Articles

Sexual Dysfunction in Female Hemodialysis Patients: A Cross Sectional Study in Iran

Abstract

There has been little attention to sexual dysfunction (SD) in women undergoing hemodialysis (HD), therefore few studies are found in this field. The aim of this study was to determine the incidence of SD, assess its association with biochemical factors, employment and educational status, economic situation, depression, anxiety, and medication. End stage renal disease (ESRD) married women aged 18 to 60 years presenting to Tehran University of Medical Sciences (TUMS) hospitals’ (Imam Khomeini, Sina, and Baharloo) from April to September 2017 were included in the study. Female Sexual Function Index (FSFI) questionnaire was used to evaluate SD. Patients were divided into two groups with SD (scores≤28) and without SD (scores˃28). Hospital Anxiety and Depression Scale (HADS) questionnaire was used to investigate anxiety and depression; patients with scores equal to or more than 11 were implied as depressed or anxious. Demographic data, duration of dialysis, ESRD causes and biochemical tests were also collected. Thirty patients (81.1%) out of 37 showed SD who were older, had lower educational and economic status, had higher hemoglobin levels and used erythropoietin products and Venofer® (iron sucrose injection) less; most of these patients were housewives. The incidence of SD among patients was high. Erythropoietin and Venofer use was less frequent in patients with SD compared to the other group. This suggests that these two products have a role in treatment of SD rather than the treatment of anemia.

Abouna, G.M. Organ shortage crisis: problems and possible solutions. in Transplantation proceedings. 2008. Elsevier.

Safarinejad, M., Female sexual dysfunction in a population-based study in Iran: prevalence and associated risk factors. International journal of impotence research, 2006. 18(4): p. 382.

Goldmeier, D., A. Judd, and K. Schroeder, Prevalence of sexual dysfunction in new heterosexual attenders at a central London genitourinary medicine clinic in 1998. Sexually transmitted infections, 2000. 76(3): p. 208-209.

Tehrani, F.R., et al., Factors associated with sexual dysfunction; a population based study in Iranian reproductive age women. Archives of Iranian medicine, 2014. 17(10): p. 679.

Weisbord, S.D. Sexual dysfunction and quality of life in patients on maintenance dialysis. in Seminars in dialysis. 2013. Wiley Online Library.

Rathi, M. and R. Ramachandran, Sexual and gonadal dysfunction in chronic kidney disease: Pathophysiology. Indian journal of endocrinology and metabolism, 2012. 16(2): p. 214.

Laumann, E.O., A. Paik, and R.C. Rosen, Sexual dysfunction in the United States: prevalence and predictors. Jama, 1999. 281(6): p. 537-544.

Naya, Y., et al., Significant decrease of the International Index of Erectile Function in male renal failure patients treated with hemodialysis. International journal of impotence research, 2002. 14(3): p. 172.

Navaneethan, S.D., et al., Prevalence and correlates of self-reported sexual dysfunction in CKD: a meta-analysis of observational studies. American Journal of Kidney Diseases, 2010. 56(4): p. 670-685.

Mohammadi, K., M. HEYDARI, and S. Faghihzadeh, The female sexual function index (FSFI): validation of the Iranian version. 2008.

Seethala, S., et al., Sexual function in women receiving maintenance dialysis. Hemodialysis International, 2010. 14(1): p. 55-60.

Kettaş, E., et al., Sexual dysfunction and associated risk factors in women with end‐stage renal disease. The journal of sexual medicine, 2008. 5(4): p. 872-877.

Iacovides, A., et al., Relationship of age and psychosocial factors with biological ratings in patients with end-stage renal disease undergoing dialysis. Aging clinical and experimental research, 2002. 14(5): p. 354-360.

Peng, Y.-S., et al., Sexual dysfunction in female hemodialysis patients: a multicenter study. Kidney international, 2005. 68(2): p. 760-765.

Strippoli, G.F. and S.D.i.H.W. Group, Sexual dysfunction in women with ESRD requiring hemodialysis. Clinical Journal of the American Society of Nephrology, 2012. 7(6): p. 974-981.

MahboobLessan, P. and R. Zohreh, Contributing factors in health-related quality of life assessment of ESRD patients: a single center study. Nephro-Urology Monthly, 2009(IJNU, Volume 1, Issue 2, Autumn): p. 129-136.

Santos, P.R., et al., Quality of life among women with sexual dysfunction undergoing hemodialysis: a cross-sectional observational study. Health and quality of life outcomes, 2012. 10(1): p. 103.

Altunoglu, A., et al. Relationship between inflammation and sex hormone profile in female patients receiving different types of renal replacement therapy. in Transplantation proceedings. 2014. Elsevier.

Asadifard, F., M.S. ZEIGHAMI, and B.H.T. BAHRAMI, Sexual function of women with Chronic Renal Failure Undergoing Hemodialysis and factors related to it. 2013.

Azevedo, P., et al., Sexual dysfunction in men and women on peritoneal dialysis: Differential link with metabolic factors and quality of life perception. Nefrología, 2014. 34(6): p. 703-709.

Neto, A., et al., The epidemiology of erectile dysfunction and its correlates in men with chronic renal failure on hemodialysis in Londrina, southern Brazil. International journal of impotence research, 2002. 14(S2): p. S19.

Guvel, S., Sexual Dysfunction in Women with Chronic Renal Failure&58; Assessment with the Female Sexual Function Index. Journal of Clinical and Analytical Medicine, 2013. 5(95): p. 363-365.

Resić, H., et al., Effect of erythropoietin on gonadotropic hormones and sexual function in patients on hemodialysis. Medicinski arhiv, 2004. 58(2): p. 113-115.

Peng, Y.-S., et al., The association of higher depressive symptoms and sexual dysfunction in male haemodialysis patients. Nephrology Dialysis Transplantation, 2006. 22(3): p. 857-861.

Lew‐Starowicz, M. and R. Gellert, The sexuality and quality of life of hemodialyzed patients—ASED multicenter study. The journal of sexual medicine, 2009. 6(4): p. 1062-1071.

Cukor, D., N. Ver Halen, and Y. Fruchter. Anxiety and quality of life in ESRD. in Seminars in dialysis. 2013. Wiley Online Library.

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IssueVol 57, No 4 (2019) QRcode
SectionArticles
DOI https://doi.org/10.18502/acta.v57i4.1845
Keywords
ESRD HD SD Erythropoietin Venofer Sexual dysfunction

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How to Cite
1.
Gatmiri SM, Bordbar M, Raisi F, Nourian A. Sexual Dysfunction in Female Hemodialysis Patients: A Cross Sectional Study in Iran. Acta Med Iran. 2019;57(4):244-252.