The Prevalence of Occult Hepatitis B Virus in the Hemodialysis Patients in Yazd, Iran
Occult HBV infection of hemodialysis (HD) patients is informative in terms of virus transmission. It may be of clinical importance in HD patients. The aim of this study was to investigate the prevalence of anti-HBc in the HD Patients. Number of 126 patients undergoing hemodialysis were included in this study from main hemodialysis units in Yazd. Hepatitis B surface antigens (HBsAg), hepatitis B core antibody (anti-HBc) were examined in all subjects. Finally, stored serum samples from anti-HBcAb positive, HBsAg negative patients were anonymised and tested for HBV DNA by real time quantitative PCR assay. The age range of the patients was 17-88 years. Of the 126 patients, 123 patients (97.6%) were HBC-Ab negative and 3 (2.4%) were positive. Of 3 patients with Anti-HBC positive, HBV DNA was detected in 1 patient. This study showed a low rate of isolated anti-HBc (2.4%). HBV DNA was also detected in 1 patient.
Su T, Li C, Wang J, et al. Study on risk factors of hepatitis B virus infection among patients receiving hemodialysis by multi-level statistical model analysis. Zhonghua Liu Xing Bing Xue Za Zhi 2015; 36(5):510-4.
Sowole L, Labbett W, Patel M, et al. The prevalence of occult hepatitis B virus (HBV) infection in a large multi-ethnic haemodialysis cohort. BMC Nephrol 2015; 16 (1):12.
Gasim GI, Bella A, Adam I. Immune response to hepatitis B vaccine among patients on hemodialysis. World J Hepatol 2015; 7 (2):270-5.
Fabrizi F, Dixit V, Messa P, Martin P. Transmission of hepatitis B virus in dialysis units: a systematic review of reports on outbreaks. Int J Artif Organs 2015; 38 (1):1-7.
Li X, Kang H, Wang S, et al. Knowledge, attitude, and behavior of hepatitis B virus infection among chinese dental interns. Hepat Mon 2015;15 (5):25079.
Saijo T, Joki N, Inishi Y, Muto M, Saijo M, Hase H. Occult hepatitis B virus infection in hemodialysis patients in Japan. Ther Apher Dial 2015; 19 (2):125-30.
Eleftheriadis T, Pissas G, Antoniadi G, Liakopoulos V, Stefanidis I. Factors affecting effectiveness of vaccination against hepatitis B virus in hemodialysis patients. World J Gastroenterol 2014; 20 (34):12018-25.
Kim SM, Kim HW, Lee JE, Lee EK, Shin HD, Song IH. Occult hepatitis B virus infection of hemodialysis patients: a cross-sectional study in a hepatitis B virus-endemic region. Hemodial Int 2015; 19 (1):66-71.
Bokharaei-Salim F, Keyvani H, Monavari SH, et al. Distribution of hepatitis B virus genotypes in azerbaijani patients with chronic hepatitis B infection. Hepat Mon 2014; 14 (12): 25105.
Keyvani H, Sohrabi M, Zamani F, et al. A population based study on hepatitis B virus in northern iran, amol. Hepat Mon 2014; 14 (8):20540.
Nagakawa O, Miyatomi Y, Shigeta Y, et al. Importance of isolated anti-hbc in detection of occult hepatitis B virus infection in hemodialysis patients: reply. Ther Apher Dial 2013; 17 (6):644-5.
Spaziante M, Biliotti E, Grieco S, Palazzo D, Esvan R, Taliani G. Anti-HBs seroconversion during treatment with entecavir in a patient with chronic hepatitis B virus infection on hemodialysis. J Med Virol 2014; 86 (1):139-43.
Yassin MH, Gupta V. Role of infection control in prevention of hepatitis B virus (HBV) in hemodialysis (HD) patients. Infect Disord Drug Targets 2013; 13 (3):162-8.
Rinonce HT, Yano Y, Utsumi T, et al. Hepatitis B and C virus infection among hemodialysis patients in Yogyakarta, Indonesia: Prevalence and molecular evidence for nosocomial transmission. J Med Virol 2013; 85 (8):1348-61.
Fontenele AM, Filho NS, Ferreira AS. Occult hepatitis B in patients on hemodialysis: a review. Ann Hepatol 2013; 12 (4):527-31.
Einollahi B, Alavian SM. Hepatitis B virus infection: need for more attention in hemodialysis patients. Saudi J Kidney Dis Transpl 2013; 24 (3):587-8.
Ramezani A, Banifazl M, Eslamifar A, Ahmadi F, Razeghi E, Aghakhani A. Outcome of hemodialysis patients with occult hepatitis B virus infection at a 4 year follow-up. J Gastrointestin Liver Dis 2013; 22 (1):111-2.
Mohammed AA, Enan KA, Khair OM, Hussien MO, El Hussein ARM, Elkhidir IM. Prevalence of occult hepatitis B virus (HBV) infections in haemodialysis patients in Khartoum State, Sudan from 2012 to 2014. J Med Lab Diagn 2015; 6 (4):22-26.
Elgohry I, Elbanna A, Hashad D. Occult hepatitis B virus infection in a cohort of Egyptian chronic hemodialysis patients. Clin Lab 2012; 58 (9-10):1057-61.
Ramezani A, Aghasadeghi MR, Ahmadi F, et al. Isolated anti-hbc and occult HBV infection in dialysis patients. Nephrourol Mon 2014; 7 (1): 22674.
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