Cutaneous Involvement in Plasma Cell Myeloma: Report of a Case
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Abstract
Plasma cellmyeloma constitutes about 10% of all hematologicmalignancies. Metastatic cutaneous lesions without underlying bony involvement are rare and associated with advanced disease, poor prognosis and high tumor burden. IgG is the most common subtype and IgD is believed to have a more aggressive course.
Guvenc B, Canataroglu A, Gumurdulu Y, Gümürdülü D, Paydaşt S. Multinple Myeloma with skin involvement. J Eur Acad Dermatol Venerol 2001;15:328-9.
Nguyen SKA, Dagnault A. Radiotherapy for multiple myeloma with skin involvement. Curr Oncol 2010;17:74- 7.
Reuena L, Kutzner H, Palmedo G, Calonje E, Requena C, Pérez G, et al. Cutaneous involvement in multiple myeloma: A clinicopathologic, immunohistochemical and cytogeneticstudy of 8 cases. Arch Dermatol 2003;139:475-89.
Bayer-Carner IB, Smoller BR. The spectrum of cutaneous disease in multiple myeloma. J Am Acad Dermatol
;48:497-507.
Blade J, Fernandez de Larrea C, Rosinol L.Extramedullary involvement in multiple myeloma. Haematologica 2012;97:1618-9.
Souza DAF, de Freitas THP, Pinto Paes RA, Muller H, Hungria VTM. Multiple myeloma with cutaneous plasmacytomas. An Bras Dermatol 2004;79:581-5.
Yoon YH, Cho WI, Seo SJ. Case of multiple meloma associated with extramedullary cutaneous plasmacytoma and pyoderma gangrenosum. Int J Dermatol 2006;45:594-7.
Usmani SZ, Heuck C, Mitchell A, Szymonifka J, Nair B, Hoering A, et al. Extramedullary disease portends poor prognosis in multiple myeloma and is over-represented in high risk disease even in the era of novel agent. Heamatologica 2012;97:1761-7.
Requena L. Specific cutaneous involvement in patients with multiple myeloma. A clinicopathological, immunohistochemical and cytogenetic study of 40 cases. Actas Dermosifiliogr 2005;96:424-40.
Jancelewicz Z, Takatsuki K, Sugai S, Pruzanski W. IgD multiple myeloma. Review of 133 cases. Arch Intern Med 1975;135:87-93.
Damaj G, Mohty M, Vey N, Dincan E, Bouabdallah R, Faucher C, et al. Features of extramedullary and extraosseous multiple myeloma: a report of 19 patients from a single center. Eur J Haematol 2004;73:402-6.
Wozney JL, Ahmed F, Bayerl MG, Ehmann WC, Talamo G. Skin involvement in immunoglobulin E multiple myeloma. J Clin Oncol 2009;27:637-8.
| Files | ||
| Issue | Vol 54, No 12 (2016) | |
| Section | Case Report(s) | |
| Keywords | ||
| Plasma cellmyeloma Skin IgD immunoglobulin | ||
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