Effect of Air Pollution in Frequency of Hospitalizations in Asthmatic Children

  • Medhi Alizadeh Department of Pediatrics, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Leila Ghasemi Hashtroodi Department of Pediatrics, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Zahra Chavoshzadeh Mail Pediatric Infections Research Center, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Nima Rezaei Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran. AND Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. AND Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
Keywords:
Asthma, Admission, Air pollution, Child

Abstract

Asthma is one of the most common diseases in childhood, which has been increased during last decade because of epidemiological pattern changes with climate and industrialization of the communities. There are some controversies on the relationship between air pollution and asthma. Tehran, as the capital of Iran, is one of the densest populations and is one of the most polluted cities in the world. This study was performed to search effects of various air pollutants using GIS-based modeling on the rate of hospitalizations due to asthma in children in Tehran. Information of patients who were admitted with a diagnosis of asthma in a referral pediatric hospital was checked and the total number of admissions in the same age range (2 to 14 years) during a 2-year period (March 2009-March 2011) were calculated. Information about air pollutants including carbon monoxide, nitrogen dioxide, ozone, and sulfur dioxide, obtained from the air quality control center. Days of the year divided into GOOD and NONGOOD days according to the guideline for reporting of the daily air quality index (AQI). Two thousand two hundred nineteen cases enrolled in the study and asthma admission to total admission ratio compared with air pollutants data in admission day (725 days), using nonlinear regression method. Analysis of the data revealed that there is a significant relationship between NONGOOD nitrogen dioxide (P=0.01), ozone (P=0.01), and sulfur dioxide (P=0.04), levels and admission due to asthma in children, but There was no significant relationship between carbon monoxide levels and asthma admission in children. A significant relationship between nitrogen dioxide, ozone and sulfur dioxide concentration in air and admission due to asthma at levels other than GOOD, reveals air pollutants levels can be significantly harmful to children before AQI reaches to hazardous levels.

References

Asthma Fact sheet N°307. (Accessed May 7, 2016, at http://www.who.int/mediacentre/factsheets/fs307/en.#/).

World Health Organization. Air quality guidelines for particulate matter, ozone, nitrogen dioxide and sulfur dioxide: global update 2005. (Accessed May 12, 2016, at http://apps.who.int/iris/bitstream/10665/69477/1/WHO_S DE_PHE_OEH_06.02_eng.pdf).

D'Amato G, Liccardi G, D'Amato M, Holgate S.Environmental risk factors and allergic bronchial asthma. Clinical and experimental allergy. Clin Exp Allergy 2005;35:1113-24.

World Health Organization. Effects of air pollution on children's health and development: a review of the evidence 2005. (Accessed May 12, 2016, at http://www.euro.who.int/ data/assets/pdf_file/0010/747 28/E86575.pdf).

Roemer W, Hoek G, Brunekreef B, Haluszka J, Kalandidi A, Pekkanen J. Daily variations in air pollution and respiratory health in a multicentre study: the PEACE project. Pollution Effects on Asthmatic Children in Europe. Eur Respiratory J 1998;12:1354-61.

Anderson HR, Butland BK, van Donkelaar A, Brauer M, Strachan DP, Clayton T, et al. Satellite-based Estimates of Ambient Air Pollution and Global Variations in Childhood Asthma Prevalence. Environ Health Perspect 2012;120:1333-9.

Gasana J, Dillikar D, Mendy A, Forno E, Ramos Vieira E, et al. Motor vehicle air pollution and asthma in children: A meta-analysis. Environ Res 2012;117:36-45.

Liapunova EV, Popova IV, Petrov BA, Beliakov VA.Impact of ambient air pollution on the prevalence of main symptoms of asthma in children. Gig Sanit 2011;2:38-41.

Tzivian L. Outdoor air pollution and asthma in children. J Asthma 2011;48:470-81.

Jerrett M, Shankardass K, Berhane K, Gauderman WJ, Künzli N, Avol E, et al. Traffic-related air pollution and asthma onset in children: a prospective cohort study with individual exposure measurement. Environ Health Perspect 2008;116:1433-8.

Published
2016-09-17
How to Cite
1.
Alizadeh M, Ghasemi Hashtroodi L, Chavoshzadeh Z, Rezaei N. Effect of Air Pollution in Frequency of Hospitalizations in Asthmatic Children. Acta Med Iran. 54(8):542-546.
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