The Prevalence of Occult Hepatitis B Virus in the Hemodialysis Patients in Yazd, Iran

  • Jamshid Ayatollahi Department of Infectious Diseases, Infectious Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
  • Somayeh Jahanabadi Department of Infectious Diseases, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
  • Mohammad Sharifyazdi Department of Infectious Diseases, Infectious Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
  • Roya Hemayati Department of Nephrology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
  • Mahmood Vakili Department of Community Medicine, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
  • Seyed Hossein Shahcheraghi Mail Department of Infectious Diseases, Infectious Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. AND Department of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Keywords:
Hemodialysis patients, Occult hepatitis B virus, Iran

Abstract

Occult HBV infection of hemodialysis (HD) patients is informative in terms of virus transmission. It may be of clinical importance in HD patients. The aim of this study was to investigate the prevalence of anti-HBc in the HD Patients. Number of 126 patients undergoing hemodialysis were included in this study from main hemodialysis units in Yazd. Hepatitis B surface antigens (HBsAg), hepatitis B core antibody (anti-HBc) were examined in all subjects. Finally, stored serum samples from anti-HBcAb positive, HBsAg negative patients were anonymised and tested for HBV DNA by real time quantitative PCR assay. The age range of the patients was 17-88 years. Of the 126 patients, 123 patients (97.6%) were HBC-Ab negative and 3 (2.4%) were positive. Of 3 patients with Anti-HBC positive, HBV DNA was detected in 1 patient. This study showed a low rate of isolated anti-HBc (2.4%). HBV DNA was also detected in 1 patient.

Author Biography

Seyed Hossein Shahcheraghi, Department of Infectious Diseases, Infectious Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. AND Department of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

 

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Published
2017-01-14
How to Cite
1.
Ayatollahi J, Jahanabadi S, Sharifyazdi M, Hemayati R, Vakili M, Shahcheraghi SH. The Prevalence of Occult Hepatitis B Virus in the Hemodialysis Patients in Yazd, Iran. Acta Med Iran. 54(12):784-787.
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Articles