A Rare Case Report of Postmenopausal Virilization: Ovarian Steroid Cell Tumor

  • Mahbube Ebrahimpur Department of Internal Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Mohammad Reza Mohajeri-Tehrani Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Science Institute, Tehran University of Medical Sciences, Tehran, Iran.
  • Hiva Saffar Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Mahnaz Pejman Sani Mail Department of Internal Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Keywords:
Hyperandrogenism, Postmenopause, Stromal luteoma

Abstract

Ovarian steroid cell tumors are rare, life-threatening neoplasms that make about 0.1% of all primary ovarian tumors. They frequently present in premenopausal women with the manifestation of virilization. We report a 58-year-old postmenopausal woman that referred to our clinic with clinical manifestation of virilization. Laboratory findings showed markedly elevated serum testosterone level and ultrasound showed 2 follicles with 7 mm diameters in the left ovary. She treated by bilateral salpingo-oophorectomy and synchronous hysterectomy. Histological pathology confirmed a benign steroid cell tumor. The presentation of new-onset and rapid progressive hyperandrogenism is rare in postmenopausal women. In diagnosis, we must consider adrenal and ovarian malignancies. Stromal luteoma is a rare benign ovarian tumor, Which is treated with surgical treatment.

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Published
2020-06-13
How to Cite
1.
Ebrahimpur M, Mohajeri-Tehrani MR, Saffar H, Pejman Sani M. A Rare Case Report of Postmenopausal Virilization: Ovarian Steroid Cell Tumor. Acta Med Iran. 57(12):728-730.
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Case Report(s)