthalmology, Yerevan State Medical University, Armenia.
  • Maryam Ghazizadeh Hashemi Department of Psychiatry, Rasoul-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Keywords:
Ophthalmologists, Retinal vein occlusion, Questionnaire, Hyperlipidemias, Hypertension

Abstract

Retinal vein occlusion (RVO) is a common retinal vascular occlusive disorder and is associated with a variety of systemic risk factors. The aim of this study was to investigate whether the underlying diseases were evaluated and managed appropriately by ophthalmologists. We performed a study of 1344 patients with retinal vein occlusion (RVO). Patients were evaluated with a questionnaire including ten closed questions to determine whether ophthalmologists evaluated and informed their patients about the underlying systemic diseases. None of the patients’ homocysteine levels were measured. Only a small percentage of the patients were asked about the history of thrombotic diseases or family history of thrombotic diseases. We believe that most ophthalmologists are still not entirely convinced of their responsibility of managing the underlying predisposing factors of RVO. Ophthalmologists should either manage or engage other healthcare providers in the management of RVO to guarantee the patient the best care.

References

Prisco D, Marcucci R, Bertini L, Gori AM. Cardiovascular and thrombophilic risk factors for central retinal vein occlusion. European journal of internal medicine. 2002;13(3):163-9.

Parodi MB. Central vein occlusion and laser treatment. Archives of ophthalmology. 1995;113(5):555.

Hayreh SS. Prevalent misconceptions about acute retinal vascular occlusive disorders. Progress in retinal and eye research. 2005;24(4):493-519.

Recchia FM, Brown GC. Systemic disorders associated with retinal vascular occlusion. Current opinion in ophthalmology. 2000;11(6):462-7.

Hayreh SS, Zimmerman B, McCarthy MJ, Podhajsky P. Systemic diseases associated with various types of retinal vein occlusion. American journal of ophthalmology. 2001;131(1):61-77.

Cugati S, Wang JJ, Rochtchina E, Mitchell P. Ten-year incidence of retinal vein occlusion in an older population: the Blue Mountains Eye Study. Archives of ophthalmology. 2006;124(5):726-32.

Prisco D, Bertini L, Marcucci R, Poli D. [Retinal vein occlusions: diseases for the internist?]. Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna. 2000;15(1):75-84.

Risk factors for branch retinal vein occlusion. The Eye Disease Case-control Study Group. American journal of ophthalmology. 1993;116(3):286-96.

Rath EZ, Frank RN, Shin DH, Kim C. Risk factors for retinal vein occlusions. A case-control study. Ophthalmology. 1992;99(4):509-14.

Shahsuvaryan ML, Melkonyan AK. Central retinal vein occlusion risk profile: a case-control study. European journal of ophthalmology. 2003;13(5):445-52.

Wong TY, Larsen EK, Klein R, Mitchell P, Couper DJ, Klein BE, et al. Cardiovascular risk factors for retinal vein occlusion and arteriolar emboli: the Atherosclerosis Risk in Communities & Cardiovascular Health studies. Ophthalmology. 2005;112(4):540-7.

McIntosh RL, Rogers SL, Lim L, Cheung N, Wang JJ, Mitchell P, et al. Natural history of central retinal vein occlusion: an evidence-based systematic review. Ophthalmology. 2010;117(6):1113-23.e15.

Prisco D, Marcucci R. Retinal vein thrombosis: risk factors, pathogenesis and therapeutic approach. Pathophysiology of haemostasis and thrombosis. 2002;32(5-6):308-11.

Bertelsen M, Linneberg A, Christoffersen N, Vorum H, Gade E, Larsen M. Mortality in patients with central retinal vein occlusion. Ophthalmology. 2014;121(3):637-42.

Roy R, Saurabh K, Jain AB, Das D, Majumder AK, Lobo A. Central retinal vein occlusion as a presenting feature in a young patient with protein S deficiency. Clinical & experimental optometry : journal of the Australian Optometrical Association. 2015;98(2):190-1.

Risse F, Frank RD, Weinberger AW. Thrombophilia in patients with retinal vein occlusion: a retrospective analysis. Ophthalmologica Journal international d'ophtalmologie International journal of ophthalmology Zeitschrift fur Augenheilkunde. 2014;232(1):46-52.

Cugati S, Wang JJ, Knudtson MD, Rochtchina E, Klein R, Klein BE, et al. Retinal vein occlusion and vascular mortality: pooled data analysis of 2 population-based cohorts. Ophthalmology. 2007;114(3):520-4.

Martin SC, Butcher A, Martin N, Farmer J, Dobson PM, Bartlett WA, et al. Cardiovascular risk assessment in patients with retinal vein occlusion. The British journal of ophthalmology. 2002;86(7):774-6.

Tsaloumas MD, Kirwan J, Vinall H, O'Leary MB, Prior P, Kritzinger EE, et al. Nine year follow-up study of morbidity and mortality in retinal vein occlusion. Eye (London, England). 2000;14(Pt 6):821-7.

Yau JW, Lee P, Wong TY, Best J, Jenkins A. Retinal vein occlusion: an approach to diagnosis, systemic risk factors and management. Internal medicine journal. 2008;38(12):904-10.

Dursun A, Ozturk S, Yucel H, Ozec AV, Dursun FG, Toker MI, et al. Association of neutrophil/lymphocyte ratio and retinal vein occlusion. European journal of ophthalmology. 2015:0.

Kolar P. Risk factors for central and branch retinal vein occlusion: a meta-analysis of published clinical data. Journal of ophthalmology. 2014;2014:724780.

Martinez F, Furio E, Fabia MJ, Perez AV, Gonzalez-Albert V, Rojo-Martinez G, et al. Risk factors associated with retinal vein occlusion. International journal of clinical practice. 2014;68(7):871-81.

Shih CH, Ou SY, Shih CJ, Chen YT, Ou SM, Lee YJ. Bidirectional association between the risk of comorbidities and the diagnosis of retinal vein occlusion in an elderly population: a nationwide population-based study. International journal of cardiology. 2015;178:256-61.

Wong TY, Scott IU. Clinical practice. Retinal-vein occlusion. The New England journal of medicine. 2010;363(22):2135-44.

Sonia P Mall CAK, N Victor Chong. Current Ophthalmic Management for Retinal Vein Occlusion. European Ophthalmic Review. 2013;7(2):87–92.

The Royal College of Ophthalmology Interim guidelines for management of retinal vein occlusion. 2010.

Coscas G, Loewenstein A, Augustin A, Bandello F, Battaglia Parodi M, Lanzetta P, et al. Management of retinal vein occlusion--consensus document. Ophthalmologica Journal international d'ophtalmologie International journal of ophthalmology Zeitschrift fur Augenheilkunde. 2011;226(1):4-28.

Rehak M, Wiedemann P. Retinal vein thrombosis: pathogenesis and management. Journal of thrombosis and haemostasis : JTH. 2010;8(9):1886-94.

Fong AC, Schatz H. Central retinal vein occlusion in young adults. Survey of ophthalmology. 1993;37(6):393-417.

Bertelsen M, Linneberg A, Rosenberg T, Christoffersen N, Vorum H, Gade E, et al. Comorbidity in patients with branch retinal vein occlusion: case-control study. BMJ (Clinical research ed). 2012;345:e7885.

Published
2016-12-14
How to Cite
1.
Aghamirsalim M, Sorbi R, Naderian M, Cugati S, Shahsuvaryan M, Ghazizadeh Hashemi M. Management of Retinal Vein Occlusion, Who Is Responsible?. Acta Med Iran. 54(11):731-736.
Section
Articles